4.7 Review

Programmed Necrosis and Disease: We interrupt your regular programming to bring you necroinflammation

Related references

Note: Only part of the references are listed.
Review Physiology

ORIGIN AND CONSEQUENCES OF NECROINFLAMMATION

Maysa Sarhan et al.

PHYSIOLOGICAL REVIEWS (2018)

Article Multidisciplinary Sciences

RGMb protects against acute kidney injury by inhibiting tubular cell necroptosis via an MLKL- dependent mechanism

Wenjing Liu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Review Immunology

Neutrophil extracellular traps in immunity and disease

Venizelos Papayannopoulos

NATURE REVIEWS IMMUNOLOGY (2018)

Review Cell Biology

Controlled detonation: evolution of necroptosis in pathogen defense

Michelle Brault et al.

IMMUNOLOGY AND CELL BIOLOGY (2017)

Review Cell Biology

Necroptosis in development, inflammation and disease

Ricardo Weinlich et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)

Review Immunology

The in vivo evidence for regulated necrosis

Wulf Tonnus et al.

IMMUNOLOGICAL REVIEWS (2017)

Article Biochemistry & Molecular Biology

An Inflammatory Perspective on Necroptosis

Conor J. Kearney et al.

MOLECULAR CELL (2017)

Review Biochemistry & Molecular Biology

An emerging role for neutrophil extracellular traps in noninfectious disease

Selina K. Jorch et al.

NATURE MEDICINE (2017)

Article Neurosciences

Necroptosis activation in Alzheimer's disease

Antonella Caccamo et al.

NATURE NEUROSCIENCE (2017)

Article Multidisciplinary Sciences

NLRP3 mutation and cochlear autoinflammation cause syndromic and nonsyndromic hearing loss DFNA34 responsive to anakinra therapy

Hiroshi Nakanishi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Review Biochemistry & Molecular Biology

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death

Jianjin Shi et al.

TRENDS IN BIOCHEMICAL SCIENCES (2017)

Review Immunology

Programmed Cell Death and Inflammation: Winter Is Coming

Joseph P. Kolb et al.

TRENDS IN IMMUNOLOGY (2017)

Article Multidisciplinary Sciences

The emerging role of ASC in dendritic cell metabolism during Chlamydia infection

Danielle N. McKeithen et al.

PLOS ONE (2017)

Review Biochemistry & Molecular Biology

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

Brent R. Stockwell et al.

Review Biochemistry & Molecular Biology

The immune response to secondary necrotic cells

Monika Sachet et al.

APOPTOSIS (2017)

Article Biochemistry & Molecular Biology

RIPK3 Restricts Viral Pathogenesis via Cell Death-Independent Neuroinflammation

Brian P. Daniels et al.

Article Biochemistry & Molecular Biology

ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences

Yi-Nan Gong et al.

Review Immunology

Programmed cell death as a defence against infection

Ine Jorgensen et al.

NATURE REVIEWS IMMUNOLOGY (2017)

Article Cell Biology

Autophagy promotes ferroptosis by degradation of ferritin

Wen Hou et al.

AUTOPHAGY (2016)

Review Biochemistry & Molecular Biology

The clearance of dying cells: table for two

D. R. Green et al.

CELL DEATH AND DIFFERENTIATION (2016)

Article Multidisciplinary Sciences

Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells

Jennifer Martinez et al.

NATURE (2016)

Article Multidisciplinary Sciences

Pore-forming activity and structural autoinhibition of the gasdermin family

Jingjin Ding et al.

NATURE (2016)

Review Biotechnology & Applied Microbiology

Regulated necrosis: disease relevance and therapeutic opportunities

Marcus Conrad et al.

NATURE REVIEWS DRUG DISCOVERY (2016)

Review Urology & Nephrology

The role of neutrophils and NETosis in autoimmune and renal diseases

Sarthak Gupta et al.

NATURE REVIEWS NEPHROLOGY (2016)

Article Multidisciplinary Sciences

Nanoparticles size-dependently initiate self-limiting NETosis-driven inflammation

Luis E. Munoz et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Multidisciplinary Sciences

Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis

Wan Seok Yang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Multidisciplinary Sciences

RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS

Yasushi Ito et al.

SCIENCE (2016)

Review Multidisciplinary Sciences

Programmed necrosis in inflammation: Toward identification of the effector molecules

David Wallach et al.

SCIENCE (2016)

Review Urology & Nephrology

Targeting Iron Homeostasis in Acute Kidney Injury

Vyvyca J. Walker et al.

SEMINARS IN NEPHROLOGY (2016)

Review Immunology

Clearance Deficiency and Cell Death Pathways: A Model for the Pathogenesis of SLE

Aparna Mahajan et al.

FRONTIERS IN IMMUNOLOGY (2016)

Article Physiology

Proximal tubule-targeted heme oxygenase-1 in cisplatin-induced acute kidney injury

Subhashini Bolisetty et al.

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2016)

Review Immunology

Inflammasomes: mechanism of assembly, regulation and signalling

Petr Broz et al.

NATURE REVIEWS IMMUNOLOGY (2016)

Article Biochemistry & Molecular Biology

Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome

Yiqing Yan et al.

Review Immunology

Inflammasomes in host response to protozoan parasites

Dario S. Zamboni et al.

IMMUNOLOGICAL REVIEWS (2015)

Review Immunology

Pyroptotic cell death defends against intracellular pathogens

Ine Jorgensen et al.

IMMUNOLOGICAL REVIEWS (2015)

Article Biochemistry & Molecular Biology

Glutaminolysis and Transferrin Regulate Ferroptosis

Minghui Gao et al.

MOLECULAR CELL (2015)

Article Multidisciplinary Sciences

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

Nobuhiko Kayagaki et al.

NATURE (2015)

Article Multidisciplinary Sciences

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

Jianjin Shi et al.

NATURE (2015)

Review Multidisciplinary Sciences

Necroptosis and its role in inflammation

Manolis Pasparakis et al.

NATURE (2015)

Article Biochemistry & Molecular Biology

CD47 blockade triggers T cell-mediated destruction of immunogenic tumors

Xiaojuan Liu et al.

NATURE MEDICINE (2015)

Article Biochemistry & Molecular Biology

Diabetes primes neutrophils to undergo NETosis, which impairs wound healing

Siu Ling Wong et al.

NATURE MEDICINE (2015)

Article Multidisciplinary Sciences

RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8+ T cells

Nader Yatim et al.

SCIENCE (2015)

Article Multidisciplinary Sciences

Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis

Annika Warnatsch et al.

SCIENCE (2015)

Article Multidisciplinary Sciences

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

Kate E. Lawlor et al.

NATURE COMMUNICATIONS (2015)

Article Multidisciplinary Sciences

Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature

Elzbieta Kolaczkowska et al.

NATURE COMMUNICATIONS (2015)

Article Cell Biology

Activation of Necroptosis in Multiple Sclerosis

Dimitry Ofengeim et al.

CELL REPORTS (2015)

Article Multidisciplinary Sciences

Cytoprotective Effect of Ferritin H in Renal Ischemia Reperfusion Injury

Heather C. Hatcher et al.

PLOS ONE (2015)

Article Gastroenterology & Hepatology

Necroptosis Is Active in Children With Inflammatory Bowel Disease and Contributes to Heighten Intestinal Inflammation

Maria Pierdomenico et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2014)

Article Cardiac & Cardiovascular Systems

RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction

Mark Luedde et al.

CARDIOVASCULAR RESEARCH (2014)

Article Biochemistry & Molecular Biology

Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production

Michael J. White et al.

Article Biochemistry & Molecular Biology

Apoptotic Caspases Prevent the Induction of Type I Interferons by Mitochondrial DNA

Anthony Rongvaux et al.

Article Biochemistry & Molecular Biology

Regulation of Ferroptotic Cancer Cell Death by GPX4

Wan Seok Yang et al.

Article Immunology

An inherited mutation in NLRC4 causes autoinflammation in human and mice

Akiko Kitamura et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2014)

Review Biochemistry & Molecular Biology

Stress, Inflammation, and Defense of Homeostasis

Raj Chovatiya et al.

MOLECULAR CELL (2014)

Article Medicine, Research & Experimental

Increased levels of serum myeloperoxidase in patients with active rheumatoid arthritis

Wei Wang et al.

LIFE SCIENCES (2014)

Article Multidisciplinary Sciences

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

Joseph D. Mancias et al.

NATURE (2014)

Article Multidisciplinary Sciences

Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington's disease

Bindu D. Paul et al.

NATURE (2014)

Article Cell Biology

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

Jose Pedro Friedmann Angeli et al.

NATURE CELL BIOLOGY (2014)

Article Genetics & Heredity

Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation

Neil Romberg et al.

NATURE GENETICS (2014)

Review Cell Biology

Regulated necrosis: the expanding network of non-apoptotic cell death pathways

Tom Vanden Berghe et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)

Article Multidisciplinary Sciences

Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense

Xing Wang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Multidisciplinary Sciences

Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death

Dan Weng et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Immunology

Concepts of tissue injury and cell death in inflammation: a historical perspective

David Wallach et al.

NATURE REVIEWS IMMUNOLOGY (2014)

Review Immunology

Apoptotic cell clearance: basic biology and therapeutic potential

Ivan K. H. Poon et al.

NATURE REVIEWS IMMUNOLOGY (2014)

Article Endocrinology & Metabolism

Upregulated NLRP3 Inflammasome Activation in Patients With Type 2 Diabetes

Hye-Mi Lee et al.

DIABETES (2013)

Article Gastroenterology & Hepatology

Absence of Receptor Interacting Protein Kinase 3 Prevents Ethanol-Induced Liver Injury

Sanjoy Roychowdhury et al.

HEPATOLOGY (2013)

Review Immunology

Immune Sensing of DNA

Soren R. Paludan et al.

IMMUNITY (2013)

Article Biochemistry & Molecular Biology

Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL

William J. Kaiser et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Immunology

Macrophage Clearance of Neutrophil Extracellular Traps Is a Silent Process

Consol Farrera et al.

JOURNAL OF IMMUNOLOGY (2013)

Article Multidisciplinary Sciences

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice

Michael T. Heneka et al.

NATURE (2013)

Article Multidisciplinary Sciences

Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury

Andreas Linkermann et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication

Martin R. Jakobsen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases

Roshan J. Thapa et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Caspase-11 Protects Against Bacteria That Escape the Vacuole

Youssef Aachoui et al.

SCIENCE (2013)

Article Cell Biology

Clearing the Dead: Apoptotic Cell Sensing, Recognition, Engulfment, and Digestion

Amelia Hochreiter-Hufford et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)

Review Cell Biology

Inflammasomes and Their Roles in Health and Disease

Mohamed Lamkanfi et al.

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 28 (2012)

Article Biochemistry & Molecular Biology

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon et al.

Article Biochemistry & Molecular Biology

Gpx4 ablation in adult mice results in a lethal phenotype accompanied by neuronal loss in brain

Si-Eun Yoo et al.

FREE RADICAL BIOLOGY AND MEDICINE (2012)

Review Immunology

PAMPs and DAMPs: signal 0s that spur autophagy and immunity

Daolin Tang et al.

IMMUNOLOGICAL REVIEWS (2012)

Article Multidisciplinary Sciences

Receptor interacting protein kinase mediates necrotic cone but not rod cell death in a mouse model of inherited degeneration

Yusuke Murakami et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Oncology

Immunogenic cell death and DAMPs in cancer therapy

Dmitri V. Krysko et al.

NATURE REVIEWS CANCER (2012)

Review Biochemistry & Molecular Biology

Metabolic Connections during Apoptotic Cell Engulfment

Claudia Z. Han et al.

Review Immunology

Armed response: how dying cells influence T-cell functions

Thomas A. Ferguson et al.

IMMUNOLOGICAL REVIEWS (2011)

Article Multidisciplinary Sciences

RIP3 mediates the embryonic lethality of caspase-8-deficient mice

William J. Kaiser et al.

NATURE (2011)

Article Multidisciplinary Sciences

Catalytic activity of the caspase-8-FLIPL complex inhibits RIPK3-dependent necrosis

Andrew Oberst et al.

NATURE (2011)

Article Multidisciplinary Sciences

Hepcidin Is Involved in Iron Regulation in the Ischemic Brain

Hui Ding et al.

PLOS ONE (2011)

Article Multidisciplinary Sciences

Inflammasome is a central player in the induction of obesity and insulin resistance

Rinke Stienstra et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

Jennifer Martinez et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Review Biophysics

The Distribution and Function of Phosphatidylserine in Cellular Membranes

Peter A. Leventis et al.

ANNUAL REVIEW OF BIOPHYSICS, VOL 39 (2010)

Review Biochemistry & Molecular Biology

Autoimmunity and the Clearance of Dead Cells

Shigekazu Nagata et al.

Review Biochemistry & Molecular Biology

Secondary necrosis: The natural outcome of the complete apoptotic program

Manuel T. Silva

FEBS LETTERS (2010)

Article Cell Biology

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

Venizelos Papayannopoulos et al.

JOURNAL OF CELL BIOLOGY (2010)

Article Immunology

Find-me and eat-me signals in apoptotic cell clearance: progress and conundrums

Kodi S. Ravichandran

JOURNAL OF EXPERIMENTAL MEDICINE (2010)

Review Cell Biology

Mitochondria and cell death: outer membrane permeabilization and beyond

Stephen W. G. Tait et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)

Article Multidisciplinary Sciences

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

Abdul Hakkim et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Immunology

Approaching the Asymptote: 20 Years Later

Ruslan Medzhitov

IMMUNITY (2009)

Article Multidisciplinary Sciences

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

Michael R. Elliott et al.

NATURE (2009)

Article Genetics & Heredity

Common variants in the NLRP3 region contribute to Crohn's disease susceptibility

Alexandra-Chloe Villani et al.

NATURE GENETICS (2009)

Review Immunology

Death receptor signal transducers: nodes of coordination in immune signaling networks

Nicholas S. Wilson et al.

NATURE IMMUNOLOGY (2009)

Article Biochemistry & Molecular Biology

PPAR-δ senses and orchestrates clearance of apoptotic cells to promote tolerance

Lata Mukundan et al.

NATURE MEDICINE (2009)

Article Biochemistry & Molecular Biology

Netting neutrophils in autoimmune small-vessel vasculitis

Kai Kessenbrock et al.

NATURE MEDICINE (2009)

Review Microbiology

Pyroptosis: host cell death and inflammation

Tessa Bergsbaken et al.

NATURE REVIEWS MICROBIOLOGY (2009)

Article Endocrinology & Metabolism

Necrostatin-1 reduces histopathology and improves functional outcome after controlled cortical impact in mice

Zerong You et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2008)

Article Immunology

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

Annett Halle et al.

NATURE IMMUNOLOGY (2008)

Article Multidisciplinary Sciences

Antigen-mediated T cell expansion regulated by parallel pathways of death

Irene L. Ch'en et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Medicine, General & Internal

Interleukin-1-receptor antagonist in type 2 diabetes mellitus

Claus M. Larsen et al.

NEW ENGLAND JOURNAL OF MEDICINE (2007)

Article Biochemistry & Molecular Biology

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

A Degterev et al.

NATURE CHEMICAL BIOLOGY (2005)

Article Multidisciplinary Sciences

Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice

R Hanayama et al.

SCIENCE (2004)

Article Cardiac & Cardiovascular Systems

Reduced atherosclerosis in interleukin-18 deficient apolipoprotein E-knockout mice

R Elhage et al.

CARDIOVASCULAR RESEARCH (2003)

Article Biochemistry & Molecular Biology

The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults

LJ Yant et al.

FREE RADICAL BIOLOGY AND MEDICINE (2003)

Article Multidisciplinary Sciences

The danger model: A renewed sense of self

P Matzinger

SCIENCE (2002)