Journal
CELL
Volume 176, Issue 1-2, Pages 4-6Publisher
CELL PRESS
DOI: 10.1016/j.cell.2018.12.020
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Funding
- NIH [5R35GM126942]
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Regulation of protein-DNA binding specificity occurs through myriad mechanisms. Boudet et al. discover yet a new form of specificity through allosteric regulation, an ATP-induced structural switch that mediates specific DNA recognition in an archaeoeukaryotic primase.
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