Related references
Note: Only part of the references are listed.Small Molecule Allosteric Modulators of G-Protein-Coupled Receptors: Drug-Target Interactions
Shaoyong Lu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
GPCRdb in 2018: adding GPCR structure models and ligands
Gaspar Pandy-Szekeres et al.
NUCLEIC ACIDS RESEARCH (2018)
Unexplored therapeutic opportunities in the human genome
Tudor I. Oprea et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
Chemical Diversity in the G Protein-Coupled Receptor Superfamily
Marton Vass et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2018)
A comprehensive map of molecular drug targets
Rita Santos et al.
NATURE REVIEWS DRUG DISCOVERY (2017)
Pharos: Collating protein information to shed light on the druggable genome
Dac-Trung Nguyen et al.
NUCLEIC ACIDS RESEARCH (2017)
The Monarch Initiative: an integrative data and analytic platform connecting phenotypes to genotypes across species
Christopher J. Mungall et al.
NUCLEIC ACIDS RESEARCH (2017)
Open Targets: a platform for therapeutic target identification and validation
Gautier Koscielny et al.
NUCLEIC ACIDS RESEARCH (2017)
DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants
Janet Pinero et al.
NUCLEIC ACIDS RESEARCH (2017)
Targeting proteasomes in infectious organisms to combat disease
Betsaida Bibo-Verdugo et al.
FEBS JOURNAL (2017)
In silico prediction of novel therapeutic targets using gene-disease association data
Enrico Ferrero et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2017)
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
Katrina M. de lange et al.
NATURE GENETICS (2017)
Trends in GPCR drug discovery: new agents, targets and indications
Alexander S. Hauser et al.
NATURE REVIEWS DRUG DISCOVERY (2017)
Neuropeptide S (NPS) variants modify the signaling and risk effects of NPS Receptor 1 (NPSR1) variants in asthma
Nathalle Acevedo et al.
PLOS ONE (2017)
The druggable genome and support for target identification and validation in drug development
Chris Finan et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
Literature evidence in open targets - a target validation platform
Senay Kafkas et al.
JOURNAL OF BIOMEDICAL SEMANTICS (2017)
The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands
Christopher Southan et al.
NUCLEIC ACIDS RESEARCH (2016)
Protein profiles of CCL5, HPGDS, and NPSR1 in plasma reveal association with childhood asthma
C. Hamsten et al.
ALLERGY (2016)
Vasopressin receptor antagonists: Characteristics and clinical role
Helbert Rondon-Berrios et al.
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2016)
Homology modeling, docking, and molecular dynamics simulation of the receptor GALR2 and its interactions with galanin and a positive allosteric modulator
Wen-Qi Hui et al.
JOURNAL OF MOLECULAR MODELING (2016)
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease
Robert A. Scott et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Computational approaches in target identification and drug discovery
Theodora Katsila et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2016)
Peptide therapeutics: current status and future directions
Keld Fosgerau et al.
DRUG DISCOVERY TODAY (2015)
Galanin pathogenic mutations in temporal lobe epilepsy
Michel Guipponi et al.
HUMAN MOLECULAR GENETICS (2015)
DISEASES: Text mining and data integration of disease-gene associations
Sune Pletscher-Frankild et al.
METHODS (2015)
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
Jimmy Z. Liu et al.
NATURE GENETICS (2015)
Orchestrating high-throughput genomic analysis with Bioconductor
Wolfgang Huber et al.
NATURE METHODS (2015)
The therapeutic potential of orphan GPCRs, GPR35 and GPR55
Derek M. Shore et al.
FRONTIERS IN PHARMACOLOGY (2015)
G protein-coupled receptor 35: an emerging target in inflammatory and cardiovascular disease
Nina Divorty et al.
FRONTIERS IN PHARMACOLOGY (2015)
Cutting Edge: GPR35/CXCR8 Is the Receptor of the Mucosal Chemokine CXCL17
Jose L. Maravillas-Montero et al.
JOURNAL OF IMMUNOLOGY (2015)
The Druggable Genome: Evaluation of Drug Targets in Clinical Trials Suggests Major Shifts in Molecular Class and Indication
Mathias Rask-Andersen et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 54 (2014)
CXCR4: A virus's best friend?
Kathleen L. Arnolds et al.
INFECTION GENETICS AND EVOLUTION (2014)
Neuropeptides as Targets for the Development of Anticonvulsant Drugs
Elke Clynen et al.
MOLECULAR NEUROBIOLOGY (2014)
Enhanced expression of neuropeptide S (NPS) receptor in eosinophils from severe asthmatics and subjects with total IgE above 100 IU/ml
Pinja Ilmarinen et al.
PEPTIDES (2014)
Incidence and Phenotype of Inflammatory Bowel Disease Based on Results From the Asia-Pacific Crohn's and Colitis Epidemiology Study
Siew C. Ng et al.
GASTROENTEROLOGY (2013)
Activation of T cell death-associated gene 8 regulates the cytokine production of T cells and macrophages in vitro
Yoshiko Onozawa et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2012)
Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review
Natalie A. Molodecky et al.
GASTROENTEROLOGY (2012)
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
Carl A. Anderson et al.
NATURE GENETICS (2011)
The role of neuropeptide S and neuropeptide S receptor 1 in regulation of respiratory function in mice
Hongyan Zhu et al.
PEPTIDES (2011)
Modeling sample variables with an Experimental Factor Ontology
James Malone et al.
BIOINFORMATICS (2010)
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
Andre Franke et al.
NATURE GENETICS (2010)
The G protein-coupled receptor T-cell death-associated gene 8 (TDAG8) facilitates tumor development by serving as an extracellular pH sensor
Yuichiro Ihara et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Involvement of Proton-Sensing TDAG8 in Extracellular Acidification-Induced Inhibition of Proinflammatory Cytokine Production in Peritoneal Macrophages
Chihiro Mogi et al.
JOURNAL OF IMMUNOLOGY (2009)
Drugs targeting protein-protein interactions
Patrick Chene
CHEMMEDCHEM (2006)
G-protein-coupled receptor polymorphisms are associated with asthma in a large German population
MSD Kormann et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2005)
Haplotypes of G protein-coupled receptor 154 are associated with childhood allergy and asthma
E Melén et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2005)
Identification of T cell death-associated gene 8 ( TDAG8) as a novel acid sensing G-protein-coupled receptor
S Ishii et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
TDAG8 is a proton-sensing and psychosine-sensitive G-protein-coupled receptor
JQ Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Galanin:: An endogenous anticonvulsant?
A Mazarati et al.
NEUROSCIENTIST (2001)
Share Paper
