Journal
BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
Volume 66, Issue 2, Pages 153-162Publisher
WILEY
DOI: 10.1002/bab.1720
Keywords
biomass; Cupriavidus necator; laccase; lignin; microbial diversity; polyhydroxyalkanoates; Pseudomonas
Funding
- National Research Foundation of Korea [NRF-2017R1A2B4002371]
- Brain Korea 21 plus project grant
- National Research Foundation of Korea [21A20130000013] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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Renewable energy resources are considered to be promising for the development of a sustainable circular economy. Among various alternatives, the microbial route for various biofuels production is quite lucrative. Use of cellulose and lignocellulose for methane, H-2, organic acids, ethanol, and cellulase has been explored a lot in the past few decades. The major leftover or a coproduct of these processes belongs to lignin-an aromatic cross-link polymer and one of the most abundant complex compounds on earth. A successful bioconversion route of lignin into high-value products is highly desirable for biorefinery perspective. It requires a complex set of enzymes/catalysts to decompose lignin through depolymerization and oxygen removal leading to its monomers that can be metabolized by engineered organisms to synthesize muconic acids, polyhydroxyalkanoates (PHAs), methane, and other high-value products. This article will focus on the opportunities and challenges in the bioconversion of lignin and its derivatives into PHAs.
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