Journal
BIOMETRICAL JOURNAL
Volume 62, Issue 3, Pages 742-750Publisher
WILEY
DOI: 10.1002/bimj.201800255
Keywords
Cox regression model; hazard ratio; probabilistic index; relative risk; survival analysis
Funding
- Fonds Wetenschappelijk Onderzoek [G020214N, K154117N, V403114N]
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We argue that the term relative risk should not be used as a synonym for hazard ratio and encourage to use the probabilistic index as an alternative effect measure for Cox regression. The probabilistic index is the probability that the event time of an exposed or treated subject exceeds the event time of an unexposed or untreated subject conditional on the other covariates. It arises as a well known and simple transformation of the hazard ratio and nicely reveals the interpretational limitations. We demonstrate how the probabilistic index can be obtained using the R-package Publish.
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