4.7 Article

wgd-simple command line tools for the analysis of ancient whole-genome duplications

Journal

BIOINFORMATICS
Volume 35, Issue 12, Pages 2153-2155

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/bty915

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Funding

  1. European Union Seventh Framework Programme (FP7/2007-2013) under European Research Council [322739-DOUBLEUP]
  2. Research Foundation-Flanders (FWO)

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.Summary Ancient whole-genome duplications (WGDs) have been uncovered in almost all major lineages of life on Earth and the search for traces or remnants of such events has become standard practice in most genome analyses. This is especially true for plants, where ancient WGDs are abundant. Common approaches to find evidence for ancient WGDs include the construction of K-S distributions and the analysis of intragenomic colinearity. Despite the increased interest in WGDs and the acknowledgment of their evolutionary importance, user-friendly and comprehensive tools for their analysis are lacking. Here, we present an easy to use command-line tool for K-S distribution construction named wgd. The wgd suite provides commonly used K-S and colinearity analysis workflows together with tools for modeling and visualization, rendering these analyses accessible to genomics researchers in a convenient manner. Availability and implementation wgd is free and open source software implemented in Python and is available at https://github.com/arzwa/wgd. Supplementary information Supplementary data are available at Bioinformatics online.

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