Journal
BIOINFORMATICS
Volume 35, Issue 17, Pages 3171-3173Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btz022
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Funding
- London Interdisciplinary Biosciences Consortium (LIDo) BBSRC Doctoral Training Partnership [BB/M009513/1]
- Wellcome Trust [109854/Z/15/Z]
- Medical Research Council [MC_PC_15031]
- BBSRC [1622063] Funding Source: UKRI
- MRC [MC_PC_15031] Funding Source: UKRI
- Wellcome Trust [109854/Z/15/Z] Funding Source: Wellcome Trust
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The Summary: Hydrogen deuterium exchange-mass spectrometry (HDX-MS) has emerged as a powerful technique for interrogating the conformational dynamics of proteins and their complexes. Currently, analysis of HDX-MS data remains a laborious procedure, mainly due to the lack of streamlined software to process the large datasets. We present Deuteros which is a standalone software designed to be coupled with Waters DynamX HDX data analysis software, allowing the rapid analysis and visualization of data from differential HDX-MS.
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