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EMBO JOURNAL (2009)
Update of Cylindromatosis Gene (CYLD) Mutations in Brooke-Spiegler Syndrome: Novel Insights Into the Role of Deubiquitination in Cell Signaling
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HUMAN MUTATION (2009)
UAF1 Is a Subunit of Multiple Deubiquitinating Enzyme Complexes
Martin A. Cohn et al.
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OTU Domain-containing Ubiquitin Aldehyde-binding Protein 1 (OTUB1) Deubiquitinates Estrogen Receptor (ER) α and Affects ERα Transcriptional Activity
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The Deubiquitinating Enzyme BAP1 Regulates Cell Growth via Interaction with HCF-1
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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The Epstein-Barr Virus (EBV) Deubiquitinating Enzyme BPLF1 Reduces EBV Ribonucleotide Reductase Activity
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JOURNAL OF VIROLOGY (2009)
Adenovirus E1B 55-Kilodalton Protein: Multiple Roles in Viral Infection and Cell Transformation
Andrew N. Blackford et al.
JOURNAL OF VIROLOGY (2009)
Association of C-Terminal Ubiquitin Hydrolase BRCA1-Associated Protein 1 with Cell Cycle Regulator Host Cell Factor 1
Shahram Misaghi et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Dissection of USP catalytic domains reveals five common insertion points
Yu Ye et al.
MOLECULAR BIOSYSTEMS (2009)
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MOLECULAR CANCER THERAPEUTICS (2009)
Gcn5 and SAGA Regulate Shelterin Protein Turnover and Telomere Maintenance
Boyko S. Atanassov et al.
MOLECULAR CELL (2009)
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins
Camilla Raiborg et al.
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Involvement of linear polyubiquitylation of NEMO in NF-κB activation
Fuminori Tokunaga et al.
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Breaking the chains: structure and function of the deubiquitinases
David Komander et al.
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CRL4s: the CUL4-RING E3 ubiquitin ligases
Sarah Jackson et al.
TRENDS IN BIOCHEMICAL SCIENCES (2009)
Genome-Wide Analysis of Factors Affecting Transcription Elongation and DNA Repair: A New Role for PAF and Ccr4-Not in Transcription-Coupled Repair
Helene Gaillard et al.
PLOS GENETICS (2009)
Targeting PI3K signalling in cancer: opportunities, challenges and limitations
Jeffrey A. Engelman
NATURE REVIEWS CANCER (2009)
Rest and the restless: in stem cells and beyond
Vidya Gopalakrishnan
FUTURE NEUROLOGY (2009)
Protein partners of deubiquitinating enzymes
Karen H. Ventii et al.
BIOCHEMICAL JOURNAL (2008)
Ubiquitin and ubiquitin-like specific proteases targeted by infectious pathogens: Emerging patterns and molecular principles
Mariola J. Edelmann et al.
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BRCA1-associated protein-1 is a tumor suppressor that requires deubiquitinating activity and nuclear localization
Karen H. Ventii et al.
CANCER RESEARCH (2008)
USP22, an hSAGA subunit and potential cancer stem cell marker, reverses the polycomb-catalyzed ubiquitylation of histone H2A
Xiao-Yong Zhang et al.
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Tumor suppressor CYLD: negative regulation of NF-kappa B signaling and more
G. Courtois
CELLULAR AND MOLECULAR LIFE SCIENCES (2008)
Deubiquitylation of histone H2A activates transcriptional initiation via trans-histone cross-talk with H3K4 di- and trimethylation
Takeya Nakagawa et al.
GENES & DEVELOPMENT (2008)
The tumor suppressor CYLD regulates microtubule dynamics and plays a role in cell migration
Jinmin Gao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis
Akiko Mukai et al.
JOURNAL OF CELL SCIENCE (2008)
The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression
Xiao-Yong Zhang et al.
MOLECULAR CELL (2008)
A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing
Yue Zhao et al.
MOLECULAR CELL (2008)
The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module
David Komander et al.
MOLECULAR CELL (2008)
Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains
Yusuke Sato et al.
NATURE (2008)
The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network
Min Sup Song et al.
NATURE (2008)
SCFβ-TRCP controls oncogenic transformation and neural differentiation through REST degradation
Thomas F. Westbrook et al.
NATURE (2008)
T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-κB inhibitor A20
Beatrice Coornaert et al.
NATURE IMMUNOLOGY (2008)
A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication
Kiira Ratia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Capturing protein tails by CAP-Gly domains
Michel O. Steinmetz et al.
TRENDS IN BIOCHEMICAL SCIENCES (2008)
Zinc-finger UBPs: regulators of deubiquitylation
Jacques Bonnet et al.
TRENDS IN BIOCHEMICAL SCIENCES (2008)
A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway
Martin A. Cohn et al.
MOLECULAR CELL (2007)
A herpesvirus ubiquitin-specific protease is critical for efficient T cell lymphoma formation
Keith Jarosinski et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Profiling of UV-induced ATM/ATR signaling pathways
Matthew P. Stokes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
DUBA: A deubiquitinase that regulates type I interferon production
Nobuhiko Kayagaki et al.
SCIENCE (2007)
Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells
Julie K. Stock et al.
NATURE CELL BIOLOGY (2007)
Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses
Natalia Frias-Staheli et al.
CELL HOST & MICROBE (2007)
Regulation of cell cycle progression and gene expression by H2A deubiquitination
Heui-Yun Joo et al.
NATURE (2007)
High incidence of ubiquitin-like domains in human ubiquitin-specific proteases
Xiao Zhu et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2007)
ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration
Jin-A Lee et al.
CURRENT BIOLOGY (2007)
Salmonella effector AvrA regulation of colonic epithelial cell inflammation by deubiquitination
Zhongde Ye et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
Solution structure of the Ubp-M BUZ domain, a highly specific protein module that recognizes the C-terminal tail of free ubiquitin
Ming-Tao Pai et al.
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The ubiquitin-specific protease USP28 is required for MYC stability
Nikita Popov et al.
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Chromatin crosstalk in development and disease: lessons from REST
Lezanne Ooi et al.
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Parallels between cytokinesis and retroviral budding: A role for the ESCRT machinery
Jez G. Carlton et al.
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Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages
Hyoung Tae Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities
Frank Stegmeier et al.
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Structure of a herpesvirus-encoded cysteine protease reveals a unique class of deubiquitinating enzymes
Christian Schlieker et al.
MOLECULAR CELL (2007)
The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2
Lauren F. Stevenson et al.
EMBO JOURNAL (2007)
Ataxin-3 represses transcription via chromatin binding, interaction with histone deacetylase 3, and histone deacetylation
Bernd O. Evert et al.
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FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP
Armando van der Horst et al.
NATURE CELL BIOLOGY (2006)
A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response
Dong Zhang et al.
CELL (2006)
Clathrin anchors deubiquitinating enzymes, AMSH and AMSH-like protein, on early endosomes
Michihiko Nakamura et al.
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Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II
Rushad Pavri et al.
CELL (2006)
Cylindroma as tumor of hair follicle origin
Ramin Massoumi et al.
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Molecular recognition of p53 and MDM2 by USP7/HAUSP
Y Sheng et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)
A genomic and functional inventory of deubiquitinating enzymes
SMB Nijman et al.
CELL (2005)
Yersinia virulence factor YopJ acts as a deubiquitinase to inhibit NF-κB activation
HL Zhou et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14
M Hu et al.
EMBO JOURNAL (2005)
Helix-loop-helix proteins and lymphocyte development
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The many faces of REST oversee epigenetic programming of neuronal genes
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CURRENT OPINION IN NEUROBIOLOGY (2005)
At least two regions of the oncoprotein Tre2 are involved in its lack of GAP activity
C Bizimungu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Topology of transmembrane segments 1-4 in the human chloride/bicarbonate anion exchanger 1 (AE1) by scanning N-glycosylation mutagenesis
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BIOCHEMICAL JOURNAL (2005)
ID family of helix-loop-helix proteins in cancer
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Weighing in on ubiquitin: the expanding role of mass-spectrometry-based proteomics
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NATURE CELL BIOLOGY (2005)
Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer
GV Glinsky et al.
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REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis
N Ballas et al.
CELL (2005)
A dynamic role of HAUSP in the p53-Mdm2 pathway
MY Li et al.
MOLECULAR CELL (2004)
Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity
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BIOCHEMICAL JOURNAL (2004)
The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer
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CANCER CELL (2004)
Ras regulates assembly of mitogenic signalling complexes through the effector protein IMP
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NATURE (2004)
The CAP-Gly domain with the proline-rich of CYLD associates sequence in NEMO/IKKγ
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STRUCTURE (2004)
AMSH is an endosome-associated ubiquitin isopeptidase
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JOURNAL OF CELL BIOLOGY (2004)
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling
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NATURE (2004)
The TBC (Tre-2/Bub2/Cdc16) domain protein TRE17 regulates plasma membrane-endosomal trafficking through activation of Arf6
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MOLECULAR AND CELLULAR BIOLOGY (2004)
The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses
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NATURE IMMUNOLOGY (2004)
The polyglutamine neurodegenerative protein ataxin-3 binds polyubiquitylated proteins and has ubiquitin protease activity
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HUMAN MOLECULAR GENETICS (2003)
The tumour suppressor CYLD negatively regulates NF-κB signalling by deubiquitination
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NATURE (2003)
CYLD is a deubiquitinating enzyme that negatively regulates NF-κB activation by TNFR family members
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NATURE (2003)
Ubiquitin-mediated sequestration of normal cellular proteins into polyglutamine aggregates
KM Donaldson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
A novel type of deubiquitinating enzyme*
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Otubains: a new family of cysteine proteases in the ubiquitin pathway
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EMBO REPORTS (2003)
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GENE (2003)
Elucidation of ataxin-3 and ataxin-7 function by integrative bioinformatics
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HUMAN MOLECULAR GENETICS (2003)
Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8
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GENES & DEVELOPMENT (2003)
Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1
GA Cope et al.
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Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome
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SCIENCE (2002)
Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme
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A cryptic protease couples deubiquitination and degradation by the proteasome
TT Yao et al.
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Deubiquitinating function of adenovirus proteinase
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JOURNAL OF VIROLOGY (2002)
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization
MY Li et al.
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Role of id family proteins in growth control
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JOURNAL OF CELLULAR PHYSIOLOGY (2002)
Chemical approaches for functionally probing the proteome
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CELL DEATH AND DIFFERENTIATION (2001)
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