Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 58, Issue 16, Pages 5190-5200Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201809607
Keywords
array-based sensing; biomedicine; cancer cell detection; diagnosis; protein detection
Categories
Funding
- NIH [GM077173, CA207932, AI AI134770]
- Chemistry Biology Interface program at University of Massachusetts Amherst [GM008515]
- Royal Society
- University of Glasgow
- Killam Foundation
Ask authors/readers for more resources
Array-based sensor chemical nose/tongue platforms are inspired by the mammalian olfactory system. Multiple sensor elements in these devices selectively interact with target analytes; producing a distinct pattern of response and enabling analytes identification. This approach offers unique opportunities relative to traditional highly specific sensor elements such as antibodies. Array-based sensors excel at distinguishing small changes in complex mixtures, and this capability is being leveraged for chemical biology studies and clinical pathology, enabled by a diverse toolkit of new molecular, bioconjugate and nanomaterial technologies. Innovation in the design and analysis of arrays provides a robust set of tools or advancing biomedical goals, including precision medicine.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available