Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 58, Issue 12, Pages 4046-4050Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201814373
Keywords
functionalized organometallics; halogen samarium exchange; kinetics; lanthanides; samarium
Categories
Funding
- LMU Munich
- Humboldt foundation
Ask authors/readers for more resources
Fast I/Sm and Br/Sm exchanges take place when various aromatic or heterocyclic iodides and bromides are treated with nBu(2)SmCl.4 LiCl and nBu(3)Sm.5 LiCl, respectively. The resulting organosamarium reagents were efficiently quenched with aldehydes, ketones, and imine& Also, they undergo acylations when treated with N,N-dimethylamides leading to ketones. The rate of the Br/Sm exchange for a typical aryl bromide was determined and found to be 8.5 x 10(5) faster than the Br/Mg exchange, indicating that the rate of a metal exchange is related to the ionic character of the carbon-metal bond and to the metal electronegativity.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available