Journal
ADVANCED SYNTHESIS & CATALYSIS
Volume 361, Issue 11, Pages 2668-2672Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201801312
Keywords
biocatalysis; oxidase; two liquid phase system; oxidation reactions
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Funding
- Netherlands Organisation for Scientific Research [724.014.003]
- Delft University of Technology
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The selective oxidation of trans-2-hexen-1-ol to the corresponding aldehyde using a recombinant aryl alcohol oxidase from Pleurotus eryngii (PeAAOx) is reported. Especially using the two liquid phase system to overcome solubility and product inhibition issues enabled to achieve more than 2.200.000 catalytic turnovers for the production enzyme as well as molar product concentrations, pointing towards an economic feasible reaction.
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