4.6 Review

Gold nanoparticles - the theranostic challenge for PPPM: nanocardiology application

Journal

EPMA JOURNAL
Volume 4, Issue 1, Pages -

Publisher

SPRINGER INT PUBL AG
DOI: 10.1186/1878-5085-4-18

Keywords

Predictive; Preventive and Personalised Medicine; Nanomedicine; Gold Nanoparticles; Drug Delivery; Sonoporation; Theranostics

Funding

  1. State Agency on Science, Innovations and Informatisation of Ukraine [D./490-2011]

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The article overviews the potential biomedical applications of nanoscale gold particles for predictive, preventive and personalised nanomedicine in cardiology. The review demonstrates the wide opportunities for gold nanoparticles due to their unique biological properties. The use of gold nanoparticles in cardiology is promising to develop fundamentally new methods of diagnosis and treatment. The nanotheranostics in cardiovascular diseases allows the non-invasive imaging associated with simultaneous therapeutic intervention and predicting treatment outcomes. Imaging may reflect the effectiveness of treatment and has become a fundamental optimisation setting for therapeutic protocol. Combining the application of biomolecular and cellular therapies with nanotechnologies foresees the development of complex integrated nanodevices. Nanocardiology may challenge existing healthcare system and economic benefits as cardiovascular diseases are the leading cause of morbidity and mortality at present.

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