Related references
Note: Only part of the references are listed.ALKBH5-dependent m6A demethylation controls splicing and stability of long 3 '-UTR mRNAs in male germ cells
Chong Tang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Signaling Pathways Driving Aberrant Splicing in Cancer Cells
Vania Goncalves et al.
GENES (2018)
Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability
Kenichi Iwai et al.
EMBO MOLECULAR MEDICINE (2018)
Metabolic Alterations in Cancer Cells and the Emerging Role of Oncometabolites as Drivers of Neoplastic Change
Zhengqiu Zhou et al.
ANTIOXIDANTS (2018)
RBM4 Regulates Neuronal Differentiation of Mesenchymal Stem Cells by Modulating Alternative Splicing of Pyruvate Kinase M
Chun-Hao Su et al.
MOLECULAR AND CELLULAR BIOLOGY (2017)
JMJD6 and U2AF65 co-regulate alternative splicing in both JMJD6 enzymatic activity dependent and independent manner
Jia Yi et al.
NUCLEIC ACIDS RESEARCH (2017)
The bromodomain protein BRD4 regulates splicing during heat shock
Michelle Hussong et al.
NUCLEIC ACIDS RESEARCH (2017)
Cell survival: Interplay between hypoxia and pre-mRNA splicing
Arvydas Kanopka
EXPERIMENTAL CELL RESEARCH (2017)
The role of RNA alternative splicing in regulating cancer metabolism
Itamar Kozlovski et al.
HUMAN GENETICS (2017)
Histone arginine demethylase JMJD6 is linked to stress granule assembly through demethylation of the stress granule-nucleating protein G3BP1
Wei-Chih Tsai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
NEK2 Promotes Aerobic Glycolysis in Multiple Myeloma Through Regulating Splicing of Pyruvate Kinase
Zhimin Gu et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2017)
JMJD6 promotes melanoma carcinogenesis through regulation of the alternative splicing of PAK1, a key MAPK signaling component
Xujun Liu et al.
MOLECULAR CANCER (2017)
Quercetin Targets hnRNPA1 to Overcome Enzalutamide Resistance in Prostate Cancer Cells
Ramakumar Tummala et al.
MOLECULAR CANCER THERAPEUTICS (2017)
Multilayered Control of Alternative Splicing Regulatory Networks by Transcription Factors
Hong Han et al.
MOLECULAR CELL (2017)
Splicing and transcription touch base: co-transcriptional spliceosome assembly and function
Lydia Herzel et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
N6-methyladenosine demethylase FTO targets pre-mRNAs and regulates alternative splicing and 3'-end processing
Marek Bartosovic et al.
NUCLEIC ACIDS RESEARCH (2017)
H3K4 demethylase KDM5B regulates global dynamics of transcription elongation and alternative splicing in embryonic stem cells
Runsheng He et al.
NUCLEIC ACIDS RESEARCH (2017)
Intragenic DNA methylation and BORIS-mediated cancer-specific splicing contribute to the Warburg effect
Smriti Singh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Phosphorylation of Ser6 in hnRNPA1 by S6K2 regulates glucose metabolism and cell growth in colorectal cancer
Yan Sun et al.
ONCOLOGY LETTERS (2017)
The Functional Impact of Alternative Splicing in Cancer
Hector Climente-Gonzalez et al.
CELL REPORTS (2017)
MeCP2 regulates Tet1-catalyzed demethylation, CTCF binding, and learning-dependent alternative splicing of the BDNF gene in Turtle
Zhaoqing Zheng et al.
ELIFE (2017)
Jmjd6, a JmjC Dioxygenase with Many Interaction Partners and Pleiotropic Functions
Janice Kwok et al.
FRONTIERS IN GENETICS (2017)
Hypoxia is a Key Driver of Alternative Splicing in Human Breast Cancer Cells
Jian Han et al.
SCIENTIFIC REPORTS (2017)
A missense MT-ND5 mutation in differentiated Parkinson Disease cytoplasmic hybrid induces ROS-dependent DNA Damage Response amplified by DROSHA
Daniela Pignataro et al.
SCIENTIFIC REPORTS (2017)
Readers, writers and erasers of N6-methylated adenosine modification
Baixing Wu et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2017)
The role of alternative splicing in cancer
Babita Singh et al.
TRANSCRIPTION-AUSTIN (2017)
Exposure to high levels of fumarate and succinate leads to apoptotic cytotoxicity and altered global DNA methylation profiles in vitro
Johannes F. Wentzel et al.
BIOCHIMIE (2017)
Understanding the Intersections between Metabolism and Cancer Biology
Matthew G. Vander Heiden et al.
CELL (2017)
Elevated expression of JMJD6 is associated with oral carcinogenesis and maintains cancer stemness properties
Chang-Ryul Lee et al.
CARCINOGENESIS (2016)
TET-catalyzed oxidation of intragenic 5-methylcytosine regulates CTCF-dependent alternative splicing
Ryan J. Marina et al.
EMBO JOURNAL (2016)
Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes
Tuomas Laukka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Insulator dysfunction and oncogene activation in IDH mutant gliomas
William A. Flavahan et al.
NATURE (2016)
Modulation of PKM alternative splicing by PTBP1 promotes gemcitabine resistance in pancreatic cancer cells
S. Calabretta et al.
ONCOGENE (2016)
Targeting MYC in cancer therapy: RNA processing offers new opportunities
Cheryl M. Koh et al.
BIOESSAYS (2016)
Jumonji Domain Containing Protein 6 Is Decreased in Human Preeclamptic Placentas and Regulates sFLT-1 Splice Variant Production
Kirsten R. Palmer et al.
BIOLOGY OF REPRODUCTION (2016)
Splicing of Nascent RNA Coincides with Intron Exit from RNA Polymerase II
Fernando Carrillo Oesterreich et al.
CELL (2016)
Epigenomics meets splicing through the TETs and CTCF
Ryan J. Marina et al.
CELL CYCLE (2016)
The Emerging Hallmarks of Cancer Metabolism
Natalya N. Pavlova et al.
CELL METABOLISM (2016)
RNA splicing, cell signaling, and response to therapies
Cherine Abou Faycal et al.
CURRENT OPINION IN ONCOLOGY (2016)
Structure-function relationships of human JmjC oxygenases - demethylases versus hydroxylases
Suzana Markolovic et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2016)
Role of TET enzymes in DNA methylation, development, and cancer
Kasper Dindler Rasmussen et al.
GENES & DEVELOPMENT (2016)
A Novel Role for Pyruvate Kinase M2 as a Corepressor for P53 during the DNA Damage Response in Human Tumor Cells
Li Xia et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Defective control of pre-messenger RNA splicing in human disease
Benoit Chabot et al.
JOURNAL OF CELL BIOLOGY (2016)
Dynamic Histone Acetylation of H3K4me3 Nucleosome Regulates MCL1 Pre-mRNA Splicing
Dilshad H. Khan et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2016)
Treatment of infantile-onset spinal muscular atrophy with nusinersen: a phase 2, open-label, dose-escalation study
Richard S. Finkel et al.
LANCET (2016)
Nuclear m6A Reader YTHDC1 Regulates mRNA Splicing
Wen Xiao et al.
MOLECULAR CELL (2016)
Therapeutic targeting of splicing in cancer
Stanley Chun-Wei Lee et al.
NATURE MEDICINE (2016)
PCAF-mediated acetylation of transcriptional factor HOXB9 suppresses lung adenocarcinoma progression by targeting oncogenic protein JMJD6
Junhu Wan et al.
NUCLEIC ACIDS RESEARCH (2016)
m(6)A: Signaling for mRNA splicing
Samir Adhikari et al.
RNA BIOLOGY (2016)
Splicing-factor alterations in cancers
Olga Anczukow et al.
RNA (2016)
How Are Short Exons Flanked by Long Introns Defined and Committed to Splicing?
Dror Hollander et al.
TRENDS IN GENETICS (2016)
Small Molecule Modulators of Pre-mRNA Splicing in Cancer Therapy
Maayan Salton et al.
TRENDS IN MOLECULAR MEDICINE (2016)
Recent advances in dynamic m6A RNA modification
Guangchao Cao et al.
OPEN BIOLOGY (2016)
The epigenetic modifier JMJD6 is amplified in mammary tumors and cooperates with c-Myc to enhance cellular transformation, tumor progression, and metastasis
Olga Aprelikova et al.
CLINICAL EPIGENETICS (2016)
Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation
Xinde Zheng et al.
eLife (2016)
Altered metabolite levels in cancer: implications for tumour biology and cancer therapy
Lucas B. Sullivan et al.
NATURE REVIEWS CANCER (2016)
Regulation of Alternative Splicing Through Coupling with Transcription and Chromatin Structure
Shiran Naftelberg et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 84 (2015)
HNRNPA2B1 Is a Mediator of m6A-Dependent Nuclear RNA Processing Events
Claudio R. Alarcon et al.
CELL (2015)
2-Oxoglutarate-dependent dioxygenases are sensors of energy metabolism, oxygen availability, and iron homeostasis: potential role in the regulation of aging process
Antero Salminen et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2015)
Motor neuron cell-nonautonomous rescue of spinal muscular atrophy phenotypes in mild and severe transgenic mouse models
Yimin Hua et al.
GENES & DEVELOPMENT (2015)
A majority of m6A residues are in the last exons, allowing the potential for 3′ UTR regulation
Shengdong Ke et al.
GENES & DEVELOPMENT (2015)
Protein Hydroxylation Catalyzed by 2-Oxoglutarate-dependent Oxygenases
Suzana Markolovic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Increased Serine-Arginine (SR) Protein Phosphorylation Changes Pre-mRNA Splicing in Hypoxia
Egle Jakubauskiene et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond
Bogdan I. Fedeles et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Pyruvate Kinase Isoform Expression Alters Nucleotide Synthesis to Impact Cell Proliferation
Sophia Y. Lunt et al.
MOLECULAR CELL (2015)
Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex
Lanfeng Wang et al.
NATURE (2015)
The spliceosome is a therapeutic vulnerability in MYC-driven cancer
Tiffany Y. -T. Hsu et al.
NATURE (2015)
A lncRNA regulates alternative splicing via establishment of a splicing-specific chromatin signature
Inma Gonzalez et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Transcriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6
Yu-Jie Hu et al.
NUCLEIC ACIDS RESEARCH (2015)
The extended AT-hook is a novel RNA binding motif
Michael Filarsky et al.
RNA BIOLOGY (2015)
An alternative splicing event amplifies evolutionary differences between vertebrates
Serge Gueroussov et al.
SCIENCE (2015)
Pyruvate kinase: Function, regulation and role in cancer
William J. Israelsen et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2015)
The alternative role of DNA methylation in splicing regulation
Galit Lev Maor et al.
TRENDS IN GENETICS (2015)
Epigenetic regulation by histone demethylases in hypoxia
Rebecca L. Hancock et al.
EPIGENOMICS (2015)
A lncRNA regulates alternative splicing via establishment of a splicing-specific chromatin signature
Inma Gonzalez et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
HP1 Is Involved in Regulating the Global Impact of DNA Methylation on Alternative Splicing
Ahuvi Yearim et al.
CELL REPORTS (2015)
Role of JMJD6 in Breast Tumourigenesis
Coralie Poulard et al.
PLOS ONE (2015)
Mutational Hotspot of TET2, IDH1, IDH2, SRSF2, SF3B1, KRAS, and NRAS from Human Systemic Mastocytosis Are Not Conserved in Canine Mast Cell Tumors
Eleonora Zorzan et al.
PLOS ONE (2015)
No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis
Katharina Bluemlein et al.
Oncotarget (2015)
Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions
Hao Wu et al.
CELL (2014)
FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis
Xu Zhao et al.
CELL RESEARCH (2014)
Krebs cycle dysfunction shapes epigenetic landscape of chromatin: Novel insights into mitochondrial regulation of aging process
Antero Salminen et al.
CELLULAR SIGNALLING (2014)
Studies on the catalytic domains of multiple JmjC oxygenases using peptide substrates
Sophie T. Williams et al.
EPIGENETICS (2014)
Pre-mRNA splicing is facilitated by an optimal RNA polymerase II elongation rate
Nova Fong et al.
GENES & DEVELOPMENT (2014)
SRSF2-p95 hotspot mutation is highly associated with advanced forms of mastocytosis and mutations in epigenetic regulator genes
Katia Hanssens et al.
HAEMATOLOGICA (2014)
Dynamic changes in DNA methylation and hydroxymethylation when hES cells undergo differentiation toward a neuronal lineage
Mirang Kim et al.
HUMAN MOLECULAR GENETICS (2014)
Landscape of genetic lesions in 944 patients with myelodysplastic syndromes
T. Haferlach et al.
LEUKEMIA (2014)
A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation
Jianzhao Liu et al.
NATURE CHEMICAL BIOLOGY (2014)
Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain
Chao Xu et al.
NATURE CHEMICAL BIOLOGY (2014)
The centrosomal kinase NEK2 is a novel splicing factor kinase involved in cell survival
Chiara Naro et al.
NUCLEIC ACIDS RESEARCH (2014)
Jumonji domain containing protein 6 (Jmjd6) modulates splicing and specifically interacts with arginine-serine-rich (RS) domains of SR- and SR-like proteins
Astrid Heim et al.
NUCLEIC ACIDS RESEARCH (2014)
RNA-dependent chromatin localization of KDM4D lysine demethylase promotes H3K9me3 demethylation
Muhammad Zoabi et al.
NUCLEIC ACIDS RESEARCH (2014)
Hallmarks of alternative splicing in cancer
S. Oltean et al.
ONCOGENE (2014)
The alternative splicing side of cancer
Giuseppe Biamonti et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2014)
Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers
Shruti Desai et al.
ONCOTARGET (2014)
JMJD6 Promotes Colon Carcinogenesis through Negative Regulation of p53 by Hydroxylation
Feng Wang et al.
PLOS BIOLOGY (2014)
Genome-wide dynamics of Pol II elongation and its interplay with promoter proximal pausing, chromatin, and exons
Iris Jonkers et al.
ELIFE (2014)
The polyserine domain of the lysyl-5 hydroxylase Jmjd6 mediates subnuclear localization
Alexander Wolf et al.
BIOCHEMICAL JOURNAL (2013)
SDH Mutations Establish a Hypermethylator Phenotype in Paraganglioma
Eric Letouze et al.
CANCER CELL (2013)
Brd4 and JMJD6-Associated Anti-Pause Enhancers in Regulation of Transcriptional Pause Release
Wen Liu et al.
CELL (2013)
Dynamic Readers for 5-(Hydroxy)Methylcytosine and Its Oxidized Derivatives
Cornelia G. Spruijt et al.
CELL (2013)
PKM2 Isoform-Specific Deletion Reveals a Differential Requirement for Pyruvate Kinase in Tumor Cells
William J. Israelsen et al.
CELL (2013)
SR Proteins Collaborate with 7SK and Promoter-Associated Nascent RNA to Release Paused Polymerase
Xiong Ji et al.
CELL (2013)
The Mitochondrial Chaperone TRAP1 Promotes Neoplastic Growth by Inhibiting Succinate Dehydrogenase
Marco Sciacovelli et al.
CELL METABOLISM (2013)
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition
Alika K. Maunakea et al.
CELL RESEARCH (2013)
Pyruvate kinase M2 is highly correlated with the differentiation and the prognosis of esophageal squamous cell cancer
C. Zhan et al.
DISEASES OF THE ESOPHAGUS (2013)
Exploiting the bad eating habits of Ras-driven cancers
Eileen White
GENES & DEVELOPMENT (2013)
Reciprocal Regulation of Protein Kinase and Pyruvate Kinase Activities of Pyruvate Kinase M2 by Growth Signals
Xueliang Gao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Succinate dehydrogenase deficiency is associated with decreased 5-hydroxymethylcytosine production in gastrointestinal stromal tumors: implications for mechanisms of tumorigenesis
Emily F. Mason et al.
MODERN PATHOLOGY (2013)
ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility
Guanqun Zheng et al.
MOLECULAR CELL (2013)
TET enzymes, TDG and the dynamics of DNA demethylation
Rahul M. Kohli et al.
NATURE (2013)
TETonic shift: biological roles of TET proteins in DNA demethylation and transcription
William A. Pastor et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)
Alternative splicing: a pivotal step between eukaryotic transcription and translation
Alberto R. Kornblihtt et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)
Targeting cellular metabolism to improve cancer therapeutics
Y. Zhao et al.
CELL DEATH & DISEASE (2013)
When epigenetics meets alternative splicing: the roles of DNA methylation and GC architecture
Sahar Gelfman et al.
EPIGENOMICS (2013)
Misregulation of Pre-mRNA Alternative Splicing in Cancer
Jian Zhang et al.
CANCER DISCOVERY (2013)
A Role for Cytosolic Fumarate Hydratase in Urea Cycle Metabolism and Renal Neoplasia
Julie Adam et al.
CELL REPORTS (2013)
Pre-mRNA processing factors meet the DNA damage response
Alessandra Montecucco et al.
Frontiers in Genetics (2013)
Kinetic analysis of FTO (fat mass and obesity-associated) reveals that it is unlikely to function as a sensor for 2-oxoglutarate
Marcella Ma et al.
BIOCHEMICAL JOURNAL (2012)
Kinetic Analysis of Iron-Dependent Histone Demethylases: α-Ketoglutarate Substrate Inhibition and Potential Relevance to the Regulation of Histone Demethylation in Cancer Cells
Barbara Cascella et al.
BIOCHEMISTRY (2012)
Commonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin remodeling and splicing
Anna Dolnik et al.
BLOOD (2012)
PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis
Weiwei Yang et al.
CELL (2012)
Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors
Mengtao Xiao et al.
GENES & DEVELOPMENT (2012)
Changes in exon-intron structure during vertebrate evolution affect the splicing pattern of exons
Sahar Gelfman et al.
GENOME RESEARCH (2012)
Deep sequencing of subcellular RNA fractions shows splicing to be predominantly co-transcriptional in the human genome but inefficient for IncRNAs
Hagen Tilgner et al.
GENOME RESEARCH (2012)
Pyruvate Kinase M2 Regulates Gene Transcription by Acting as a Protein Kinase
Xueliang Gao et al.
MOLECULAR CELL (2012)
Serine is a natural ligand and allosteric activator of pyruvate kinase M2
Barbara Chaneton et al.
NATURE (2012)
ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect
Weiwei Yang et al.
NATURE CELL BIOLOGY (2012)
Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
Victor Quesada et al.
NATURE GENETICS (2012)
Molecular mechanisms and potential functions of histone demethylases
Susanne Marije Kooistra et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Concentration-dependent control of pyruvate kinase M mutually exclusive splicing by hnRNP proteins
Mo Chen et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
Overexpression of the M2 isoform of pyruvate kinase is an adverse prognostic factor for signet ring cell gastric cancer
Jae Yun Lim et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2012)
Exon-centric regulation of pyruvate kinase M alternative splicing via mutually exclusive exons
Zhenxun Wang et al.
JOURNAL OF MOLECULAR CELL BIOLOGY (2012)
Manipulation of PK-M mutually exclusive alternative splicing by antisense oligonucleotides
Zhenxun Wang et al.
OPEN BIOLOGY (2012)
Psip1/Ledgf p52 Binds Methylated Histone H3K36 and Splicing Factors and Contributes to the Regulation of Alternative Splicing
Madapura M. Pradeepa et al.
PLOS GENETICS (2012)
Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms
Luca Malcovati et al.
BLOOD (2011)
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
Weibo Luo et al.
CELL (2011)
Epigenetics in Alternative Pre-mRNA Splicing
Reini F. Luco et al.
CELL (2011)
Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells
Hao Wu et al.
GENES & DEVELOPMENT (2011)
Global impact of RNA polymerase II elongation inhibition on alternative splicing regulation
Joanna Y. Ip et al.
GENOME RESEARCH (2011)
Pyruvate kinase type M2: A key regulator of the metabolic budget system in tumor cells
Sybille Mazurek
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2011)
Inborn and acquired metabolic defects in cancer
Christian Frezza et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2011)
The Brd4 Extraterminal Domain Confers Transcription Activation Independent of pTEFb by Recruiting Multiple Proteins, Including NSD3
Shaila Rahman et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
Acetyl-CoA Induces Cell Growth and Proliferation by Promoting the Acetylation of Histones at Growth Genes
Ling Cai et al.
MOLECULAR CELL (2011)
CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing
Sanjeev Shukla et al.
NATURE (2011)
N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
Guifang Jia et al.
NATURE CHEMICAL BIOLOGY (2011)
Jumonji domain-containing protein 6 (Jmjd6) is required for angiogenic sprouting and regulates splicing of VEGF-receptor 1
Jes-Niels Boeckel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA
Yu-Fei He et al.
SCIENCE (2011)
Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses
Dimitrios Anastasiou et al.
SCIENCE (2011)
Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine
Shinsuke Ito et al.
SCIENCE (2011)
Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases
Christoph Loenarz et al.
TRENDS IN BIOCHEMICAL SCIENCES (2011)
Spliceosome Structure and Function
Cindy L. Will et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)
5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells
Hume Stroud et al.
GENOME BIOLOGY (2011)
The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate
Patrick S. Ward et al.
CANCER CELL (2010)
Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation
Maria E. Figueroa et al.
CANCER CELL (2010)
Structural studies on human 2-oxoglutarate dependent oxygenases
Michael A. McDonough et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2010)
Chromatin density and splicing destiny: on the cross-talk between chromatin structure and splicing
Schraga Schwartz et al.
EMBO JOURNAL (2010)
HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer
Charles J. David et al.
NATURE (2010)
Relationship between nucleosome positioning and DNA methylation
Ramakrishna K. Chodavarapu et al.
NATURE (2010)
Interaction of JMJD6 with single-stranded RNA
Xia Hong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism
Cynthia V. Clower et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Histone modification levels are predictive for gene expression
Rosa Karlic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
First come, first served revisited: Factors affecting the same alternative splicing event have different effects on the relative rates of intron removal
Manuel de la Mata et al.
RNA (2010)
Regulation of Alternative Splicing by Histone Modifications
Reini F. Luco et al.
SCIENCE (2010)
Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies
Omar Abdel-Wahab et al.
BLOOD (2009)
Antitumor effects of 2-oxoglutarate through inhibition of angiogenesis in a murine tumor model
Ken Matsumoto et al.
CANCER SCIENCE (2009)
An inducible change in Fox-1/A2BP1 splicing modulates the alternative splicing of downstream neuronal target exons
Ji-Ann Lee et al.
GENES & DEVELOPMENT (2009)
High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing
Emily Hodges et al.
GENOME RESEARCH (2009)
Predictive chromatin signatures in the mammalian genome
Gary C. Hon et al.
HUMAN MOLECULAR GENETICS (2009)
Chromatin Binding of SRp20 and ASF/SF2 and Dissociation from Mitotic Chromosomes Is Modulated by Histone H3 Serine 10 Phosphorylation
Rebecca J. Loomis et al.
MOLECULAR CELL (2009)
Biased Chromatin Signatures around Polyadenylation Sites and Exons
Noah Spies et al.
MOLECULAR CELL (2009)
Inactivation of the Fto gene protects from obesity
Julia Fischer et al.
NATURE (2009)
Acquired mutations in TET2 are common in myelodysplastic syndromes
Saskia M. C. Langemeijer et al.
NATURE GENETICS (2009)
Differential chromatin marking of introns and expressed exons by H3K36me3
Paulina Kolasinska-Zwierz et al.
NATURE GENETICS (2009)
Chromatin organization marks exon-intron structure
Schraga Schwartz et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Mutation in TET2 in Myeloid Cancers
Francois Delhommeau et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
7SK snRNP/P-TEFb couples transcription elongation with alternative splicing and is essential for vertebrate development
Matjaz Barboric et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Jmjd6 Catalyses Lysyl-Hydroxylation of U2AF65, a Protein Associated with RNA Splicing
Celia J. Webby et al.
SCIENCE (2009)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1α
Patrick J. Pollard et al.
BIOCHEMICAL JOURNAL (2008)
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
Heather R. Christofk et al.
NATURE (2008)
Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing
Qun Pan et al.
NATURE GENETICS (2008)
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
David R. Wise et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Recognition of trimethylated histone h3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing
Robert J. Sims et al.
MOLECULAR CELL (2007)
JMJD6 is a histone arginine demethylase
Bingsheng Chang et al.
SCIENCE (2007)
Evolution of nova-dependent splicing regulation in the brain
Nejc Jelen et al.
PLOS GENETICS (2007)
The human SWI/SNF subunit Brm is a regulator of alternative splicing
E Batsche et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)
Newly initiated RNA encounters a factor involved in splicing immediately upon emerging from within RNA polymerase II
A Ujvári et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The phosphatidylserine receptor from Hydra is a nuclear protein with potential Fe(II) dependent oxygenase activity -: art. no. 26
M Cikala et al.
BMC CELL BIOLOGY (2004)
Oxygen sensing by HIF hydroxylases
CJ Schofield et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
Transcriptional activators differ in their abilities to control alternative splicing
G Nogués et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion
HA Coller et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Share Paper
