Journal
JOURNAL OF ONCOLOGY
Volume 2011, Issue -, Pages -Publisher
HINDAWI LTD
DOI: 10.1155/2011/953469
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Funding
- Portuguese League Against Cancer (Liga Portuguesa Contra o Cancro-Nucleo Regional do Norte)
- Fernando Pessoa University
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This study aimed to characterize theHPV infection status in adolescents and young university women in Portugal. The distribution of HPV genotypes was evaluated by PCR DNA genotyping after self-sampling collection from 435 women of exfoliated cervical cells using a commercial kit. We observed an overall frequency of HPV infection of 11.5%. Furthermore, HPV DNA prevalence was 16.6%in those young women that self-declared as sexually active. The more frequently detected HPV types were 31, 16, 53, and 61. Statistical analysis identified median age (OR = 3.56; P = 0.001), the number of lifetime sexual partners ( OR = 4.50; P < 0.001), and years of sexual activity ( OR = 2.36; P = 0.008) as risk factors for HPV acquisition. Hence, our study revealed that oncogenic HPV infection is common in young asymptomatic women Portuguese women, with a history of 2-5 sexual partners and over 2 year of sexual activity. Moreover, these results demonstrate that HPV detection performed in self-collected samplesmay be important to appraise better preventive strategies and to monitorize the influence of vaccination programmes within different populations.
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