4.6 Review

Mechanisms Underlying the Action and Synergism of Trastuzumab and Pertuzumab in Targeting HER2-Positive Breast Cancer

Related references

Note: Only part of the references are listed.
Review Biotechnology & Applied Microbiology

Adding Pertuzumab to Trastuzumab and Taxanes in HER2 positive breast cancer

Jack Patrick Gleeson et al.

EXPERT OPINION ON BIOLOGICAL THERAPY (2018)

Review Oncology

Treatment of advanced HER2-positive breast cancer: 2018 and beyond

Noam Ponde et al.

CANCER TREATMENT REVIEWS (2018)

Article Medicine, Research & Experimental

Expansion of allogeneic NK cells with efficient antibody-dependent cell cytotoxicity against multiple tumors

Diego Sanchez-Martinez et al.

THERANOSTICS (2018)

Article Oncology

TNFα-Induced Mucin 4 Expression Elicits Trastuzumab Resistance in HER2-Positive Breast Cancer

Maria F. Mercogliano et al.

CLINICAL CANCER RESEARCH (2017)

Article Medicine, General & Internal

HER2-positive breast cancer

Sibylle Loibl et al.

LANCET (2017)

Article Medicine, General & Internal

Adjuvant Pertuzumab and Trastuzumab in Early HER2-Positive Breast Cancer

Gunter von Minckwitz et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Review Oncology

Advances in the management of HER2-positive early breast cancer

Jose Baselga et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2017)

Article Oncology

Blockade of CD112R and TIGIT signaling sensitizes human natural killer cell functions

Feng Xu et al.

CANCER IMMUNOLOGY IMMUNOTHERAPY (2017)

Article Multidisciplinary Sciences

Pertuzumab and trastuzumab: the rationale way to synergy

Sandrine Richard et al.

ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS (2016)

Review Oncology

The role of HER2, EGFR, and other receptor tyrosine kinases in breast cancer

Jennifer L. Hsu et al.

CANCER AND METASTASIS REVIEWS (2016)

Article Pharmacology & Pharmacy

Targeted therapy for breast cancer and molecular mechanisms of resistance to treatment

Guowei Gu et al.

CURRENT OPINION IN PHARMACOLOGY (2016)

Review Biochemistry & Molecular Biology

A Structural Perspective on the Regulation of the Epidermal Growth Factor Receptor

Erika Kovacs et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 84 (2015)

Review Medicine, Research & Experimental

Targeting HER2 for the Treatment of Breast Cancer

Mothaffar F. Rimawi et al.

ANNUAL REVIEW OF MEDICINE, VOL 66 (2015)

Article Medicine, General & Internal

Pertuzumab, Trastuzumab, and Docetaxel in HER2-Positive Metastatic Breast Cancer

Sandra M. Swain et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Review Pharmacology & Pharmacy

Emerging EGFR antagonists for breast cancer

Ana Lluch et al.

EXPERT OPINION ON EMERGING DRUGS (2014)

Review Oncology

P95 HER2 fragments and breast cancer outcome

Deniz Tural et al.

EXPERT REVIEW OF ANTICANCER THERAPY (2014)

Review Pharmacology & Pharmacy

The ErbB/HER family of protein-tyrosine kinases and cancer

Robert Roskoski

PHARMACOLOGICAL RESEARCH (2014)

Article Oncology

Epidermal Growth Factor Receptor Inhibitors: Coming of Age

Amit Mahipal et al.

CANCER CONTROL (2014)

Review Medicine, Research & Experimental

Use of Pertuzumab for the Treatment of HER2-Positive Metastatic Breast Cancer

Leticia De Mattos-Arruda et al.

ADVANCES IN THERAPY (2013)

Article Oncology

Oncogenic ERBB3 Mutations in Human Cancers

Bijay S. Jaiswal et al.

CANCER CELL (2013)

Article Oncology

Pertuzumab counteracts the inhibitory effect of ErbB2 on degradation of ErbB3

Malgorzata Magdalena Sak et al.

CARCINOGENESIS (2013)

Review Biochemistry & Molecular Biology

Cellular Functions Regulated by Phosphorylation of EGFR on Tyr845

Ken-ichi Sato

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)

Review Oncology

Drug Resistance and the Role of Combination Chemotherapy in Improving Patient Outcomes

Denise A. Yardley

INTERNATIONAL JOURNAL OF BREAST CANCER (2013)

Review Oncology

Role of epidermal growth factor receptor in breast cancer

Hiroko Masuda et al.

BREAST CANCER RESEARCH AND TREATMENT (2012)

Review Oncology

Treatment of HER2-positive breast cancer: current status and future perspectives

Carlos L. Arteaga et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2012)

Article Medicine, General & Internal

Trastuzumab Emtansine for HER2-Positive Advanced Breast Cancer

Sunil Verma et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Article Medicine, General & Internal

Pertuzumab plus Trastuzumab plus Docetaxel for Metastatic Breast Cancer

Jose Baselga et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Article Cell Biology

Function of ERBB4 is determined by alternative splicing

Ville Veikkolainen et al.

CELL CYCLE (2011)

Article Biochemistry & Molecular Biology

Up-regulation of miR-21 Mediates Resistance to Trastuzumab Therapy for Breast Cancer

Chang Gong et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Medicine, Research & Experimental

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

Brian D. Lehmann et al.

JOURNAL OF CLINICAL INVESTIGATION (2011)

Review Oncology

Immune Effects of Trastuzumab

Marianna Nuti et al.

JOURNAL OF CANCER (2011)

Review Oncology

Molecular Mechanisms of Trastuzumab Resistance in HER2 Overexpressing Breast Cancer

Gabriel L. Fiszman et al.

INTERNATIONAL JOURNAL OF BREAST CANCER (2011)

Article Biochemistry & Molecular Biology

Cell Signaling by Receptor Tyrosine Kinases

Mark A. Lemmon et al.

Review Oncology

Potential of ErbB4 antibodies for cancer therapy

Maija Hollmen et al.

FUTURE ONCOLOGY (2010)

Article Multidisciplinary Sciences

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation

Fumin Shi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Cell Biology

Targeting erbB receptors

Zheng Cai et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2010)

Review Oncology

Anti-epidermal growth factor receptor monoclonal antibodies in cancer treatment

Jaume Capdevila et al.

CANCER TREATMENT REVIEWS (2009)

Article Cell Biology

ErbB receptors and signaling pathways in cancer

Nancy E. Hynes et al.

CURRENT OPINION IN CELL BIOLOGY (2009)

Review Pharmacology & Pharmacy

ADAM17 as a Therapeutic Target in Multiple Diseases

Joaquin Arribas et al.

CURRENT PHARMACEUTICAL DESIGN (2009)

Review Oncology

Ligand-induced ErbB receptor dimerization

Mark A. Lemmon

EXPERIMENTAL CELL RESEARCH (2009)

Article Biochemistry & Molecular Biology

A Naturally Occurring HER2 Carboxy-Terminal Fragment Promotes Mammary Tumor Growth and Metastasis

Kim Pedersen et al.

MOLECULAR AND CELLULAR BIOLOGY (2009)

Review Pharmacology & Pharmacy

Functional selectivity of EGF family peptide growth factors: Implications for cancer

Kristy J. Wilson et al.

PHARMACOLOGY & THERAPEUTICS (2009)

Review Biophysics

Structure-based view of epidermal growth factor receptor regulation

Kathryn M. Ferguson

ANNUAL REVIEW OF BIOPHYSICS (2008)

Review Cell Biology

EGFR family: Structure physiology signalling and therapeutic targets

Antony W. Burgess

GROWTH FACTORS (2008)

Article Oncology

HER4 intracellular domain (4ICD) activity in the developing mammary gland and breast cancer

Frank E. Jones

JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA (2008)

Article Oncology

Expression of p95HER2, a truncated form of the HER2 receptor, and response to anti-HER2 therapies in breast cancer

Maurizio Scaltriti et al.

JOURNAL OF THE NATIONAL CANCER INSTITUTE (2007)

Article Biochemistry & Molecular Biology

Biosynthesis of tumorigenic HER2 C-terminal fragments by alternative initiation of translation

Judit Anido et al.

EMBO JOURNAL (2006)

Review Cell Biology

EGF-ERBB signalling: towards the systems level

Ami Citri et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)

Review Oncology

Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer

Rita Nahta et al.

NATURE CLINICAL PRACTICE ONCOLOGY (2006)

Review Pharmacology & Pharmacy

The ErbB receptors and their ligands in cancer: An overview

N Normanno et al.

CURRENT DRUG TARGETS (2005)

Review Oncology

ERBB receptors and cancer: The complexity of targeted inhibitors

NE Hynes et al.

NATURE REVIEWS CANCER (2005)

Article Biochemistry & Molecular Biology

TGFα expression impairs trastuzumab-induced HER2 downregulation

G Valabrega et al.

ONCOGENE (2005)

Article Biochemistry & Molecular Biology

Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity

BS Kochupurakkal et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Phosphotyrosine interactome of the ErbB-receptor kinase family

Waltraud X. Schulze et al.

MOLECULAR SYSTEMS BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Neuroglycan C, a novel member of the neuregulin family

Y Kinugasa et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)

Article Biochemical Research Methods

Purification of Her-2 extracellular domain and identification of its cleavage site

CX Yuan et al.

PROTEIN EXPRESSION AND PURIFICATION (2003)

Review Oncology

ErbB-4: mechanism of action and biology

G Carpenter

EXPERIMENTAL CELL RESEARCH (2003)

Article Multidisciplinary Sciences

Tumor biology - Herceptin acts as an anti-angiogenic cocktail

Y Izumi et al.

NATURE (2002)

Article Biochemistry & Molecular Biology

Heregulin-dependent activation of phosphoinositide 3-kinase and Akt via the ErbB2/ErbB3 co-receptor

NJ Hellyer et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Oncology

EGFR and cancer prognosis

RI Nicholson et al.

EUROPEAN JOURNAL OF CANCER (2001)

Review Cell Biology

Untangling the ErbB signalling network

Y Yarden et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2001)

Article Biochemistry & Molecular Biology

Akt/protein kinase B isoforms are differentially regulated by epidermal growth factor stimulation

J Okano et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)

Article Multidisciplinary Sciences

Molecular portraits of human breast tumours

CM Perou et al.

NATURE (2000)

Article Biochemistry & Molecular Biology

Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets

RA Clynes et al.

NATURE MEDICINE (2000)