Related references
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INCREASED mRNA EXPRESSION OF ADAMTS METALLOPROTEINASES IN METASTATIC FOCI OF HEAD AND NECK CANCER
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A Disintegrin-like and Metalloprotease (Reprolysin-type) with Thrombospondin Type 1 Motif (ADAMTS) Superfamily: Functions and Mechanisms
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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The ADAMTS12 metalloprotease gene is epigenetically silenced in tumor cells and transcriptionally activated in the stroma during progression of colon cancer
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JOURNAL OF CELL SCIENCE (2009)
ADAMTS9 activation by interleukin 1β via NFATc1 in OUMS-27 chondrosarcoma cells and in human chondrocytes
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MOLECULAR AND CELLULAR BIOCHEMISTRY (2009)
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ATHEROSCLEROSIS (2008)
The first but not the second thrombospondin type 1 repeat of ADAMTS5 functions as an angiogenesis inhibitor
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CANCER RESEARCH (2008)
Multimodal signaling by the ADAMTSs (a disintegrin and metalloproteinase with thrombospondin motifs) promotes neurite extension
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EXPERIMENTAL NEUROLOGY (2008)
Characterization of a novel epigenetically-silenced, growth-suppressive gene, ADAMTS9, and its association with lymph node metastases in nasopharyngeal carcinoma (Publication with Expression of Concern. See vol. 141, pg. 2368, 2017)
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INTERNATIONAL JOURNAL OF CANCER (2008)
Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulin
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OSTEOARTHRITIS AND CARTILAGE (2008)
Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5
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PROTEIN SCIENCE (2008)
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SCIENCE (2008)
The secreted metalloprotease ADAMTS20 is required for melanoblast survival
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PLOS GENETICS (2008)
High resolution crystal structure of the catalytic domain of ADAMTS-5 (aggrecanase-2)
Huey-Sheng Shieh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
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EUROPEAN CELLS & MATERIALS (2008)
Distinguishing aggrecan loss from aggrecan proteolysis in ADAMTS-4 and ADAMTS-5 single and double deficient mice
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JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Epigenetic identification of ADAMTS18 as a novel 16q23.1 tumor suppressor frequently silenced in esophageal, nasopharyngeal and multiple other carcinomas
H. Jin et al.
ONCOGENE (2007)
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SCIENCE (2007)
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PATHOLOGY INTERNATIONAL (2007)
Double-knockout of ADAMTS-4 and ADAMTS-5 in mice results in physiologically normal animals and prevents the progression of osteoarthritis
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ARTHRITIS AND RHEUMATISM (2007)
The ADAMTS12 metalloproteinase exhibits anti-tumorigenic properties through modulation of the Ras-dependent ERK signalling pathway
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JOURNAL OF CELL SCIENCE (2007)
TIMP-3 inhibition of ADAMTS-4 (Aggrecanase-1) is modulated by interactions between aggrecan and the C-terminal domain of ADAMTS-4
Gareth J. Wayne et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Anti-angiogenic peptides identified in thrombospondin type I domains
Emmanouil D. Karagiannis et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Proteolytic activities of human ADAMTS-5 - Comparative studies with ADAMTS-4
Christi Gendron et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Regulation of ADAMTS9 secretion and enzymatic activity by its propeptide
Bon-Hun Koo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Abnormal dentin structure in two novel gene mutations [COL1A1, Arg134Cys] and [ADAMTS2, Trp795-to-ter] causing rare type I collagen disorders
P. J. De Coster et al.
ARCHIVES OF ORAL BIOLOGY (2007)
Identification of a tumor suppressive critical region mapping to 3p14.2 in esophageal squamous cell carcinoma and studies of a candidate tumor suppressor gene, ADAMTS9
P. H. Y. Lo et al.
ONCOGENE (2007)
The role of von Willebrand factor in thrombus formation
Zaverio M. Ruggeri
THROMBOSIS RESEARCH (2007)
ADAMTS1 is regulated by interleukin-1 beta, not by hypoxia, in chondrosarcoma
Thomas Kalinski et al.
HUMAN PATHOLOGY (2007)
ADAMTS1 mediates the release of antiangiogenic polypeptides from TSP1 and 2
Nathan V. Lee et al.
EMBO JOURNAL (2006)
The consensus coding sequences of human breast and colorectal cancers
Tobias Sjoeblom et al.
SCIENCE (2006)
Vascular endothelial growth factor upregulates expression of ADAMTS1 in endothelial cells through protein kinase C signaling
Zhenhua Xu et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2006)
An alternative spliced transcript of ADAMTS4 is present in human synovium from OA patients
Shane D. Wainwright et al.
MATRIX BIOLOGY (2006)
Activation by IL-1 of bovine articular chondrocytes in culture within a 3D collagen-based scaffold.: An in vitro model to address the effect of compounds with therapeutic potential in osteoarthritis
D. Cortial et al.
OSTEOARTHRITIS AND CARTILAGE (2006)
ADAMTS1 interacts with, cleaves, and modifies the extracellular location of the matrix inhibitor tissue factor pathway inhibitor-2
Antoni X. Torres-Collado et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Regulation of the human ADAMTS-4 promoter by transcription factors and cytokines
Kannan Thirunavukkarasu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein
Chuan-ju Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Human endothelial cells synthesize and release ADAMTS-13
N. Turner et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2006)
Cell-surface processing of pro-ADAMTS9 by furin
BH Koo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Expression of ADAMTS-8, a secreted protease with antiangiogenic properties, is downregulated in brain tumours
JR Dunn et al.
BRITISH JOURNAL OF CANCER (2006)
Complete deficiency in ADAMTS13 is prothrombotic, but it alone is not sufficient to cause thrombotic thrombocytopenic purpura
F Banno et al.
BLOOD (2006)
Full-length ADAMTS-1 and the ADAMTS-1 fragments display pro- and antimetastatic activity, respectively
YJ Liu et al.
ONCOGENE (2006)
Identification of substrates of the extracellular protease ADAMTS1 by DIGE proteomic analysis
Francesc Canals et al.
PROTEOMICS (2006)
Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: Comparative analyses with ADAMTS-5,-9,-16 and-18
WL Zeng et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2006)
ADAMTS8 and ADAMTS15 expression predicts survival in human breast carcinoma
S Porter et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
Matrix-degrading proteases ADAMTS4 and ADAMTS5 (disintegrins and metalloproteinases with thrombospondin motifs 4 and 5) are expressed in human glioblastomas
J Held-Feindt et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
Platelet-derived VWF-cleaving metalloprotease ADAMTS-13
L Liu et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2005)
Domains and maturation processes that regulate the activity of ADAMTS-2, a metalloproteinase cleaving the aminopropeptide of fibrillar procollagens types I-III and V
A Colige et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Fibulin-1 acts as a cofactor for the matrix metalloprotease ADAMTS-1
NV Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Shigatoxin triggers thrombotic thrombocytopenic purpura in genetically susceptible ADAMTS13-deficient mice
DG Motto et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Human glioblastomas overexpress ADAMTS-5 that degrades brevican
M Nakada et al.
ACTA NEUROPATHOLOGICA (2005)
Localization of ADAMTS 13 to the stellate cells of human liver
M Uemura et al.
BLOOD (2005)
ADAMTS1 proteinase is up-regulated in wounded skin and regulates migration of fibroblasts and endothelial cells
M Krampert et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Binding of ADAMTS13 to von Willebrand factor
EM Majerus et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
ADAMTS13 is expressed in hepatic stellate cells
WH Zhou et al.
LABORATORY INVESTIGATION (2005)
Adamts9 is widely expressed during mouse embryo development
KA Jungers et al.
GENE EXPRESSION PATTERNS (2005)
The expression and regulation of ADAMTS-1, -4, -5, -9, and -15, and TIMP-3 by TGFβ1 in prostate cells:: Relevance to the accumulation of versican
NA Cross et al.
PROSTATE (2005)
Regulated expression of ADAMTS family members in follicles and cumulus oocyte complexes: Evidence for specific and redundant patterns during ovulation
JS Richards et al.
BIOLOGY OF REPRODUCTION (2005)
ADAMTS-1-knockout mice do not exhibit abnormalities in aggrecan turnover in vitro or in vivo
CB Little et al.
ARTHRITIS AND RHEUMATISM (2005)
ADAMTS-9 is synergistically induced by interleukin-1β and tumor necrosis factor α in OUMS-27 chondrosarcoma cells and in human chondrocytes
K Demircan et al.
ARTHRITIS AND RHEUMATISM (2005)
Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis
SS Glasson et al.
NATURE (2005)
ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro
H Stanton et al.
NATURE (2005)
The ADAMTS metalloproteinases
S Porter et al.
BIOCHEMICAL JOURNAL (2005)
Proprotein convertase furin interacts with and cleaves pro-ADAMTS4 (aggrecanase-1) in the trans-Golgi network
P Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Dysregulated expression of adamalysin-thrombospondin genes in human breast carcinoma
S Porter et al.
CLINICAL CANCER RESEARCH (2004)
Effects of transforming growth factor-β on aggrecanase production and proteoglycan degradation by human chondrocytes in vitro
N Moulharat et al.
OSTEOARTHRITIS AND CARTILAGE (2004)
Adamts-1 is essential for the development and function of the urogenital system
L Mittaz et al.
BIOLOGY OF REPRODUCTION (2004)
ADAMTS4 (aggrecanase-1) activation on the cell surface involves C-terminal cleavage by glycosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan sulfate on syndecan-1
G Gao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Novel types of mutation responsible for the dermatosparactic type of Ehlers-Danlos syndrome (type VIIC) and common polymorphisms in the ADAMTS2 gene
A Colige et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2004)
METH-2 silencing and promoter hypermethylation in NSCLC
JR Dunn et al.
BRITISH JOURNAL OF CANCER (2004)
Identification of prodomain determinants involved in ADAMTS-1 biosynthesis
JM Longpré et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Effect of adenovirus-mediated overexpression of bovine ADAMTS-4 and human ADAMTS-5 in primary bovine articular chondrocyte pellet culture system
M Arai et al.
OSTEOARTHRITIS AND CARTILAGE (2004)
Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice
SS Glasson et al.
ARTHRITIS AND RHEUMATISM (2004)
The carboxyl-terminal half region of ADAMTS-1 suppresses both tumorigenicity and experimental tumor metastatic potential
K Kuno et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage
LA Collins-Racie et al.
MATRIX BIOLOGY (2004)
Dynamic induction of ADAMTS1 gene in the early phase of acute myocardial infarction
K Nakamura et al.
JOURNAL OF BIOCHEMISTRY (2004)
Cleavage of the ADAMTS13 propeptide is not required for protease activity
EM Majerus et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
ADAMTS1/METH1 inhibits endothelial cell proliferation by direct binding and sequestration of VEGF165
A Luque et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Transforming growth factor-β induces secretion of activated ADAMTS-2 -: A procollagen IIIN-proteinase
WM Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Expression of ADAMTS metalloproteinases in the retinal pigment epithelium derived cell line ARPE-19:: transcriptional regulation by TNFα
DJ Bevitt et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION (2003)
Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1
RPT Somerville et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Aggrecanases and cartilage matrix degradation
H Nagase et al.
ARTHRITIS RESEARCH & THERAPY (2003)
Induction of aggrecanase 1 (ADAM-TS4) by interleukin-1 occurs through activation of constitutively produced protein
MA Pratta et al.
ARTHRITIS AND RHEUMATISM (2003)
ADAMTS-13 activity in patients with brain and prostate tumors is mildly reduced, but not correlated to stage of malignancy and metastasis
M Bohm et al.
THROMBOSIS RESEARCH (2003)
Cloning, expression, and functional characterization of the von Willebrand factor-cleaving protease (ADAMTS13)
B Plaimauer et al.
BLOOD (2002)
Autocatalytic cleavage of ADAMTS-4 (Aggrecanase-1) reveals multiple glycosaminoglycan-binding sites
CR Flannery et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Expression profiling of primary non-small cell lung cancer for target identification
J Heighway et al.
ONCOGENE (2002)
Expression of ADAMTS1 during murine development
SNM Thai et al.
MECHANISMS OF DEVELOPMENT (2002)
The modulation of matrix metalloproteinase and ADAM gene expression in human chondrocytes by interleukin-1 and oncostatin M - A time-course study using real-time quantitative reverse transcription-polymerase chain reaction
PJT Koshy et al.
ARTHRITIS AND RHEUMATISM (2002)
Deficiency of von Willebrand factor-cleaving protease activity in the plasma of malignant patients
BH Koo et al.
THROMBOSIS RESEARCH (2002)
Expression and regulation of aggrecanase in arthritis:: The role of TGF-β
Y Yamanishi et al.
JOURNAL OF IMMUNOLOGY (2002)
Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains
S Cal et al.
GENE (2002)
A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-1 null mutant mice develop renal lesions mimicking obstructive nephropathy
H Yokoyama et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2002)
Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura
XL Zheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura
GG Levy et al.
NATURE (2001)
Purification of human von Willebrand factor-cleaving protease and its identification as a new member of the metalloproteinase family
K Fujikawa et al.
BLOOD (2001)
Partial amino acid sequence of purified von Willebrand factor-cleaving protease
HE Gerritsen et al.
BLOOD (2001)
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MD Tortorella et al.
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S Cal et al.
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TIMP-3 is a potent inhibitor of aggrecanase 1 (ADAM-TS4) and aggrecanase 2 (ADAM-TS5)
M Kashiwagi et al.
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Versican V1 proteolysis in human aorta in vivo occurs at the Glu441-Ala442 bond, a site that is cleaved by recombinant ADAMTS-1 and ADAMTS-4
JD Sandy et al.
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Transgenic mice with inactive alleles for procollagen N-proteinase (ADAMTS-2) develop fragile skin and male sterility
SW Li et al.
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Inhibition of ADAMTS4 (aggrecanase-1) by tissue inhibitors of metalloproteinases (TIMP-1, 2, 3 and 4)
G Hashimoto et al.
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ME Clark et al.
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B Caterson et al.
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RT Matthews et al.
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Sites of aggrecan cleavage by recombinant human aggrecanase-1 (ADAMTS-4)
MD Tortorella et al.
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Gene expression profiling in an in vitro model of angiogenesis
J Kahn et al.
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T Shindo et al.
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