Related references
Note: Only part of the references are listed.Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma
Genevieve Schindler et al.
ACTA NEUROPATHOLOGICA (2011)
Angiogenesis and invasion in glioma
Manabu Onishi et al.
BRAIN TUMOR PATHOLOGY (2011)
Neuro-oncology: continuing multidisciplinary progress
Motoo Nagane
LANCET NEUROLOGY (2011)
Isocitrate dehydrogenase-1 mutations: a fundamentally new understanding of diffuse glioma?
Nanne K. Kloosterhof et al.
LANCET ONCOLOGY (2011)
Angiogenesis in glioblastoma: just another moving target?
Michael Weller
BRAIN (2010)
A new alternative mechanism in glioblastoma vascularization: tubular vasculogenic mimicry
Soufiane El Hallani et al.
BRAIN (2010)
Exciting New Advances in Neuro-Oncology The Avenue to a Cure for Malignant Glioma
Erwin G. Van Meir et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2010)
Loss of ATM/Chk2/p53 Pathway Components Accelerates Tumor Development and Contributes to Radiation Resistance in Gliomas
Massimo Squatrito et al.
CANCER CELL (2010)
Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
Roel G. W. Verhaak et al.
CANCER CELL (2010)
Targeting SRC in glioblastoma tumors and brain metastases Rationale and preclinical studies
Manmeet S. Ahluwalia et al.
CANCER LETTERS (2010)
microRNA-34a is tumor suppressive in brain tumors and glioma stem cells
Fadila Guessous et al.
CELL CYCLE (2010)
An RNAi Screen Identifies TRRAP as a Regulator of Brain Tumor-Initiating Cell Differentiation
Heiko Wurdak et al.
CELL STEM CELL (2010)
Perivascular Nitric Oxide Activates Notch Signaling and Promotes Stem-like Character in PDGF-Induced Glioma Cells
Nikki Charles et al.
CELL STEM CELL (2010)
2010: neuro-oncology is moving!
Roger Stupp et al.
CURRENT OPINION IN NEUROLOGY (2010)
Phase I/IIa Study of Cilengitide and Temozolomide With Concomitant Radiotherapy Followed by Cilengitide and Temozolomide Maintenance Therapy in Patients With Newly Diagnosed Glioblastoma
Roger Stupp et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics
Camilla Krakstad et al.
MOLECULAR CANCER (2010)
Neurofibromatosis Type 1 and tumorigenesis: molecular mechanisms and therapeutic implications
Oren N. Gottfried et al.
NEUROSURGICAL FOCUS (2010)
Crosstalk Between the PI3K/mTOR and MEK/ERK Pathways Involved in the Maintenance of Self-Renewal and Tumorigenicity of Glioblastoma Stem-Like Cells
Jun Sunayama et al.
STEM CELLS (2010)
Targeting A20 Decreases Glioma Stem Cell Survival and Tumor Growth
Anita B. Hjelmeland et al.
PLOS BIOLOGY (2010)
Selective acquisition of IDH1 R132C mutations in astrocytomas associated with Li-Fraumeni syndrome
Takuya Watanabe et al.
ACTA NEUROPATHOLOGICA (2009)
IDH1 Mutations Are Early Events in the Development of Astrocytomas and Oligodendrogliomas
Takuya Watanabe et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
Duplication of 7q34 in Pediatric Low-Grade Astrocytomas Detected by High-Density Single-Nucleotide Polymorphism-Based Genotype Arrays Results in a Novel BRAF Fusion Gene
Angela J. Sievert et al.
BRAIN PATHOLOGY (2009)
Multicentre phase II studies evaluating imatinib plus hydroxyurea in patients with progressive glioblastoma
D. A. Reardon et al.
BRITISH JOURNAL OF CANCER (2009)
Genetic alterations and signaling pathways in the evolution of gliomas
Hiroko Ohgaki et al.
CANCER SCIENCE (2009)
IDH1 Mutations as Molecular Signature and Predictive Factor of Secondary Glioblastomas
Sumihito Nobusawa et al.
CLINICAL CANCER RESEARCH (2009)
Taking the time to make important decisions: The checkpoint effector kinases Chk1 and Chk2 and the DNA damage response
Travis H. Stracker et al.
DNA REPAIR (2009)
Brain angiogenesis in developmental and pathological processes: therapeutic aspects of vascular endothelial growth factor
Masabumi Shibuya
FEBS JOURNAL (2009)
Tumour angiogenesis: Its mechanism and therapeutic implications in malignant gliomas
Michael L. H. Wong et al.
JOURNAL OF CLINICAL NEUROSCIENCE (2009)
Randomized Phase II Trial of Erlotinib Versus Temozolomide or Carmustine in Recurrent Glioblastoma: EORTC Brain Tumor Group Study 26034
Martin J. van den Bent et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
The Neuronal MicroRNA miR-326 Acts in a Feedback Loop with Notch and Has Therapeutic Potential against Brain Tumors
Benjamin Kefas et al.
JOURNAL OF NEUROSCIENCE (2009)
BMI1 Sustains Human Glioblastoma Multiforme Stem Cell Renewal
Mohamed Abdouh et al.
JOURNAL OF NEUROSCIENCE (2009)
Age as a Predictive Factor in Glioblastomas: Population-Based Study
Daisuke Kita et al.
NEUROEPIDEMIOLOGY (2009)
Antiangiogenic Strategies for Treatment of Malignant Gliomas
Andrew S. Chi et al.
NEUROTHERAPEUTICS (2009)
IDH1 and IDH2 Mutations in Gliomas
Hai Yan et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Angiogenesis as a Therapeutic Target in Malignant Gliomas
Andrew S. Chi et al.
ONCOLOGIST (2009)
FDA Drug Approval Summary: Bevacizumab (Avastin (R)) as Treatment of Recurrent Glioblastoma Multiforme
Martin H. Cohen et al.
ONCOLOGIST (2009)
Absence of AKT1 Mutations in Glioblastoma
Fonnet E. Bleeker et al.
PLOS ONE (2009)
Perifosine: Update on a Novel Akt Inhibitor
Joell J. Gills et al.
CURRENT ONCOLOGY REPORTS (2009)
JSI-124 inhibits glioblastoma multiforme cell proliferation through G2/M cell cycle arrest and apoptosis augment
Yuhang Su et al.
CANCER BIOLOGY & THERAPY (2008)
Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells
Jeongwu Lee et al.
CANCER CELL (2008)
Novel anti-angiogenic therapies for malignant gliomas
Andrew D. Norden et al.
LANCET NEUROLOGY (2008)
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
L. Chin et al.
NATURE (2008)
NF-kappa B controls growth of glioblastomas/astrocytomas
Denise Smith et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2008)
Uncovering therapeutic targets for glioblastoma - A systems biology approach
Paul H. Huang et al.
CELL CYCLE (2007)
Malignant astrocytic glioma: genetics, biology, and paths to treatment
Frank B. Furnari et al.
GENES & DEVELOPMENT (2007)
Bevacizumab plus irinotecan in recurrent glioblastoma multiforme
James J. Vredenburgh et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies
Jayne M. Stommel et al.
SCIENCE (2007)
MicroRNA-21 knockdown disrupts glioma growth In vivo and displays synergistic cytotoxicity with neural precursor cell-delivered S-TRAIL in human gliomas
Maarten F. Corsten et al.
CANCER RESEARCH (2007)
Genetic pathways to primary and secondary glioblastoma
Hiroko Ohgaki et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
Recent developments in neurofibromatosis type 1
Ming-Jen Lee et al.
CURRENT OPINION IN NEUROLOGY (2007)
Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma
Keith L. Ligon et al.
NEURON (2007)
High TGFβ-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene
Alejandra Bruna et al.
CANCER CELL (2007)
Molecular targets of glioma invasion
M. Nakada et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2007)
Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma
Eli E. Bar et al.
STEM CELLS (2007)
PIK3CA alterations in primary (de novo) and secondary glioblastomas
Daisuke Kita et al.
ACTA NEUROPATHOLOGICA (2007)
Opinion - Angiogenesis: an organizing principle for drug discovery?
Judah Folkman
NATURE REVIEWS DRUG DISCOVERY (2007)
Notch signalling regulates stem cell numbers in vitro and in vivo
Andreas Androutsellis-Theotokis et al.
NATURE (2006)
Frequent alterations in the expression of serine/threonine kinases in human cancers
Maria Capra et al.
CANCER RESEARCH (2006)
PDGFRα-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling
Erica L. Jackson et al.
NEURON (2006)
Development of NG2 neural progenitor cells requires Olig gene function
Keith L. Ligon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival
P Vajkoczy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Discoidin domain receptor-1a (DDR1a) promotes glioma cell invasion and adhesion in association with matrix metalloproteinase-2
R Ram et al.
JOURNAL OF NEURO-ONCOLOGY (2006)
Differential gene expression analysis reveals generation of an autocrine loop by a mutant epidermal growth factor receptor in glioma cells
DB Ramnarain et al.
CANCER RESEARCH (2006)
Phase II study of imatinib mesylate plus hydroxyurea in adults with recurrent glioblastorna multiforme
DA Reardon et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors
IK Mellinghoff et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Inhibition of Rho-kinase affects astrocytoma morphology, motility, and invasion through activation of Rac1
B Salhia et al.
CANCER RESEARCH (2005)
Mechanisms of disease: Neural stem cells and the origin of gliomas
N Sanai et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Intracellular signal transduction pathway proteins as targets for cancer therapy
AA Adjei et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: A north central cancer treatment group study
E Galanis et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme
SM Chang et al.
INVESTIGATIONAL NEW DRUGS (2005)
CHEK2 mutations in primary glioblastomas
SL Sallinen et al.
JOURNAL OF NEURO-ONCOLOGY (2005)
Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib
DA Haas-Kogan et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2005)
Apoptosis and proliferation: correlation with p53 in astrocytic tumours
C Sarkar et al.
JOURNAL OF NEURO-ONCOLOGY (2005)
HER2 overexpression increases sensitivity to gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, through inhibition of HER2/HER3 heterodimer formation in lung cancer cells
A Hirata et al.
CANCER RESEARCH (2005)
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
R Stupp et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Prognostic effect of epidermal growth factor receptor and EGFRvIII in glioblastoma multiforme patients
AB Heimberger et al.
CLINICAL CANCER RESEARCH (2005)
Mutation analysis of B-RAF gene in human gliomas
D Basto et al.
ACTA NEUROPATHOLOGICA (2005)
High frequency of mutations of the PIK3CA gene in human cancers
Y Samuels et al.
SCIENCE (2004)
IL-6 is required for glioma development in a mouse model
J Weissenberger et al.
ONCOGENE (2004)
Inhibiting the phosphoinositide 3-kinase pathway for cancer treatment
P Workman
BIOCHEMICAL SOCIETY TRANSACTIONS (2004)
Predominant expression of mutant EGFR (EGFRvIII) is rare in primary glioblastomas
W Biernat et al.
BRAIN PATHOLOGY (2004)
Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
R Galli et al.
CANCER RESEARCH (2004)
Mechanism and biological significance of CD44 cleavage
O Nagano et al.
CANCER SCIENCE (2004)
Identification of human brain tumour initiating cells
SK Singh et al.
NATURE (2004)
Role of synaptojanin 2 in glioma cell migration and invasion
YY Chuang et al.
CANCER RESEARCH (2004)
Genetic pathways to glioblastoma:: A population-based study
H Ohgaki et al.
CANCER RESEARCH (2004)
Cancerous stem cells can arise from pediatric brain tumors
HD Hemmati et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Angiopoietin-2 induces human glioma invasion through the activation of matrix metalloprotease-2
B Hu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Molecular mechanisms of glioma invasiveness: The role of proteases
JS Rao
NATURE REVIEWS CANCER (2003)
Receptor tyrosine kinase signaling in gliomagenesis - Pathobiology and therapeutic approaches
GS Kapoor et al.
CANCER BIOLOGY & THERAPY (2003)
Malignant glioma physiology: cellular response to hypoxia and its role in tumor progression. (vol 138, pg 659, 2003)
DJ Brat et al.
ANNALS OF INTERNAL MEDICINE (2003)
Mitogenic signaling cascades in glial tumors
GS Kapoor et al.
NEUROSURGERY (2003)
Intracavitary VEGF, bFGF, IL-8, IL-12 levels in primary and recurrent malignant glioma
A Salmaggi et al.
JOURNAL OF NEURO-ONCOLOGY (2003)
Chk1 and Chk2 kinases in checkpoint control and cancer
J Bartek et al.
CANCER CELL (2003)
Malignant glioma physiology: Cellular response to hypoxia and its role in tumor progression
DJ Brat et al.
ANNALS OF INTERNAL MEDICINE (2003)
ATM and related protein kinases: Safeguarding genome integrity
Y Shiloh
NATURE REVIEWS CANCER (2003)
Rho GTPases in cell biology
S Etienne-Manneville et al.
NATURE (2002)
Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro
TN Ignatova et al.
GLIA (2002)
Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner
A Hirao et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
The phosphatidylinositol 3-kinase-AKT pathway in human cancer
I Vivanco et al.
NATURE REVIEWS CANCER (2002)
Proteolytic cleavage of the CD44 adhesion molecule in multiple human tumors
I Okamoto et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
CD44 expression in human gliomas
SM Ranuncolo et al.
JOURNAL OF SURGICAL ONCOLOGY (2002)
Molecular characterization of cell substratum attachments in human glial tumors relates to prognostic features
N Belot et al.
GLIA (2001)
EGFR overexpression and radiation response in glioblastoma multiforme
FG Barker et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2001)
Receptor tyrosine kinase signalling as a target for cancer intervention strategies
E Zwick et al.
ENDOCRINE-RELATED CANCER (2001)
PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme
JS Smith et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2001)
DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?
D Durocher et al.
CURRENT OPINION IN CELL BIOLOGY (2001)
Glioma cell motility is associated with reduced transcription of proapoptotic and proliferation genes: a cDNA microarray analysis
L Mariani et al.
JOURNAL OF NEURO-ONCOLOGY (2001)
p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage
C Chao et al.
EMBO JOURNAL (2000)
Chromosomal instability and p53 inactivation are required for genesis of glioblastoma but not for colorectal cancer in patients with germline mismatch repair gene mutation
SY Leung et al.
ONCOGENE (2000)
Mechanisms of disease:: Role of transforming growth factor β in human disease.
GC Blobe et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)
DNA damage-induced activation of p53 by the checkpoint kinase Chk2
A Hirao et al.
SCIENCE (2000)
Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice
EC Holland et al.
NATURE GENETICS (2000)
Share Paper
