Journal
TRANSLATIONAL NEURODEGENERATION
Volume 1, Issue -, Pages -Publisher
BIOMED CENTRAL LTD
DOI: 10.1186/2047-9158-1-14
Keywords
Neurotrophin; Neurotrophic factor; BDNF; NGF; Gene delivery; Mimetics
Categories
Funding
- NIH Neuroplasticity of Aging Predoctoral Training Grant
- UCSD NIH ADRC Pilot Grant
- LLHF
- DSRTF
Ask authors/readers for more resources
Neurotrophic factors are best known for their roles in both development and continued maintenance of the nervous system. Their strong potential to elicit pro-survival and pro-functional responses in neurons of the peripheral and central nervous system make them good drug candidates for treatment of a multitude of neurodegenerative disorders. However, significant obstacles remain and need to be overcome before translating the potential of neurotrophins into the therapeutic arena. This article addresses current efforts and advances in resolving these challenges and provides an overview of roadmaps for future translational research and neurotrophin-based drug developments.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available