Journal
ACTA PHARMACEUTICA SINICA B
Volume 4, Issue 1, Pages 18-25Publisher
INST MATERIA MEDICA, CHINESE ACAD MEDICAL SCIENCES
DOI: 10.1016/j.apsb.2013.11.001
Keywords
Solid dispersion; Poorly soluble drug; Phase separation; Drug-polymer interaction
Categories
Funding
- National Natural Science Foundation of China [50873056]
Ask authors/readers for more resources
The solid dispersion has become an established solubilization technology for poorly water soluble drugs. Since a solid dispersion is basically a drug-polymer two-component system, the drug-polymer interaction is the determining factor in its design and performance. In this review, we summarize our current understanding of solid dispersions both in the solid state and in dissolution, emphasizing the fundamental aspects of this important technology. (C) 2014 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available