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A software-programmable microfluidic device for automated biology
Luis M. Fidalgo et al.
LAB ON A CHIP (2011)
Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome
Masayuki Yazawa et al.
NATURE (2011)
A microfluidic array for large-scale ordering and orientation of embryos
Kwanghun Chung et al.
NATURE METHODS (2011)
Human Engineered Heart Tissue as a Versatile Tool in Basic Research and Preclinical Toxicology
Sebastian Schaaf et al.
PLOS ONE (2011)
From 3D cell culture to organs-on-chips
Dongeun Huh et al.
TRENDS IN CELL BIOLOGY (2011)
Convenient Method for Modifying Poly(dimethylsiloxane) To Be Airtight and Resistive against Absorption of Small Molecules
Kangning Ren et al.
ANALYTICAL CHEMISTRY (2010)
A microfluidic hepatic coculture platform for cell-based drug metabolism studies
Eric Novik et al.
BIOCHEMICAL PHARMACOLOGY (2010)
SPENDING ON NEW DRUG DEVELOPMENT
Christopher Paul Adams et al.
HEALTH ECONOMICS (2010)
A microfluidic platform for probing small artery structure and function
Axel Guenther et al.
LAB ON A CHIP (2010)
A multi-layer microfluidic device for efficient culture and analysis of renal tubular cells
Kyung-Jin Jang et al.
LAB ON A CHIP (2010)
Dynamics of Liquid Plugs of Buffer and Surfactant Solutions in a Micro-Engineered.Pulmonary Airway Model
Hossein Tavana et al.
LANGMUIR (2010)
Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
Xonia Carvajal-Vergara et al.
NATURE (2010)
How to improve R&D productivity: the pharmaceutical industry's grand challenge
Steven M. Paul et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Achieving pluripotency
Kim Baumann
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome.
Alessandra Moretti et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Correction: Mapping Proprioception across a 2D Horizontal Workspace
Elizabeth T. Wilson et al.
PLoS One (2010)
Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures
Alexander Ploss et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Reconstituting Organ-Level Lung Functions on a Chip
Dongeun Huh et al.
SCIENCE (2010)
Parylene-coating in PDMS microfluidic channels prevents the absorption of fluorescent dyes
Hirotaka Sasaki et al.
SENSORS AND ACTUATORS B-CHEMICAL (2010)
Synthesis and characterization of a biodegradable elastomer featuring a dual crosslinking mechanism
Richard T. Tran et al.
SOFT MATTER (2010)
Tissue engineering by self-assembly and bio-printing of living cells
Karoly Jakab et al.
BIOFABRICATION (2010)
Evaluation of a microfluidic based cell culture platform with primary human hepatocytes for the prediction of hepatic clearance in human
P. Chao et al.
BIOCHEMICAL PHARMACOLOGY (2009)
Microfeature guided skeletal muscle tissue engineering for highly organized 3-dimensional free-standing constructs
Mai T. Lam et al.
BIOMATERIALS (2009)
Scaffold-free vascular tissue engineering using bioprinting
Cyrille Norotte et al.
BIOMATERIALS (2009)
Development of high throughput optical sensor array for on-line pH monitoring in micro-scale cell culture environment
Min-Hsien Wu et al.
BIOMEDICAL MICRODEVICES (2009)
A Novel System for Evaluation of Drug Mixtures for Potential Efficacy in Treating Multidrug Resistant Cancers
Daniel A. Tatosian et al.
BIOTECHNOLOGY AND BIOENGINEERING (2009)
Characterization of a Gastrointestinal Tract Microscale Cell Culture Analog Used to Predict Drug Toxicity
Gretchen J. Mahler et al.
BIOTECHNOLOGY AND BIOENGINEERING (2009)
Pluripotent Stem Cells and Disease Modeling
Alan Colman et al.
CELL STEM CELL (2009)
Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease
Krishanu Saha et al.
CELL STEM CELL (2009)
Comparative Proteomic Phenotyping of Cell Lines and Primary Cells to Assess Preservation of Cell Type-specific Functions
Cuiping Pan et al.
MOLECULAR & CELLULAR PROTEOMICS (2009)
In-situ measurement of cellular microenvironments in a microfluidic device
Zhang Lin et al.
LAB ON A CHIP (2009)
A micro cell culture analog (μCCA) with 3-D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs
Jong Hwan Sung et al.
LAB ON A CHIP (2009)
Cell migration into scaffolds under co-culture conditions in a microfluidic platform
Seok Chung et al.
LAB ON A CHIP (2009)
Electrical stimulation systems for cardiac tissue engineering
Nina Tandon et al.
NATURE PROTOCOLS (2009)
Oxygen-mediated enhancement of primary hepatocyte metabolism, functional polarization, gene expression, and drug clearance
Srivatsan Kidambi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Microfabricated tissue gauges to measure and manipulate forces from 3D microtissues
Wesley R. Legant et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Thalidomide induces limb defects by preventing angiogenic outgrowth during early limb formation
Christina Therapontos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
In vitro analysis of a hepatic device with intrinsic microvascular-based channels
Amedeo Carraro et al.
BIOMEDICAL MICRODEVICES (2008)
Effect of cyclic AMP on barrier function of human lymphatic microvascular tubes
Gavrielle M. Price et al.
MICROVASCULAR RESEARCH (2008)
An integrated microfluidic system for long-term perfusion culture and on-line monitoring of intestinal tissue models
Hiroshi Kimura et al.
LAB ON A CHIP (2008)
Cellular imaging predictions of clinical drug-induced liver injury
Jinghai J. Xu et al.
TOXICOLOGICAL SCIENCES (2008)
Development of an osteoblast-based 3D continuous-perfusion microfluidic system for drug screening
Kihoon Jang et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2008)
Reprogramming of human somatic cells to pluripotency with defined factors
In-Hyun Park et al.
NATURE (2008)
Microscale culture of human liver cells for drug development
Salman R. Khetani et al.
NATURE BIOTECHNOLOGY (2008)
Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin
Jacob Hanna et al.
SCIENCE (2007)
Acoustically detectable cellular-level lung injury induced by fluid mechanical stresses in microfluidic airway systems
Dongeun Huh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Microfluidic scaffolds for tissue engineering
Nak Won Choi et al.
NATURE MATERIALS (2007)
An artificial liver sinusoid with a microfluidic endothelial-like barrier for primary hepatocyte culture
Philip J. Lee et al.
BIOTECHNOLOGY AND BIOENGINEERING (2007)
Micromechanical control of cell-cell interactions
Elliot E. Hui et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
Kazutoshi Takahashi et al.
CELL (2006)
Cellular mechanotransduction: putting all the pieces together again
Donald E. Ingber
FASEB JOURNAL (2006)
Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts
WH Zimmermann et al.
NATURE MEDICINE (2006)
A microfluidic culture platform for CNS axonal injury, regeneration and transport
AM Taylor et al.
NATURE METHODS (2005)
Computer-controlled microcirculatory support system for endothelial cell culture and shearing
JW Song et al.
ANALYTICAL CHEMISTRY (2005)
Characterization of protein release from photocrosslinkable hyaluronic acid-polyethylene glycol hydrogel tissue engineering scaffolds
JB Leach et al.
BIOMATERIALS (2005)
Label-free electronic detection of thrombin in blood serum by using an aptamer-based sensor
Y Xiao et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2005)
Development of a microscale cell culture analog to probe naphthalene toxicity
K Viravaidya et al.
BIOTECHNOLOGY PROGRESS (2004)
The design and fabrication of three-chamber microscale cell culture analog devices with integrated dissolved oxygen sensors
A Sin et al.
BIOTECHNOLOGY PROGRESS (2004)
Microscale tissue engineering using gravity-enforced cell assembly
JM Kelm et al.
TRENDS IN BIOTECHNOLOGY (2004)
Engineering biological structures of prescribed shape using self-assembling multicellular systems
K Jakab et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Glucose biosensors based on carbon nanotube nanoelectrode ensembles
YH Lin et al.
NANO LETTERS (2004)
Functional assembly of engineered myocardium by electrical stimulation of cardiac myocytes cultured on scaffolds
M Radisic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Modification of the Cytosensor™ microphysiometer to simultaneously measure extracellular acidification and oxygen consumption rates
SE Eklund et al.
ANALYTICA CHIMICA ACTA (2003)
Method for generation of homogeneous multicellular tumor spheroids applicable to a wide variety of cell types
JM Kelm et al.
BIOTECHNOLOGY AND BIOENGINEERING (2003)
Growth of endothelial cells on microfabricated silicon nitride membranes for an in vitro model of the blood-brain barrier
SG Harris et al.
BIOTECHNOLOGY AND BIOPROCESS ENGINEERING (2003)
In vitro expression of the endothelial phenotype:: Comparative study of primary isolated cells and cell lines, including the novel cell line HPMEC-ST1.6R
RE Unger et al.
MICROVASCULAR RESEARCH (2002)
Microfluidic large-scale integration
T Thorsen et al.
SCIENCE (2002)
Tissue engineering of a differentiated cardiac muscle construct
WH Zimmermann et al.
CIRCULATION RESEARCH (2002)
Determination of blood pO2 using a micromachined Clark-type oxygen electrode
H Suzuki et al.
ANALYTICA CHIMICA ACTA (2001)
Monolithic microfabricated valves and pumps by multilayer soft lithography
MA Unger et al.
SCIENCE (2000)
Trovafloxacin-induced acute hepatitis
MI Lucena et al.
CLINICAL INFECTIOUS DISEASES (2000)
Three-dimensional micro-channel fabrication in polydimethylsiloxane (PDMS) elastomer
BH Jo et al.
JOURNAL OF MICROELECTROMECHANICAL SYSTEMS (2000)