Related references
Note: Only part of the references are listed.Organ-On-A-Chip Platforms: A Convergence of Advanced Materials, Cells, and Microscale Technologies
Samad Ahadian et al.
ADVANCED HEALTHCARE MATERIALS (2018)
Organ-on-a-Chip Systems for Women's Health Applications
Janna Nawroth et al.
ADVANCED HEALTHCARE MATERIALS (2018)
Wet-AMD on a Chip: Modeling Outer Blood-Retinal Barrier In Vitro
Minhwan Chung et al.
ADVANCED HEALTHCARE MATERIALS (2018)
Crosstalk between developing vasculature and optogenetically engineered skeletal muscle improves muscle contraction and angiogenesis
Tatsuya Osaki et al.
BIOMATERIALS (2018)
High-content analysis of three-dimensional tumor spheroids: investigating signaling pathways using small hairpin RNA
Shane R Horman et al.
NATURE METHODS (2018)
3D Bioprinting for Tissue and Organ Fabrication
Yu Shrike Zhang et al.
ANNALS OF BIOMEDICAL ENGINEERING (2017)
Instrumented cardiac microphysiological devices via multimaterial three-dimensional printing
Johan U. Lind et al.
NATURE MATERIALS (2017)
Human Stem Cell-Derived Cardiac Model of Chronic Drug Exposure
Sara S. Nunes et al.
ACS BIOMATERIALS SCIENCE & ENGINEERING (2017)
Contextual Control of Adipose-Derived Stem Cell Function: Implications for Engineered Tumor Models
Katharina Wittmann et al.
ACS BIOMATERIALS SCIENCE & ENGINEERING (2017)
Human Stem Cell-Derived Cardiac Model of Chronic Drug Exposure
Sara S. Nunes et al.
ACS BIOMATERIALS SCIENCE & ENGINEERING (2017)
Contextual Control of Adipose-Derived Stem Cell Function: Implications for Engineered Tumor Models
Katharina Wittmann et al.
ACS BIOMATERIALS SCIENCE & ENGINEERING (2017)
Integrating perfusable vascular networks with a three-dimensional tissue in a microfluidic device
Yuji Nashimoto et al.
INTEGRATIVE BIOLOGY (2017)
A disease model of diabetic nephropathy in a glomerulus-on-a-chip microdevice
Li Wang et al.
LAB ON A CHIP (2017)
A microfluidic trap array for longitudinal monitoring and multi-modal phenotypic analysis of individual stem cell aggregates
E. L. Jackson-Holmes et al.
LAB ON A CHIP (2017)
Integration and application of optical chemical sensors in microbioreactors
Pia Gruber et al.
LAB ON A CHIP (2017)
Organ-on-a-chip devices advance to market
Boyang Zhang et al.
LAB ON A CHIP (2017)
A 3D neurovascular microfluidic model consisting of neurons, astrocytes and cerebral endothelial cells as a blood-brain barrier
Giulia Adriani et al.
LAB ON A CHIP (2017)
A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications
Duc T. T. Phan et al.
LAB ON A CHIP (2017)
WAT-on-a-chip: a physiologically relevant microfluidic system incorporating white adipose tissue
Peter Loskill et al.
LAB ON A CHIP (2017)
3D-templated, fully automated microfluidic input/output multiplexer for endocrine tissue culture and secretion sampling
Xiangpeng Li et al.
LAB ON A CHIP (2017)
Open-top microfluidic device for in vitro three-dimensional capillary beds
Soojung Oh et al.
LAB ON A CHIP (2017)
A portable and reconfigurable multi-organ platform for drug development with onboard microfluidic flow control
J. R. Coppeta et al.
LAB ON A CHIP (2017)
Organs-on-Chips with combined multi-electrode array and transepithelial electrical resistance measurement capabilities
Ben M. Maoz et al.
LAB ON A CHIP (2017)
Organs-on-chips with integrated electrodes for trans-epithelial electrical resistance (TEER) measurements of human epithelial barrier function
Olivier Y. F. Henry et al.
LAB ON A CHIP (2017)
A three-dimensional model of human lung development and disease from pluripotent stem cells
Ya-Wen Chen et al.
NATURE CELL BIOLOGY (2017)
Patient-derived xenografts undergo mouse-specific tumor evolution
Uri Ben-David et al.
NATURE GENETICS (2017)
Human primary liver cancer-derived organoid cultures for disease modeling and drug screening
Laura Broutier et al.
NATURE MEDICINE (2017)
Multisensor-integrated organs-on-chips platform for automated and continual in situ monitoring of organoid behaviors
Yu Shrike Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease
Kelly R. Stevens et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
Membrane-free culture and real-time barrier integrity assessment of perfused intestinal epithelium tubes
Sebastiaan J. Trietsch et al.
NATURE COMMUNICATIONS (2017)
Label-Free and Regenerative Electrochemical Microfluidic Biosensors for Continual Monitoring of Cell Secretomes
Su Ryon Shin et al.
ADVANCED SCIENCE (2017)
Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip
Samira Musah et al.
NATURE BIOMEDICAL ENGINEERING (2017)
Human Gut-On-A-Chip Supports Polarized Infection of Coxsackie B1 Virus In Vitro
Remi Villenave et al.
PLOS ONE (2017)
Microvasculature on a chip: study of the Endothelial Surface Layer and the flow structure of Red Blood Cells
Daria Tsvirkun et al.
SCIENTIFIC REPORTS (2017)
Kinase inhibitor screening using artificial neural networks and engineered cardiac biowires
Genevieve Conant et al.
SCIENTIFIC REPORTS (2017)
InVADE: Integrated Vasculature for Assessing Dynamic Events
Benjamin Fook Lun Lai et al.
ADVANCED FUNCTIONAL MATERIALS (2017)
Recent advances in microfluidic sample preparation and separation techniques for molecular biomarker analysis: A critical review
Mukul Sonker et al.
ANALYTICA CHIMICA ACTA (2017)
The ascendance of microphysiological systems to solve the drug testing dilemma
Eva-Maria Dehne et al.
FUTURE SCIENCE OA (2017)
An end-user perspective on Organ-on-a-Chip: Assays and usability aspects
Abidemi Junaid et al.
CURRENT OPINION IN BIOMEDICAL ENGINEERING (2017)
I-Wire Heart-on-a-Chip II: Biomechanical analysis of contractile, three-dimensional cardiomyocyte tissue constructs
Alison K. Schroer et al.
ACTA BIOMATERIALIA (2017)
I-Wire Heart-on-a -Chip I: Three-dimensional cardiac tissue constructs for physiology and pharmacology
Veniamin Y. Sidorov et al.
ACTA BIOMATERIALIA (2017)
Placenta-on-a-chip: a novel platform to study the biology of the human placenta
Ji Soo Lee et al.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE (2016)
A Novel Three-Dimensional Human Peritubular Microvascular System
Giovanni Ligresti et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2016)
A Quantitative Approach to Screen for Nephrotoxic Compounds In Vitro
Melanie Adler et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2016)
A three-dimensional engineered tumour for spatial snapshot analysis of cell metabolism and phenotype in hypoxic gradients
Darren Rodenhizer et al.
NATURE MATERIALS (2016)
Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro
Kambez H. Benam et al.
NATURE METHODS (2016)
Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip
Hyun Jung Kim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
A Digital-Analog Microfluidic Platform for Patient-Centric Multiplexed Biomarker Diagnostics of Ultralow Volume Samples
Francesco Piraino et al.
ACS NANO (2016)
Human engineered heart tissue as a model system for drug testing
Alexandra Eder et al.
ADVANCED DRUG DELIVERY REVIEWS (2016)
Aptamer-Based Microfluidic Electrochemical Biosensor for Monitoring Cell-Secreted Trace Cardiac Biomarkers
Su Ryon Shin et al.
ANALYTICAL CHEMISTRY (2016)
Dynamic culture yields engineered myocardium with near-adult functional output
Christopher P. Jackman et al.
BIOMATERIALS (2016)
Three-dimensional biomimetic model to reconstitute sprouting lymphangiogenesis in vitro
Sudong Kim et al.
BIOMATERIALS (2016)
Microfluidic assay-based optical measurement techniques for cell analysis: A review of recent progress
Jong-ryul Choi et al.
BIOSENSORS & BIOELECTRONICS (2016)
Nanomaterial based electrochemical sensors for in vitro detection of small molecule metabolites
Fei Xiao et al.
BIOTECHNOLOGY ADVANCES (2016)
Design and Demonstration of a Pumpless 14 Compartment Microphysiological System
Paula G. Miller et al.
BIOTECHNOLOGY AND BIOENGINEERING (2016)
Reverse Engineering Human Pathophysiology with Organs-on-Chips
Donald E. Ingber
CELL (2016)
Human pluripotent stem cell-derived cardiomyocyte based models for cardiotoxicity and drug discovery
Yimu Zhao et al.
EXPERT OPINION ON DRUG SAFETY (2016)
Organoid Models of Human Gastrointestinal Development and Disease
Priya H. Dedhia et al.
GASTROENTEROLOGY (2016)
Three-dimensional models for studying development and disease: moving on from organisms to organs-on-a-chip and organoids
E. L. Jackson et al.
INTEGRATIVE BIOLOGY (2016)
US Emergency Department Visits for Outpatient Adverse Drug Events, 2013-2014
Nadine Shehab et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)
Innovation in the pharmaceutical industry: New estimates of R&D costs
Joseph A. DiMasi et al.
JOURNAL OF HEALTH ECONOMICS (2016)
Metabolic consequences of inflammatory disruption of the blood-brain barrier in an organ-on-chip model of the human neurovascular unit
Jacquelyn A. Brown et al.
JOURNAL OF NEUROINFLAMMATION (2016)
Rapid Mechanically Controlled Rewiring of Neuronal Circuits
Margaret H. Magdesian et al.
JOURNAL OF NEUROSCIENCE (2016)
Development of a microphysiological model of human kidney proximal tubule function
Elijah J. Weber et al.
KIDNEY INTERNATIONAL (2016)
An on-chip microfluidic pressure regulator that facilitates reproducible loading of cells and hydrogels into microphysiological system platforms
Xiaolin Wang et al.
LAB ON A CHIP (2016)
Elastomeric free-form blood vessels for interconnecting organs on chip systems
Weijia Zhang et al.
LAB ON A CHIP (2016)
Interstitial flow regulates the angiogenic response and phenotype of endothelial cells in a 3D culture model
Sudong Kim et al.
LAB ON A CHIP (2016)
Modular, pumpless body-on-a-chip platform for the co-culture of GI tract epithelium and 3D primary liver tissue
Mandy B. Esch et al.
LAB ON A CHIP (2016)
A microphysiological model of the human placental barrier
Cassidy Blundell et al.
LAB ON A CHIP (2016)
Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels
Xiaolin Wang et al.
LAB ON A CHIP (2016)
Bioprinted thrombosis-on-a-chip
Yu Shrike Zhang et al.
LAB ON A CHIP (2016)
3D printed microfluidic devices: enablers and barriers
Sidra Waheed et al.
LAB ON A CHIP (2016)
Biowire platform for maturation of human pluripotent stem cell-derived cardiomyocytes
Xuetao Sun et al.
METHODS (2016)
A 3D bioprinting system to produce human-scale tissue constructs with structural integrity
Hyun-Wook Kang et al.
NATURE BIOTECHNOLOGY (2016)
Biodegradable scaffold with built-in vasculature for organ-on-a-chip engineering and direct surgical anastomosis
Boyang Zhang et al.
NATURE MATERIALS (2016)
Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation
Laura Broutier et al.
NATURE PROTOCOLS (2016)
Three-dimensional bioprinting of thick vascularized tissues
David B. Kolesky et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Spontaneous Formation of Extensive Vessel-Like Structures in Murine Engineered Heart Tissue
Andrea Stoehr et al.
TISSUE ENGINEERING PART A (2016)
Modeling Compound-Induced Fibrogenesis In Vitro Using Three-Dimensional Bioprinted Human Liver Tissues
Leah M. Norona et al.
TOXICOLOGICAL SCIENCES (2016)
A High-Throughput Microfluidic Platform for Mammalian Cell Transfection and Culturing
Kristina Woodruff et al.
SCIENTIFIC REPORTS (2016)
Three-dimensional microtissues essentially contribute to preclinical validations of therapeutic targets in breast cancer
Natalie Falkenberg et al.
CANCER MEDICINE (2016)
Retinal Organoids from Pluripotent Stem Cells Efficiently Recapitulate Retinogenesis
Manuela Voelkner et al.
STEM CELL REPORTS (2016)
Human Engineered Heart Tissue: Analysis of Contractile Force
Ingra Mannhardt et al.
STEM CELL REPORTS (2016)
Highly Elastic and Moldable Polyester Biomaterial for Cardiac Tissue Engineering Applications
Locke Davenport Huyer et al.
ACS BIOMATERIALS SCIENCE & ENGINEERING (2016)
Personalized Disease Models on a Chip
Nalin Tejavibulya et al.
CELL SYSTEMS (2016)
Highly Elastic and Moldable Polyester Biomaterial for Cardiac Tissue Engineering Applications
Locke Davenport Huyer et al.
ACS BIOMATERIALS SCIENCE & ENGINEERING (2016)
Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs
Carlota Oleaga et al.
SCIENTIFIC REPORTS (2016)
3D microtumors in vitro supported by perfused vascular networks
Agua Sobrino et al.
SCIENTIFIC REPORTS (2016)
Bioprinting of 3D Convoluted Renal Proximal Tubules on Perfusable Chips
Kimberly A. Homan et al.
SCIENTIFIC REPORTS (2016)
High-throughput compound evaluation on 3D networks of neurons and glia in a microfluidic platform
Nienke R. Wevers et al.
SCIENTIFIC REPORTS (2016)
Pharmacokinetic profile that reduces nephrotoxicity of gentamicin in a perfused kidney-on-a-chip
Sejoong Kim et al.
BIOFABRICATION (2016)
Application of a Micropatterned Cocultured Hepatocyte System To Predict Preclinical and Human-Specific Drug Metabolism
T. Eric Ballard et al.
DRUG METABOLISM AND DISPOSITION (2016)
Photoreactive interpenetrating network of hyaluronic acid and Puramatrix as a selectively tunable scaffold for neurite growth
Parastoo Khoshakhlagh et al.
ACTA BIOMATERIALIA (2015)
Microfluidic Multiculture Assay to Analyze Biomolecular Signaling in Angiogenesis
Ashleigh B. Theberge et al.
ANALYTICAL CHEMISTRY (2015)
Thalidomide-induced teratogenesis: History and mechanisms
Neil Vargesson
BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS (2015)
A 3D-microtissue-based phenotypic screening of radiation resistant tumor cells with synchronized chemotherapeutic treatment
Natasa Anastasov et al.
BMC CANCER (2015)
An analysis of FDA-approved drugs for inflammation and autoimmune diseases
Michael S. Kinch et al.
DRUG DISCOVERY TODAY (2015)
Biology coming full circle: Joining the whole and the parts
John P. Wikswo et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2015)
3D spherical microtissues and microfluidic technology for multi-tissue experiments and analysis
Jin-Young Kim et al.
JOURNAL OF BIOTECHNOLOGY (2015)
Differentiation of neuroepithelial stem cells into functional dopaminergic neurons in 3D microfluidic cell culture
Edinson Lucumi Moreno et al.
LAB ON A CHIP (2015)
Microengineered peripheral nerve-on-a-chip for preclinical physiological testing
Renee M. Huval et al.
LAB ON A CHIP (2015)
Measuring direct current trans-epithelial electrical resistance in organ-on-a-chip microsystems
Mathieu Odijk et al.
LAB ON A CHIP (2015)
Adding the 'heart' to hanging drop networks for microphysiological multi-tissue experiments
Saeed Rismani Yazdi et al.
LAB ON A CHIP (2015)
A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents
Ilka Maschmeyer et al.
LAB ON A CHIP (2015)
Artery-on-a-chip platform for automated, multimodal assessment of cerebral blood vessel structure and function
Sanjesh Yasotharan et al.
LAB ON A CHIP (2015)
A lung-on-a-chip array with an integrated bio-inspired respiration mechanism
Andreas O. Stucki et al.
LAB ON A CHIP (2015)
A microengineered pathophysiological model of early-stage breast cancer
Yoonseok Choi et al.
LAB ON A CHIP (2015)
Microfluidic vascularized bone tissue model with hydroxyapatite-incorporated extracellular matrix
Norhana Jusoh et al.
LAB ON A CHIP (2015)
Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis
Minoru Takasato et al.
NATURE (2015)
Nature Biotechnology's academic spinouts of 2014
Aaron Bouchie et al.
NATURE BIOTECHNOLOGY (2015)
Hormone and Drug-Mediated Modulation of Glucose Metabolism in a Microscale Model of the Human Liver
Matthew D. Davidson et al.
TISSUE ENGINEERING PART C-METHODS (2015)
Prediction of Drug-Induced Liver Injury in Micropatterned Co-cultures Containing iPSC-Derived Human Hepatocytes
Brenton R. Ware et al.
TOXICOLOGICAL SCIENCES (2015)
μOrgano: A Lego®-Like Plug & Play System for Modular Multi-Organ-Chips
Peter Loskill et al.
PLOS ONE (2015)
A Novel Dynamic Neonatal Blood-Brain Barrier on a Chip
Sudhir P. Deosarkar et al.
PLOS ONE (2015)
Human 3D vascularized organotypic microfluidic assays to study breast cancer cell extravasation
Jessie S. Jeon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Human iPSC-based Cardiac Microphysiological System For Drug Screening Applications
Anurag Mathur et al.
SCIENTIFIC REPORTS (2015)
Quantitative Systems Pharmacology Approaches Applied to Microphysiological Systems (MPS): Data Interpretation and Multi-MPS Integration
J. Yu et al.
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2015)
Establishment of a Hepatocyte-Kupffer Cell Coculture Model for Assessment of Proinflammatory Cytokine Effects on Metabolizing Enzymes and Drug Transporters
Theresa V. Nguyen et al.
DRUG METABOLISM AND DISPOSITION (2015)
3D Bioprinting of Vascularized, Heterogeneous Cell-Laden Tissue Constructs
David B. Kolesky et al.
ADVANCED MATERIALS (2014)
Rechanneling the cardiac proarrhythmia safety paradigm: A meeting report from the Cardiac Safety Research Consortium
Philip T. Sager et al.
AMERICAN HEART JOURNAL (2014)
Robust T-tubulation and maturation of cardiomyocytes using tissue engineered epicardial mimetics
Weining Bian et al.
BIOMATERIALS (2014)
Design, development, and validation of an in-situ biosensor array for metabolite monitoring of cell cultures
Cristina Boero et al.
BIOSENSORS & BIOELECTRONICS (2014)
Development and Applications of CRISPR-Cas9 for Genome Engineering
Patrick D. Hsu et al.
CELL (2014)
Engineering Adolescence Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes
Xiulan Yang et al.
CIRCULATION RESEARCH (2014)
The Clinical Liver Safety Assessment Best Practices Workshop: Rationale, Goals, Accomplishments and the Future
Paul B. Watkins et al.
DRUG SAFETY (2014)
Pumps for microfluidic cell culture
Chang Kyu Byun et al.
ELECTROPHORESIS (2014)
Tissue-engineered microenvironment systems for modeling human vasculature
Anna Tourovskaia et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2014)
An in vitro osteosarcoma 3D microtissue model for drug development
Markus Rimann et al.
JOURNAL OF BIOTECHNOLOGY (2014)
Body-on-a-chip simulation with gastrointestinal tract and liver tissues suggests that ingested nanoparticles have the potential to cause liver injury
Mandy B. Esch et al.
LAB ON A CHIP (2014)
3D bioprinting of tissues and organs
Sean V. Murphy et al.
NATURE BIOTECHNOLOGY (2014)
Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies
Gang Wang et al.
NATURE MEDICINE (2014)
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
Amir Shlomai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Mechanotransduction of fluid stresses governs 3D cell migration
William J. Polacheck et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Organogenesis in a dish: Modeling development and disease using organoid technologies
Madeline A. Lancaster et al.
SCIENCE (2014)
Predictivity of dog co-culture model, primary human hepatocytes and HepG2 cells for the detection of hepatotoxic drugs in humans
Franck A. Atienzar et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2014)
Bioreactor for modulation of cardiac microtissue phenotype by combined static stretch and electrical stimulation
Jason W. Miklas et al.
BIOFABRICATION (2014)
Controlling the structural and functional anisotropy of engineered cardiac tissues
Weining Bian et al.
BIOFABRICATION (2014)
Reconfigurable microfluidic hanging drop network for multi-tissue interaction and analysis
Olivier Frey et al.
NATURE COMMUNICATIONS (2014)
Integrated circuit-based electrochemical sensor for spatially resolved detection of redox-active metabolites in biofilms
Daniel L. Bellin et al.
NATURE COMMUNICATIONS (2014)
Simple, Low-Cost Styrene-Ethylene/Butylene-Styrene Microdevices for Electrokinetic Applications
Mark D. Borysiak et al.
ANALYTICAL CHEMISTRY (2013)
A standalone perfusion platform for drug testing and target validation in micro-vessel networks
Boyang Zhang et al.
BIOMICROFLUIDICS (2013)
Cellular response to micropatterned growth promoting and inhibitory substrates
Wiam Belkaid et al.
BMC BIOTECHNOLOGY (2013)
On being the right size: scaling effects in designing a human-on-a-chip
Christopher Moraes et al.
INTEGRATIVE BIOLOGY (2013)
Screening therapeutic EMT blocking agents in a three-dimensional microenvironment
Amir R. Aref et al.
INTEGRATIVE BIOLOGY (2013)
Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment
Kyung-Jin Jang et al.
INTEGRATIVE BIOLOGY (2013)
Adhesive interaction of functionalized particles and endothelium in idealized microvascular networks
Giuseppina Lamberti et al.
MICROVASCULAR RESEARCH (2013)
SyM-BBB: a microfluidic blood brain barrier model
Balabhaskar Prabhakarpandian et al.
LAB ON A CHIP (2013)
Spatially monitoring oxygen level in 3D microfabricated cell culture systems using optical oxygen sensing beads
Lin Wang et al.
LAB ON A CHIP (2013)
Scaling and systems biology for integrating multiple organs-on-a-chip
John P. Wikswo et al.
LAB ON A CHIP (2013)
A microfluidic platform for generating large-scale nearly identical human microphysiological vascularized tissue arrays
Yu-Hsiang Hsu et al.
LAB ON A CHIP (2013)
Clear castable polyurethane elastomer for fabrication of microfluidic devices
Karel Domansky et al.
LAB ON A CHIP (2013)
Microfluidic titer plate for stratified 3D cell culture
Sebastiaan J. Trietsch et al.
LAB ON A CHIP (2013)
A dynamic multi-organ-chip for long-term cultivation and substance testing proven by 3D human liver and skin tissue co-culture
Ilka Wagner et al.
LAB ON A CHIP (2013)
Workshop meeting report Organs-on-Chips: human disease models
Anja van de Stolpe et al.
LAB ON A CHIP (2013)
Simple replica micromolding of biocompatible styrenic elastomers
Mark D. Borysiak et al.
LAB ON A CHIP (2013)
Engineering of functional, perfusable 3D microvascular networks on a chip
Sudong Kim et al.
LAB ON A CHIP (2013)
Cerebral organoids model human brain development and microcephaly
Madeline A. Lancaster et al.
NATURE (2013)
Biowire: a platform for maturation of human pluripotent stem cell-derived cardiomyocytes
Sara S. Nunes et al.
NATURE METHODS (2013)
Microfabrication of human organs-on-chips
Dongeun Huh et al.
NATURE PROTOCOLS (2013)
Microfluidic trap array for massively parallel imaging of Drosophila embryos
Thomas J. Levario et al.
NATURE PROTOCOLS (2013)
Design and formulation of functional pluripotent stem cell-derived cardiac microtissues
Nimalan Thavandiran et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong et al.
SCIENCE (2013)
In Vitro Perfused Human Capillary Networks
Monica L. Moya et al.
TISSUE ENGINEERING PART C-METHODS (2013)
Use of Micropatterned Cocultures to Detect Compounds That Cause Drug-Induced Liver Injury in Humans
Salman R. Khetani et al.
TOXICOLOGICAL SCIENCES (2013)
HeLiVa platform: integrated heart-liver-vascular systems for drug testing in human health and disease
Gordana Vunjak-Novakovic et al.
STEM CELL RESEARCH & THERAPY (2013)
Meeting the Challenge of Predicting Hepatic Clearance of Compounds Slowly Metabolized by Cytochrome P450 Using a Novel Hepatocyte Model, HepatoPac
Tom S. Chan et al.
DRUG METABOLISM AND DISPOSITION (2013)
Substrate Micropatterning as a New in Vitro Cell Culture System to Study Myelination
Dalinda Liazoghli et al.
ACS CHEMICAL NEUROSCIENCE (2012)
Drug-Induced Nephrotoxicity and Its Biomarkers
Sun Young Kim et al.
BIOMOLECULES & THERAPEUTICS (2012)
Atomic Force Microscopy Reveals Important Differences in Axonal Resistance to Injury
Margaret H. Magdesian et al.
BIOPHYSICAL JOURNAL (2012)
Mechanism of a flow-gated angiogenesis switch: early signaling events at cell-matrix and cell-cell junctions
Vernella Vickerman et al.
INTEGRATIVE BIOLOGY (2012)
In vitro formation and characterization of a perfusable three-dimensional tubular capillary network in microfluidic devices
Ju Hun Yeon et al.
LAB ON A CHIP (2012)
Engineers are from PDMS-land, Biologists are from Polystyrenia
Erwin Berthier et al.
LAB ON A CHIP (2012)
Characterization of a microfluidic in vitro model of the blood-brain barrier (μBBB)
Ross Booth et al.
LAB ON A CHIP (2012)
Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow
Hyun Jung Kim et al.
LAB ON A CHIP (2012)
Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues
Jordan S. Miller et al.
NATURE MATERIALS (2012)
Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels
Yoojin Shin et al.
NATURE PROTOCOLS (2012)
In vitro microvessels for the study of angiogenesis and thrombosis
Ying Zheng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function
Ioannis K. Zervantonakis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
A Human Disease Model of Drug Toxicity-Induced Pulmonary Edema in a Lung-on-a-Chip Microdevice
Dongeun Huh et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Toward engineering functional organ modules by additive manufacturing
Francoise Marga et al.
BIOFABRICATION (2012)
Rapid isothermal substrate microfabrication of a biocompatible thermoplastic elastomer for cellular contact guidance
Maxime D. Guillemette et al.
ACTA BIOMATERIALIA (2011)
Neuromuscular junction formation between human stem cell-derived motoneurons and human skeletal muscle in a defined system
Xiufang Guo et al.
BIOMATERIALS (2011)
Epithelium damage and protection during reopening of occluded airways in a physiologic microfluidic pulmonary airway model
Hossein Tavana et al.
BIOMEDICAL MICRODEVICES (2011)
A microfluidic membrane device to mimic critical components of the vascular microenvironment
Suthan Srigunapalan et al.
BIOMICROFLUIDICS (2011)
Stage-Specific Optimization of Activin/Nodal and BMP Signaling Promotes Cardiac Differentiation of Mouse and Human Pluripotent Stem Cell Lines
Steven J. Kattman et al.
CELL STEM CELL (2011)
Patterning cells and shear flow conditions: Convenient observation of endothelial cell remoulding, enhanced production of angiogenesis factors and drug response
Li Wang et al.
LAB ON A CHIP (2011)
Axon diodes for the reconstruction of oriented neuronal networks in microfluidic chambers
Jean-Michel Peyrin et al.
LAB ON A CHIP (2011)
A software-programmable microfluidic device for automated biology
Luis M. Fidalgo et al.
LAB ON A CHIP (2011)
Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome
Masayuki Yazawa et al.
NATURE (2011)
A microfluidic array for large-scale ordering and orientation of embryos
Kwanghun Chung et al.
NATURE METHODS (2011)
Human Engineered Heart Tissue as a Versatile Tool in Basic Research and Preclinical Toxicology
Sebastian Schaaf et al.
PLOS ONE (2011)
From 3D cell culture to organs-on-chips
Dongeun Huh et al.
TRENDS IN CELL BIOLOGY (2011)
Convenient Method for Modifying Poly(dimethylsiloxane) To Be Airtight and Resistive against Absorption of Small Molecules
Kangning Ren et al.
ANALYTICAL CHEMISTRY (2010)
A microfluidic hepatic coculture platform for cell-based drug metabolism studies
Eric Novik et al.
BIOCHEMICAL PHARMACOLOGY (2010)
SPENDING ON NEW DRUG DEVELOPMENT
Christopher Paul Adams et al.
HEALTH ECONOMICS (2010)
A microfluidic platform for probing small artery structure and function
Axel Guenther et al.
LAB ON A CHIP (2010)
A multi-layer microfluidic device for efficient culture and analysis of renal tubular cells
Kyung-Jin Jang et al.
LAB ON A CHIP (2010)
Dynamics of Liquid Plugs of Buffer and Surfactant Solutions in a Micro-Engineered.Pulmonary Airway Model
Hossein Tavana et al.
LANGMUIR (2010)
Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
Xonia Carvajal-Vergara et al.
NATURE (2010)
How to improve R&D productivity: the pharmaceutical industry's grand challenge
Steven M. Paul et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Achieving pluripotency
Kim Baumann
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome.
Alessandra Moretti et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Correction: Mapping Proprioception across a 2D Horizontal Workspace
Elizabeth T. Wilson et al.
PLoS One (2010)
Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures
Alexander Ploss et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Reconstituting Organ-Level Lung Functions on a Chip
Dongeun Huh et al.
SCIENCE (2010)
Parylene-coating in PDMS microfluidic channels prevents the absorption of fluorescent dyes
Hirotaka Sasaki et al.
SENSORS AND ACTUATORS B-CHEMICAL (2010)
Synthesis and characterization of a biodegradable elastomer featuring a dual crosslinking mechanism
Richard T. Tran et al.
SOFT MATTER (2010)
Tissue engineering by self-assembly and bio-printing of living cells
Karoly Jakab et al.
BIOFABRICATION (2010)
Evaluation of a microfluidic based cell culture platform with primary human hepatocytes for the prediction of hepatic clearance in human
P. Chao et al.
BIOCHEMICAL PHARMACOLOGY (2009)
Microfeature guided skeletal muscle tissue engineering for highly organized 3-dimensional free-standing constructs
Mai T. Lam et al.
BIOMATERIALS (2009)
Scaffold-free vascular tissue engineering using bioprinting
Cyrille Norotte et al.
BIOMATERIALS (2009)
Development of high throughput optical sensor array for on-line pH monitoring in micro-scale cell culture environment
Min-Hsien Wu et al.
BIOMEDICAL MICRODEVICES (2009)
A Novel System for Evaluation of Drug Mixtures for Potential Efficacy in Treating Multidrug Resistant Cancers
Daniel A. Tatosian et al.
BIOTECHNOLOGY AND BIOENGINEERING (2009)
Characterization of a Gastrointestinal Tract Microscale Cell Culture Analog Used to Predict Drug Toxicity
Gretchen J. Mahler et al.
BIOTECHNOLOGY AND BIOENGINEERING (2009)
Pluripotent Stem Cells and Disease Modeling
Alan Colman et al.
CELL STEM CELL (2009)
Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease
Krishanu Saha et al.
CELL STEM CELL (2009)
Comparative Proteomic Phenotyping of Cell Lines and Primary Cells to Assess Preservation of Cell Type-specific Functions
Cuiping Pan et al.
MOLECULAR & CELLULAR PROTEOMICS (2009)
In-situ measurement of cellular microenvironments in a microfluidic device
Zhang Lin et al.
LAB ON A CHIP (2009)
A micro cell culture analog (μCCA) with 3-D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs
Jong Hwan Sung et al.
LAB ON A CHIP (2009)
Cell migration into scaffolds under co-culture conditions in a microfluidic platform
Seok Chung et al.
LAB ON A CHIP (2009)
Electrical stimulation systems for cardiac tissue engineering
Nina Tandon et al.
NATURE PROTOCOLS (2009)
Oxygen-mediated enhancement of primary hepatocyte metabolism, functional polarization, gene expression, and drug clearance
Srivatsan Kidambi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Microfabricated tissue gauges to measure and manipulate forces from 3D microtissues
Wesley R. Legant et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Thalidomide induces limb defects by preventing angiogenic outgrowth during early limb formation
Christina Therapontos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
In vitro analysis of a hepatic device with intrinsic microvascular-based channels
Amedeo Carraro et al.
BIOMEDICAL MICRODEVICES (2008)
Effect of cyclic AMP on barrier function of human lymphatic microvascular tubes
Gavrielle M. Price et al.
MICROVASCULAR RESEARCH (2008)
An integrated microfluidic system for long-term perfusion culture and on-line monitoring of intestinal tissue models
Hiroshi Kimura et al.
LAB ON A CHIP (2008)
Cellular imaging predictions of clinical drug-induced liver injury
Jinghai J. Xu et al.
TOXICOLOGICAL SCIENCES (2008)
Development of an osteoblast-based 3D continuous-perfusion microfluidic system for drug screening
Kihoon Jang et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2008)
Reprogramming of human somatic cells to pluripotency with defined factors
In-Hyun Park et al.
NATURE (2008)
Microscale culture of human liver cells for drug development
Salman R. Khetani et al.
NATURE BIOTECHNOLOGY (2008)
Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin
Jacob Hanna et al.
SCIENCE (2007)
Acoustically detectable cellular-level lung injury induced by fluid mechanical stresses in microfluidic airway systems
Dongeun Huh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Microfluidic scaffolds for tissue engineering
Nak Won Choi et al.
NATURE MATERIALS (2007)
An artificial liver sinusoid with a microfluidic endothelial-like barrier for primary hepatocyte culture
Philip J. Lee et al.
BIOTECHNOLOGY AND BIOENGINEERING (2007)
Micromechanical control of cell-cell interactions
Elliot E. Hui et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
Kazutoshi Takahashi et al.
CELL (2006)
Cellular mechanotransduction: putting all the pieces together again
Donald E. Ingber
FASEB JOURNAL (2006)
Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts
WH Zimmermann et al.
NATURE MEDICINE (2006)
A microfluidic culture platform for CNS axonal injury, regeneration and transport
AM Taylor et al.
NATURE METHODS (2005)
Computer-controlled microcirculatory support system for endothelial cell culture and shearing
JW Song et al.
ANALYTICAL CHEMISTRY (2005)
Characterization of protein release from photocrosslinkable hyaluronic acid-polyethylene glycol hydrogel tissue engineering scaffolds
JB Leach et al.
BIOMATERIALS (2005)
Label-free electronic detection of thrombin in blood serum by using an aptamer-based sensor
Y Xiao et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2005)
Development of a microscale cell culture analog to probe naphthalene toxicity
K Viravaidya et al.
BIOTECHNOLOGY PROGRESS (2004)
The design and fabrication of three-chamber microscale cell culture analog devices with integrated dissolved oxygen sensors
A Sin et al.
BIOTECHNOLOGY PROGRESS (2004)
Microscale tissue engineering using gravity-enforced cell assembly
JM Kelm et al.
TRENDS IN BIOTECHNOLOGY (2004)
Engineering biological structures of prescribed shape using self-assembling multicellular systems
K Jakab et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Glucose biosensors based on carbon nanotube nanoelectrode ensembles
YH Lin et al.
NANO LETTERS (2004)
Functional assembly of engineered myocardium by electrical stimulation of cardiac myocytes cultured on scaffolds
M Radisic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Modification of the Cytosensor™ microphysiometer to simultaneously measure extracellular acidification and oxygen consumption rates
SE Eklund et al.
ANALYTICA CHIMICA ACTA (2003)
Method for generation of homogeneous multicellular tumor spheroids applicable to a wide variety of cell types
JM Kelm et al.
BIOTECHNOLOGY AND BIOENGINEERING (2003)
Growth of endothelial cells on microfabricated silicon nitride membranes for an in vitro model of the blood-brain barrier
SG Harris et al.
BIOTECHNOLOGY AND BIOPROCESS ENGINEERING (2003)
In vitro expression of the endothelial phenotype:: Comparative study of primary isolated cells and cell lines, including the novel cell line HPMEC-ST1.6R
RE Unger et al.
MICROVASCULAR RESEARCH (2002)
Microfluidic large-scale integration
T Thorsen et al.
SCIENCE (2002)
Tissue engineering of a differentiated cardiac muscle construct
WH Zimmermann et al.
CIRCULATION RESEARCH (2002)
Determination of blood pO2 using a micromachined Clark-type oxygen electrode
H Suzuki et al.
ANALYTICA CHIMICA ACTA (2001)
Monolithic microfabricated valves and pumps by multilayer soft lithography
MA Unger et al.
SCIENCE (2000)
Trovafloxacin-induced acute hepatitis
MI Lucena et al.
CLINICAL INFECTIOUS DISEASES (2000)
Three-dimensional micro-channel fabrication in polydimethylsiloxane (PDMS) elastomer
BH Jo et al.
JOURNAL OF MICROELECTROMECHANICAL SYSTEMS (2000)
Share Paper
