Journal
MICROSCOPY
Volume 62, Issue 2, Pages 317-320Publisher
OXFORD UNIV PRESS
DOI: 10.1093/jmicro/dfs069
Keywords
serial block-face SEM; back-scattered image; 3-D; double-axis EM tomography; cell fusion; rheumatoid arthritis
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Funding
- Ministry of Education, Culture, Sports, Science and Technology of Japan [24650181]
- Ministry of Health and Labor of Japan
- Grants-in-Aid for Scientific Research [24590423, 24650181] Funding Source: KAKEN
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To evaluate the advantages of combination of two advanced electron microscopic technologies such as serial block-face scanning electron microscopy and double-axis electron beam tomography, we analyzed the three-dimensional morphology of cellular relationships between dendritic and plasma cells in the synovial membrane from patients with rheumatoid arthritis, using the combined approach.
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