Journal
FRONTIERS IN ENDOCRINOLOGY
Volume 6, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fendo.2015.00024
Keywords
ethnic groups; bone; muscle; pQCT; DXA; fracture; skeletal; bone mineral density
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Funding
- Medical Research Council (MRC) [0105960371, 0123261351]
- Department for International Development (DFID)
- Medical Research Council [MC_U105960371, MC_U123292701, MC_U123292700] Funding Source: researchfish
- MRC [MC_U123292700, MC_U105960371, MC_U123292701] Funding Source: UKRI
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There are differences in bone health between ethnic groups in both men and in women. Variations in body size and composition are likely to contribute to reported differences. Most studies report ethnic differences in areal bone mineral density (aBMD), which do not consistently parallel ethnic patterns in fracture rates. This suggests that other parameters beside aBMD should be considered when determining fracture risk between and within populations, including other aspects of bone strength: bone structure and microarchitecture, as well as muscle strength (mass, force generation, anatomy) and fat mass. We review what is known about differences in bone-densitometry-derived outcomes between ethnic groups and the extent to which they account for the differences in fracture risk. Studies are included that were published primarily between 1994 and 2014. A one size fits all approach should definitely not be used to understand better ethnic differences in fracture risk.
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