Journal
CENTRAL EUROPEAN JOURNAL OF MEDICINE
Volume 4, Issue 2, Pages 141-155Publisher
VERSITA
DOI: 10.2478/s11536-008-0088-9
Keywords
Antimicrobial agents; Resistance development; Efflux; Alteration of drug target; Antibacterials
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Funding
- Research foundation Flanders (FWO- Vlaanderen)
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The development of antimicrobial resistance by bacteria is inevitable and is considered as a major problem in the treatment of bacterial infections in the hospital and in the community. Despite efforts to develop new therapeutics that interact with new targets, resistance has been reported even to these agents. In this review, an overview is given of the many therapeutic possibilities that exist for treatment of bacterial infections and how bacteria become resistant to these therapeutics.
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