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Diabetes in Asia Epidemiology, Risk Factors, and Pathophysiology
Juliana C. N. Chan et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2009)
10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study
G. A. Bray et al.
LANCET (2009)
Voglibose for prevention of type 2 diabetes mellitus: a randomised, double-blind trial in Japanese individuals with impaired glucose tolerance
Ryuzo Kawamori et al.
LANCET (2009)
Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion
Valeriya Lyssenko et al.
NATURE GENETICS (2009)
Human P-selectin glycoprotein ligand-1 is a functional receptor for enterovirus 71
Yorihiro Nishimura et al.
NATURE MEDICINE (2009)
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
Markus Feuerer et al.
NATURE MEDICINE (2009)
Sex Hormone-Binding Globulin and Risk of Type 2 Diabetes in Women and Men.
Eric L. Ding et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Three-Year Efficacy of Complex Insulin Regimens in Type 2 Diabetes
Rury R. Holman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Growth factor control of pancreatic islet regeneration and function
Anke Assmann et al.
PEDIATRIC DIABETES (2009)
Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 Diabetes
Varman T. Samuel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
miR-375 maintains normal pancreatic α- and β-cell mass
Matthew N. Poy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Mechanism of action of exenatide to reduce postprandial hyperglycemia in type 2 diabetes
Antonio Cervera et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)
Exenatide effects on diabetes, obesity, cardiovascular risk factors and hepatic biomarkers in patients with type 2 diabetes treated for at least 3 years
David C. Klonoff et al.
CURRENT MEDICAL RESEARCH AND OPINION (2008)
Response to Comment on: Kloting et al. (2008) Autocrine IGF-1 Action in Adipocytes Controls Systemic IGF-1 Concentrations and Growth: Diabetes 57:2074-2082
J. C. Bruning et al.
DIABETES (2008)
Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals
Guenther Boden et al.
DIABETES (2008)
Pancreatic β-cell mass in European subjects with type 2 diabetes
J. Rahier et al.
DIABETES OBESITY & METABOLISM (2008)
The role for endoplasmic reticulum stress in diabetes mellitus
Decio L. Eizirik et al.
ENDOCRINE REVIEWS (2008)
Intracellular Lipid Accumulation in Liver and Muscle and the Insulin Resistance Syndrome
Cristina Lara-Castro et al.
ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA (2008)
The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention Study: a 20-year follow-up study
Guangwei Li et al.
LANCET (2008)
Effect of intensive insulin therapy on β-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes:: a multicentre randomised parallel-group trial
Jianping Weng et al.
LANCET (2008)
Loss of the Tuberous Sclerosis Complex Tumor Suppressors Triggers the Unfolded Protein Response to Regulate Insulin Signaling and Apoptosis
Umut Ozcan et al.
MOLECULAR CELL (2008)
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
Adilson Guilherme et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Clinical Risk Factors, DNA Variants, and the Development of Type 2 Diabetes.
Valeriya Lyssenko et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Effects of intensive glucose lowering in type 2 diabetes
Hertzel C. Gerstein et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
10-year follow-up of intensive glucose control in type 2 diabetes
Rury R. Holman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Dissection of the insulin signaling pathway via quantitative phosphoproteomics
Marcus Krueger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Loss of 50% of excess weight using a very low energy diet improves insulin-stimulated glucose disposal and skeletal muscle insulin signalling in obese insulin-treated type 2 diabetic patients
I. M. Jazet et al.
DIABETOLOGIA (2008)
SOCS proteins causing trouble in insulin action
P. Lebrun et al.
ACTA PHYSIOLOGICA (2008)
The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients
P. Marchetti et al.
DIABETOLOGIA (2007)
Annual incidence and relative risk of diabetes in people with various categories of dysglycemia: A systematic overview and meta-analysis of prospective studies
Hertzel C. Gerstein et al.
DIABETES RESEARCH AND CLINICAL PRACTICE (2007)
Protein kinase C-ζ activation markedly enhances β-cell proliferation -: An essential role in growth factor-mediated β-cell mitogenesis
Rupang C. Vasavada et al.
DIABETES (2007)
Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance
Cheol Soo Choi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes
Valeriya Lyssenko et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Meta-analysis: The effect of dietary counseling for weight loss
Michael L. Dansinger et al.
ANNALS OF INTERNAL MEDICINE (2007)
Signal integration in the endoplasmic reticulum unfolded protein response
David Ron et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Diabetes epidemiology: Guiding clinical and public health practice - The Kelly West Award Lecture, 2006
William H. Herman
DIABETES CARE (2007)
被撤回的出版物: Common inhibitory serine sites phosphorylated by IRS-1 kinases, triggered by insulin and inducers of insulin resistance (Retracted article. See vol. 293, pg. 7266, 2018)
Avia Herschkovitz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
Richa Saxena et al.
SCIENCE (2007)
Mitochondrial respiration is decreased in skeletal muscle of patients with type 2 diabetes
Martin Mogensen et al.
DIABETES (2007)
Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance
Li Liu et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single-dose administration in type 2 diabetic patients
Bogdan Balas et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)
Impaired fasting glucose and impaired glucose tolerance - Implications for care
David M. Nathan et al.
DIABETES CARE (2007)
Inhibition of protein kinase Cε prevents hepatic insulin resistance in nonalcoholic fatty liver disease
Varman T. Samuel et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Thiazolidinediones improve β-cell function in type 2 diabetic patients
Amalia Gastaldelli et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)
A genome-wide association study identifies novel risk loci for type 2 diabetes
Robert Sladek et al.
NATURE (2007)
Human islet amyloid polypeptide oligomers disrupt cell coupling, induce apoptosis, and impair insulin secretion in isolated human islets
Robert A. Ritzel et al.
DIABETES (2007)
Effects of pyridoxamine in combined phase 2 studies of patients with type 1 and type 2 diabetes and overt nephropathy
Mark E. Williams et al.
AMERICAN JOURNAL OF NEPHROLOGY (2007)
The DREAM trial - Reply
Hertzel C. Gerstein et al.
LANCET (2006)
Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy
Steven E. Kahn et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Sustained reduction in the incidence of type 2 diabetes by lifestyle intervention:: follow-up of the Finnish Diabetes Prevention Study
Jaana Lindstrom et al.
LANCET (2006)
TLR4 links innate immunity and fatty acid-induced insulin resistance
Hang Shi et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Attenuation of leptin and insulin signaling by SOCS proteins
Jane K. Howard et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2006)
Contributions of β-cell dysfunction and insulin resistance to the pathogenesis of impaired glucose tolerance and impaired fasting glucose
MA Abdul-Ghani et al.
DIABETES CARE (2006)
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
SFA Grant et al.
NATURE GENETICS (2006)
IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas transplant recipients
K Bouzakri et al.
DIABETES (2006)
The unique cytoarchitecture of human pancreatic islets has implications for islet cell function
O Cabrera et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Effect of pioglitazone on pancreatic β-cell function and diabetes risk in Hispanic women with prior gestational diabetes
AH Xiang et al.
DIABETES (2006)
The Indian Diabetes Prevention Programme shows that lifestyle modification and metformin prevent type 2 diabetes in Asian Indian subjects with impaired glucose tolerance (IDPP-1)
A Ramachandran et al.
DIABETOLOGIA (2006)
Dose-response relation between sulfonylurea drugs and mortality in type 2 diabetes mellitus: a population-based cohort study
SH Simpson et al.
CANADIAN MEDICAL ASSOCIATION JOURNAL (2006)
Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents
K Morino et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events):: a randomised controlled trial
JA Dormandy et al.
LANCET (2005)
Roles of mTOR and JNK in serine phosphorylation, translocation, and degradation of IRS-1
K Hiratani et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
The pathobiology of diabetic complications - A unifying mechanism
M Brownlee
DIABETES (2005)
Reversal of nonalcoholic hepatic steatosis, hepatic insulin resistance, and hyperglycemia by moderate weight reduction in patients with type 2 diabetes
KF Petersen et al.
DIABETES (2005)
The endoplasmic reticulum chaperone improves insulin resistance in type 2 diabetes
K Ozawa et al.
DIABETES (2005)
Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
DS Cai et al.
NATURE MEDICINE (2005)
IKK-β links inflammation to obesity-induced insulin resistance
MC Arkan et al.
NATURE MEDICINE (2005)
Decreased insulin-stimulated ATP synthesis and phosphate transport in muscle of insulin-resistant offspring of type 2 diabetic parents
KF Petersen et al.
PLOS MEDICINE (2005)
Sulfonylurea induced beta-cell apoptosis in cultured human islets
K Maedler et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)
Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes
VB Ritov et al.
DIABETES (2005)
Predictors of and longitudinal changes in insulin sensitivity and secretion preceding onset of type 2 diabetes
V Lyssenko et al.
DIABETES (2005)
Tumor necrosis factor α produces insulin resistance in skeletal muscle by activation of inhibitor κB kinase in a p38 MAPK-dependent manner
C de Alvaro et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Structural and functional abnormalities in the islets isolated from type 2 diabetic subjects
SP Deng et al.
DIABETES (2004)
Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
KF Petersen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Role of the adipocyte, free fatty acids, and ectopic fat in pathogenesis of type 2 diabetes mellitus: Peroxisomal proliferator-activated receptor agonists provide a rational therapeutic approach
H Bays et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)
Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies
OJ Shah et al.
CURRENT BIOLOGY (2004)
Drug therapy: Thiazolidinediones
H Yki-Jarvinen
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease
VT Samuel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Rosiglitazone improves downstream insulin receptor signaling in type 2 diabetic patients
Y Miyazaki et al.
DIABETES (2003)
Mitochondrial dysfunction in the elderly: Possible role in insulin resistance
KF Petersen et al.
SCIENCE (2003)
Association of hypoglycemia and cardiac ischemia - A study based on continuous monitoring
C Desouza et al.
DIABETES CARE (2003)
The diabetes risk score -: A practical tool to predict type 2 diabetes risk
J Lindström et al.
DIABETES CARE (2003)
The influence of GLP-1 on glucose-stimulated insulin secretion -: Effects on β-cell sensitivity in type 2 and nondiabetic subjects
LL Kjems et al.
DIABETES (2003)
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle
CL Yu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
A multivariate logistic regression equation to screen for diabetes - Development and validation
BP Tabaei et al.
DIABETES CARE (2002)
Glucagon dose-response curve for hepatic glucose production and glucose disposal in type 2 diabetic patients and normal individuals
M Matsuda et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2002)
Defective amplification of the late phase insulin response to glucose by GIP in obese Type II diabetic patients
T Vilsboll et al.
DIABETOLOGIA (2002)
Acarbose for prevention of type 2 diabetes mellitus: the STOPNIDDM randomised trial
JL Chiasson et al.
LANCET (2002)
Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy
KF Petersen et al.
JOURNAL OF CLINICAL INVESTIGATION (2002)
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
WC Knowler et al.
NEW ENGLAND JOURNAL OF MEDICINE (2002)
Diet, lifestyle, and the risk of type 2 diabetes mellitus in women.
FB Hu et al.
NEW ENGLAND JOURNAL OF MEDICINE (2001)
Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of IKKβ
MS Yuan et al.
SCIENCE (2001)
Prevention of fat-induced insulin resistance by salicylate
JK Kim et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance.
J Tuomilehto et al.
NEW ENGLAND JOURNAL OF MEDICINE (2001)
Cardiovascular morbidity and mortality associated with the metabolic syndrome
B Isomaa et al.
DIABETES CARE (2001)
Renal gluconeogenesis - Its importance in human glucose homeostasis
JE Gerich et al.
DIABETES CARE (2001)
Pioglitazone hydrochloride monotherapy improves glycemic control in the treatment of patients with type 2 diabetes - A 6-month randomized placebo-controlled dose-response study
S Aronoff et al.
DIABETES CARE (2000)
Screening for type 2 diabetes
MM Engelgau et al.
DIABETES CARE (2000)
Association of systolic blood pressure with macrovascular and microvascular complications of type 2 diabetes (UKPDS 36): prospective observational study
AI Adler et al.
BMJ-BRITISH MEDICAL JOURNAL (2000)
Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study
IM Stratton et al.
BMJ-BRITISH MEDICAL JOURNAL (2000)
Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients
A Krook et al.
DIABETES (2000)
Insulin resistance differentially affects the PI3-kinase- and MAP kinase-mediated signaling in human muscle
K Cusi et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
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