4.7 Review

Recent advances in directed C-H functionalizations using monodentate nitrogen-based directing groups

Journal

ORGANIC CHEMISTRY FRONTIERS
Volume 1, Issue 7, Pages 843-895

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4qo00068d

Keywords

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Funding

  1. 973 Program [2011CB932404, 2011CBA00501]
  2. NSFC [21301173, 21332001, 21302184, 21202164]

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The use of directing groups has proven to be a successful strategy to enhance reactivity and control selectivity in C-H functionalization reactions. In the past decade, a multitude of new transformations and new directing groups have been explored, and several recent reviews have discussed directing group approaches for C-H functionalization. This review focuses specifically on the use of monodentate nitrogen-based directing groups published during the past two years, with the aim of covering a body of literature that is complementary to existing reviews.

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