Journal
ORGANIC CHEMISTRY FRONTIERS
Volume 1, Issue 11, Pages 1280-1284Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4qo00240g
Keywords
-
Categories
Funding
- National Basic Research Program of China [2015CB931900]
- Syngenta PhD Fellowship
- National Natural Science Foundation [21032006, 21172240, 21421002, 21472222]
- Science and Technology Commission of Shanghai Municipality [14ZR1448800]
- Chinese Academy of Sciences
Ask authors/readers for more resources
Copper-catalyzed tandem trifluoromethylation/cyclization of internal alkynes with Umemoto's reagent leads to 3-trifluoromethyl-1,2-dihydronaphthalene derivatives in moderate to good yields. The utility of this copper-catalyzed tandem reaction was demonstrated by oxidizing and reducing the trifluoromethylated product to give naphthalene and tetrahydronaphthalene, respectively, and the development of a short route to a trifluoromethylated analogue of Nafoxidine.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available