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Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans
Caroline J. Breitbach et al.
NATURE (2011)
Immune parameters affecting the efficacy of chemotherapeutic regimens
Laurence Zitvogel et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2011)
Mitotic catastrophe: a mechanism for avoiding genomic instability
Ilio Vitale et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)
NORMALIZATION OF THE VASCULATURE FOR TREATMENT OF CANCER AND OTHER DISEASES
Shom Goel et al.
PHYSIOLOGICAL REVIEWS (2011)
Sodium Iodide Symporter (NIS)-Mediated Radiovirotherapy for Pancreatic Cancer
Alan R. Penheiter et al.
AMERICAN JOURNAL OF ROENTGENOLOGY (2010)
Identification of the ENT1 Antagonists Dipyridamole and Dilazep as Amplifiers of Oncolytic Herpes Simplex Virus-1 Replication
Brent J. Passer et al.
CANCER RESEARCH (2010)
Myxoma Virus Virotherapy for Glioma in Immunocompetent Animal Models: Optimizing Administration Routes and Synergy with Rapamycin
XueQing Lun et al.
CANCER RESEARCH (2010)
miR-181a and miR-630 Regulate Cisplatin-Induced Cancer Cell Death
Lorenzo Galluzzi et al.
CANCER RESEARCH (2010)
Preparing an oncolytic poliovirus recombinant for clinical application against glioblastoma multiforme
Christian Goetz et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2010)
Novel oncolytic viruses: Riding high on the next wave?
Marianne M. Stanford et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2010)
Phase I/II Study of Oncolytic Herpes Simplex Virus NV1020 in Patients with Extensively Pretreated Refractory Colorectal Cancer Metastatic to the Liver
Sunil K. Geevarghese et al.
HUMAN GENE THERAPY (2010)
Attenuation of Vesicular Stomatitis Virus Encephalitis through MicroRNA Targeting
Elizabeth J. Kelly et al.
JOURNAL OF VIROLOGY (2010)
Transcriptional and Translational Dual-regulated Oncolytic Herpes Simplex Virus Type 1 for Targeting Prostate Tumors
Cleo Y. F. Lee et al.
MOLECULAR THERAPY (2010)
Potentiating Cancer Immunotherapy Using an Oncolytic Virus
Byram W. Bridle et al.
MOLECULAR THERAPY (2010)
Systemic Therapy of Disseminated Myeloma in Passively Immunized Mice Using Measles Virus-infected Cell Carriers
Chunsheng Liu et al.
MOLECULAR THERAPY (2010)
Hyaluronidase Expression by an Oncolytic Adenovirus Enhances Its Intratumoral Spread and Suppresses Tumor Growth
Sonia Guedan et al.
MOLECULAR THERAPY (2010)
Arsenic trioxide inhibits DNA methyltransferase and restores expression of methylation-silenced CDKN2B/CDKN2A genes in human hematologic malignant cells
Hai-Ying Fu et al.
ONCOLOGY REPORTS (2010)
Gene Therapy: The First Approved Gene-Based Medicines, Molecular Mechanisms and Clinical Indications
J. Raty et al.
Current Molecular Pharmacology (2010)
Systemic targeting of metastatic human breast tumor xenografts by Coxsackievirus A21
Kathryn A. Skelding et al.
BREAST CANCER RESEARCH AND TREATMENT (2009)
Antitumor Activity of an Oncolytic Adenoviral-CD40 Ligand (CD154) Transgene Construct in Human Breast Cancer Cells
Erica M. Gomes et al.
CLINICAL CANCER RESEARCH (2009)
Reovirus-based therapy for cancer
Kevin Kelly et al.
EXPERT OPINION ON BIOLOGICAL THERAPY (2009)
Genetically engineered Newcastle disease virus for malignant melanoma therapy
D. Zamarin et al.
GENE THERAPY (2009)
Chemical Modification with High Molecular Weight Polyethylene Glycol Reduces Transduction of Hepatocytes and Increases Efficacy of Intravenously Delivered Oncolytic Adenovirus
Konstantin Doronin et al.
HUMAN GENE THERAPY (2009)
Oncolytic adenovirus mediated Survivin knockdown by RNA interference suppresses human colorectal carcinoma growth in vitro and in vivo
Wei Shen et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2009)
Evaluation of IRES-mediated, cell-type-specific cytotoxicity of poliovirus using a colorimetric cell proliferation assay
Xiaoyi Yang et al.
JOURNAL OF VIROLOGICAL METHODS (2009)
Myxoma Virus Expressing Interleukin-15 Fails To Cause Lethal Myxomatosis in European Rabbits
Jia Liu et al.
JOURNAL OF VIROLOGY (2009)
Vesicular Stomatitis Virus as a Novel Cancer Vaccine Vector to Prime Antitumor Immunity Amenable to Rapid Boosting With Adenovirus
Byram W. Bridle et al.
MOLECULAR THERAPY (2009)
Phase Ib Trial of Mutant Herpes Simplex Virus G207 Inoculated Pre- and Post-tumor Resection for Recurrent GBM
James M. Markert et al.
MOLECULAR THERAPY (2009)
Conditional and reversible disruption of essential herpesvirus proteins
Mandy Glass et al.
NATURE METHODS (2009)
Targeted delivery of a suicide gene to human colorectal tumors by a conditionally replicating vaccinia virus
J. Foloppe et al.
GENE THERAPY (2008)
Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: a phase I trial
Byeong-Ho Park et al.
LANCET ONCOLOGY (2008)
Delta-24-RGD in combination with RAD001 induces enhanced anti-glioma effect via autophagic cell death
Marta M. Alonso et al.
MOLECULAR THERAPY (2008)
A let-7 microRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication
Robert E. Edge et al.
MOLECULAR THERAPY (2008)
Chemical control of protein stability and function in living mice
Laura A. Banaszynski et al.
NATURE MEDICINE (2008)
Engineering microRNA responsiveness to decrease virus pathogenicity
Elizabeth J. Kelly et al.
NATURE MEDICINE (2008)
Reprogrammed viruses as cancer therapeutics: targeted, armed and shielded
Roberto Cattaneo et al.
NATURE REVIEWS MICROBIOLOGY (2008)
Directed Evolution Generates a Novel Oncolytic Virus for the Treatment of Colon Cancer
Irene Kuhn et al.
PLOS ONE (2008)
Viral control of mitochondrial apoptosis
Lorenzo Galluzzi et al.
PLOS PATHOGENS (2008)
Erlotinib exhibits antineoplastic off-target effects in AML and MDS:: a preclinical study
Simone Boehrer et al.
BLOOD (2008)
Seneca valley virus, a systemically deliverable oncolytic picornavirus, and the treatment of neuroendocrine cancers
P. Seshidhar Reddy et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2007)
Examination of the therapeutic potential of Delta-24-RGD in brain tumor stem cells: Role of autophagic, cell death
Hong Jiang et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2007)
Oncolytic viruses in cancer therapy
Markus J. V. Vaha-Koskela et al.
CANCER LETTERS (2007)
Systemic toxicity-efficacy profile of ICOVIR-5, a potent and selective oncolytic adenovirus based on the pRB pathway
Manel Cascallo et al.
MOLECULAR THERAPY (2007)
ICOVIR-5 shows E2F1 addiction and potent antiglioma effect in vivo
Marta M. Alonso et al.
CANCER RESEARCH (2007)
Combination of the oncolytic adenovirus ICOVIR-5 with chemotherapy provides enhanced anti-glioma effect in vivo
M. M. Alonso et al.
CANCER GENE THERAPY (2007)
The antitumor activity of TRAIL and IL-24 with replicating oncolytic adenovirus in colorectal cancer
L. Zhao et al.
CANCER GENE THERAPY (2006)
The oncolytic effect in vivo of reovirus on tumour cells that have survived reovirus cell killing in vitro
T. Alain et al.
BRITISH JOURNAL OF CANCER (2006)
Oncolytic adenoviral vector carrying the cytosine deaminase gene for melanoma gene therapy
Y. Liu et al.
CANCER GENE THERAPY (2006)
Oncolytic capacity of attenuated replicative Semliki Forest virus in human melanoma xenografts in severe combined immunodeficient mice
Markus J. V. Vaha-Koskela et al.
CANCER RESEARCH (2006)
Oncolysis of pancreatic tumour cells by a γ34.5-deleted HSV-1 does not rely upon Ras-activation, but on the Pl 3-kinase pathway
F. Sarinella et al.
GENE THERAPY (2006)
Enhanced baculovirus-mediated transduction of human cancer cells by tumor-homing peptides
Anna R. Makela et al.
JOURNAL OF VIROLOGY (2006)
Concurrent delivery of GM-CSF and B7-1 using an oncolytic adenovirus elicits potent antitumor effect
K-J Choi et al.
GENE THERAPY (2006)
Differentially regulated interferon response determines the outcome of Newcastle disease virus infection in normal and tumor cell lines
Sateesh Krishnamurthy et al.
JOURNAL OF VIROLOGY (2006)
Lentivirus-mediated gene therapy by suppressing survivin in BALB/c nude mice bearing oral squamous cell carcinoma
Gaofeng Jiang et al.
CANCER BIOLOGY & THERAPY (2006)
Overcoming physiologic barriers to cancer treatment by molecularly targeting the tumor microenvironment
R Cairns et al.
MOLECULAR CANCER RESEARCH (2006)
CG0070, a conditionally replicating granulocyte macrophage colony-stimulating factor-armed oncolytic adenovirus for the treatment of bladder cancer
N Ramesh et al.
CLINICAL CANCER RESEARCH (2006)
Combined HSV-TK/IL-2 gene therapy in patients with recurrent glioblastoma multiforme:: biological and clinical results
F Colombo et al.
CANCER GENE THERAPY (2005)
Influenza immunisation in children with solid tumours
J Chisholm et al.
EUROPEAN JOURNAL OF CANCER (2005)
Combination of gemcitabine and Ad5/3-D24, a tropism modified conditionally replicating adenovirus, for the treatment of ovarian cancer
M Raki et al.
GENE THERAPY (2005)
Epidemiology and outcomes of serious influenza-related infections in the cancer population
CD Cooksley et al.
CANCER (2005)
Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
RK Jain
SCIENCE (2005)
Treatment of rapidly growing K-BALB and CT26 mouse tumours using Semliki Forest virus and its derived vector
JWP Smyth et al.
GENE THERAPY (2005)
Noninvasive dual modality in vivo monitoring of the persistence and potency of a tumor targeted conditionally replicating adenovirus
A Kanerva et al.
GENE THERAPY (2005)
Xenograft models for liver metastasis: Relationship between tumor morphology and adenovirus vector transduction
ZY Li et al.
MOLECULAR THERAPY (2004)
Angiogenesis inhibition by an oncolytic herpes virus expressing interleukin 12
RJ Wong et al.
CLINICAL CANCER RESEARCH (2004)
Systemic therapy of malignant human melanoma tumors by a common cold-producing enterovirus, coxsackievirus A21
DR Shafren et al.
CLINICAL CANCER RESEARCH (2004)
The effect of sequestration by nontarget tissues on anti-tumor efficacy of systemically applied, conditionally replicating adenovirus vectors
KM Bernt et al.
MOLECULAR THERAPY (2003)
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
S Hacein-Bey-Abina et al.
SCIENCE (2003)
VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents
DF Stojdl et al.
CANCER CELL (2003)
Enhanced therapeutic efficacy for ovarian cancer with a serotype 3 receptor-targeted oncolytic adenovirus
A Kanerva et al.
MOLECULAR THERAPY (2003)
Acquired resistance to cytolysis of the E1B-attenuated adenovirus, dl1520, in ovarian tumour cell lines
YT Kim et al.
CANCER GENE THERAPY (2003)
Common community respiratory viruses in patients with cancer - More than just common colds
KL Hicks et al.
CANCER (2003)
Preclinical characterization of the antiglioma activity of a tropism-enhanced adenovirus targeted to the retinoblastoma pathway
J Fueyo et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2003)
A novel hypoxia-inducible factor (HIF) activated oncolytic adenovirus for cancer therapy
DE Post et al.
ONCOGENE (2003)
ICP34.5 deleted herpes simplex virus with enhanced oncolytic, immune stimulating, and anti-tumour properties
BL Liu et al.
GENE THERAPY (2003)
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency
S Hacein-Bey-Abina et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Age-dependent effects of repeated immunization with a first generation adenovirus vector on the immune response and transgene expression in young and old rats
I Massari et al.
EXPERIMENTAL GERONTOLOGY (2002)
Inhibition of murine prostate tumor growth and activation of immunoregulatory cells with recombinant canarypox viruses
TS Griffith et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2001)
Live attenuated measles virus induces regression of human lymphoma xenografts in immunodeficient mice
D Grote et al.
BLOOD (2001)
Oncolytic herpes simplex virus vector with enhanced MHC class I presentation and tumor cell killing
T Todo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies
KD Fisher et al.
GENE THERAPY (2001)
Intralesional injection of herpes simplex virus 1716 in metastatic melanoma
RM MacKie et al.
LANCET (2001)
A blood-tumor barrier limits gene transfer to experimental liver cancer: the effect of vasoactive compounds
R Bilbao et al.
GENE THERAPY (2000)
Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus
DF Stojdl et al.
NATURE MEDICINE (2000)
Adenovirus-mediated transfer of p53 and Fas ligand drastically enhances apoptosis in gliomas
N Shinoura et al.
CANCER GENE THERAPY (2000)
Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial
JM Markert et al.
GENE THERAPY (2000)
Complement depletion facilitates the infection of multiple brain tumors by an intravascular, replication-conditional herpes simplex virus mutant
K Ikeda et al.
JOURNAL OF VIROLOGY (2000)
Engineered herpes simplex virus expressing IL-12 in the treatment of experimental murine brain tumors
JN Parker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)