Journal
ONCOIMMUNOLOGY
Volume 3, Issue 6, Pages -Publisher
LANDES BIOSCIENCE
DOI: 10.4161/onci.29181
Keywords
anticancer peptides; B16 melanoma; intralesional treatment; inflammation; immunogenic cell death; DAMPs
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Several cationic antimicrobial peptides demonstrate promising anticancer effects. We have recently described the anticancer properties of LTX-315, a novel synthetic anticancer peptide, against syngeneic B16 melanomas. LTX-315 induced a complete regression of B16 melanomas and systemic protective immune responses following intralesional administration of the peptide.
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