Journal
ONCOIMMUNOLOGY
Volume 2, Issue 4, Pages -Publisher
LANDES BIOSCIENCE
DOI: 10.4161/onci.23565
Keywords
angiogenesis; galectins; gene signature; metastasis; prostate cancer
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Galectins, a family of glycan-binding proteins, can control tumor progression by promoting transformation, angiogenesis and immune escape. We identified a dynamically regulated galectin signature', which delineates the progression of prostate cancer, highlighting galectin-1 as an attractive target for anti-angiogenic therapy in advanced stages of the disease.
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