Journal
ONCOIMMUNOLOGY
Volume 2, Issue 12, Pages -Publisher
LANDES BIOSCIENCE
DOI: 10.4161/onci.27138
Keywords
chemotherapy; danger-associated molecular patterns; immunogenic cell death; mitoxantrone; oncolytic virus
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Oncolytic viruses are novel immunotherapeutic agents that appear to mediate potent antineoplastic effects in both preclinical and clinical settings. Recent studies demonstrate that manipulating the mechanisms whereby cancer cells die in the course of oncolytic virotherapy has potential to boost anticancer immune responses.
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