Journal
ONCOIMMUNOLOGY
Volume 2, Issue 11, Pages -Publisher
LANDES BIOSCIENCE
DOI: 10.4161/onci.26470
Keywords
blood vessels; breast cancer; dendritic cells; HEV; lymphocytes
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Accumulating evidence suggests that high-endothelial venules (HEVs) represent major gateways for the infiltration of lymphocytes within neoplastic lesions. However, the origin of these vessels in human neoplasms remains elusive. We have recently discovered a link between lymphotoxin beta-producing dendritic cells and tumor-associated HEVs.
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