Journal
ONCOIMMUNOLOGY
Volume 1, Issue 5, Pages 751-753Publisher
TAYLOR & FRANCIS INC
DOI: 10.4161/onci.19570
Keywords
dendritic cells; tumour microenvironment; VEGF; CCL2; CXCL1; CXCL5
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Tumors inhibit dendritic cell maturation and function in order to evade host immunity. We showed that conditioned media from tumor explant tissue, taken from metastatic colorectal cancer patients, significantly inhibits maturation of dendritic cells.
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