4.6 Editorial Material Retracted Publication

被撤回的出版物: FOXO3 A master switch for regulating tolerance and immunity in dendritic cells (Retracted article. See vol. 5, 2016)

Journal

ONCOIMMUNOLOGY
Volume 1, Issue 2, Pages 252-254

Publisher

TAYLOR & FRANCIS INC
DOI: 10.4161/onci.1.2.18241

Keywords

tumor; dendritic cells; tolerance; Foxo3; immunotherapy

Funding

  1. NIH, NCI

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Recent findings demonstrate that dendritic cells in prostate tumors induce immune tolerance in tumor antigen-specific CD8(+) T cells. We propose that DC tolerogenicity can be regulated by expression of Foxo3; silencing Foxo3 expression enhances anti-tumor immune responses and renders FOXO3 a potential target for immunotherapy.

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