Journal
ONCOIMMUNOLOGY
Volume 1, Issue 4, Pages -Publisher
TAYLOR & FRANCIS INC
DOI: 10.4161/onci.19531
Keywords
cancer genetics; immunotherapy; immune responsiveness; cancer microenvironment; melanoma
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A cancer immune signature implicating good prognosis and responsiveness to immunotherapy was described that is observed also in other aspects of immune-mediated, tissue-specific destruction (TSD). Its determinism remains, however, elusive. Based on limited but unique clinical observations, we propose a multifactorial genetic model of human cancer immune responsiveness.
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