Journal
ONCOIMMUNOLOGY
Volume 1, Issue 7, Pages 1169-1171Publisher
TAYLOR & FRANCIS INC
DOI: 10.4161/onci.20955
Keywords
mathematical model; in-treatment; personalization; prostate cancer; clinical trial
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Despite great expectations and research efforts, anticancer immunotherapy has not yet become a definitive cure. Perhaps, this is because past reductionist approaches were too simplistic for the patient-specific complex system of co-evolving tumor cells and host immunity. Recent efforts based on a systems-based approach promise improved clinical outcomes engendered by a dynamic modification of personalized therapeutic regimens.
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