Journal
ONCOIMMUNOLOGY
Volume 1, Issue 6, Pages 992-994Publisher
LANDES BIOSCIENCE
DOI: 10.4161/onci.20239
Keywords
T lymphocyte; human lung tumor; stroma; chemokines; extracellular matrix; migration
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In principle, T cells can recognize and kill cancer cells. However, tumors have the ability to escape T cell attack. By imaging the dynamic behavior of T cells in human lung tumor explants, we have recently established the importance of the extracellular matrix in limiting access of T cells to tumor cells.
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