Journal
ONCOIMMUNOLOGY
Volume 1, Issue 7, Pages 1208-1210Publisher
LANDES BIOSCIENCE
DOI: 10.4161/onci.20779
Keywords
bystander CD8 T cells; NKG2D; antigen non-specific T cells; LAK cells; cytokine induced killer cells; cancer immunotherapy
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For a long time, cancer immunotherapy has focused on the induction of tumor-specific T cell-mediated immune responses. Now, a mounting body of evidence indicates that efficient anticancer immune responses also rely on innate immunity. Tietze et al. have recently elucidated an antigen-nonspecific role for memory CD8(+) T cells in cytokine-based cancer immunotherapy.
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