Journal
ONCOIMMUNOLOGY
Volume 1, Issue 4, Pages -Publisher
TAYLOR & FRANCIS INC
DOI: 10.4161/onci.19367
Keywords
NK cells; platelets; thrombocytes; cancer; metastasis; MHC Class I; tumor immunosurveillance
Categories
Ask authors/readers for more resources
Metastasis is strongly inhibited in thrombocytopenic mice. This phenotype is reversed by NK cell depletion which indicates that platelets may facilitate tumor progression and metastasis by interfering with NK cell immunosurveillance. Understanding the underlying mechanisms may help us to reinforce anti-tumor immunity and NK-based immunotherapy in cancer patients.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
