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Cytomegalovirus Pneumonia in Hematopoietic Stem Cell Recipients

Journal

JOURNAL OF INTENSIVE CARE MEDICINE
Volume 29, Issue 4, Pages 200-212

Publisher

SAGE PUBLICATIONS INC
DOI: 10.1177/0885066613476454

Keywords

cytomegalovirus; CMV pneumonia; hematopoietic cell transplant; antiviral; prevention

Funding

  1. NIH [K23HL096831]
  2. ASBMT/Viropharma New Investigator Award

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Cytomegalovirus (CMV) is a frequently encountered infection following hematopoietic cell transplantation, and tissue invasive pneumonia is a dreaded complication of the virus in this population. In this review of CMV pneumonia, we address epidemiology, pathogenesis, diagnostics, current therapy, and strategies to prevent the development of CMV. We also review emerging treatment and prevention options for this challenging disease.

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