Journal
JOURNAL OF CELL COMMUNICATION AND SIGNALING
Volume 4, Issue 3, Pages 119-130Publisher
SPRINGER
DOI: 10.1007/s12079-010-0098-7
Keywords
CCN proteins; Matricellular; Nuclear localization; Review
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CCN5 is one of six proteins in the CCN family. This family of proteins has been shown to play important roles in many processes, including proliferation, migration, adhesion, extracellular matrix regulation, angiogenesis, tumorigenesis, fibrosis, and implantation. In this review, we focus on the biological and putative pathophysiological roles of CCN5. This intriguing protein is structurally unique among the CCN family members, and has a unique biological activity profile as well.
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