Journal
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
Volume 2, Issue 3, Pages 243-250Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jaip.2014.02.012
Keywords
Anaphylaxis; Idiopathic anaphylaxis; Mast cell activating syndrome; Mast cell activating disorder; Galactose-alpha-1,3-galactose
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Funding
- Mylan
- Sanofi
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Idiopathic anaphylaxis is a perplexing problem that accounts for approximately 30% to 60% of cases of anaphylaxis in ambulatory adults and perhaps 10% of cases in children. Advances in our knowledge of idiopathic anaphylaxis have occurred over the past decade with the elucidation of mast cell activating disorders and the discovery of episodes of anaphylaxis caused by galactose-alpha-1,3-galactose. Most patients do well because fatalities can usually be prevented with proper therapy, and many individuals, for reasons not understood, undergo spontaneous remission. (C) 2014 American Academy of Allergy, Asthma & Immunology
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