Journal
FRONTIERS IN NEUROLOGY
Volume 5, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fneur.2014.00179
Keywords
tinnitus; hyperacusis; lick suppression; operant conditioning; startle reflex; reaction time; behavior
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Funding
- NIH National Institute on Deafness and Other Communication Disorders [R01DC011808, R01DC009219]
- Office of Naval Research [N000141210731]
- National Defense Science and Engineering Graduate Research Fellowship
- NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS [R01DC011808] Funding Source: NIH RePORTER
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The phantom perception of tinnitus and reduced sound-level tolerance associated with hyperacusis have a high comorbidity and can be debilitating conditions for which there are no widely accepted treatments. One factor limiting the development of treatments for tinnitus and hyperacusis is the lack of reliable animal behavioral models of these disorders. Therefore, the purpose of this review is to highlight the current animal models of tinnitus and hyperacusis, and to detail the advantages and disadvantages of each paradigm. To date, this is the first review to include models of both tinnitus and hyperacusis.
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