Journal
FRONTIERS OF MEDICINE
Volume 12, Issue 4, Pages 463-472Publisher
SPRINGER
DOI: 10.1007/s11684-018-0668-2
Keywords
T cell immunity; metabolic pathways; nutrient uptake; metabolic checkpoints
Categories
Funding
- National Natural Science Foundation of China [81430033, 31470845, 31670896]
- Recruitment Program of Global Experts of China
- Shanghai Rising-Star Program [16QA1403300]
- Shanghai Science and Technology Committee [16410723300]
- Shanghai Municipal Commission of Health and Family Planning [20174Y0049, 20174Y0191, 15GWZK0102]
- Shanghai Jiao Tong University Program for young teachers [KJ30214170006]
- Medical and Engineering Cross Research Foundation [YG2016QN77]
Ask authors/readers for more resources
T cells are an important adaptive immune response arm that mediates cell-mediated immunity. T cell metabolism plays a central role in T cell activation, proliferation, differentiation, and effector function. Specific metabolic programs are tightly controlled to mediate T cell immune responses, and alterations in T cell metabolism may result in many immunological disorders. In this review, we will summarize the main T cell metabolic pathways and the important factors participating in T cell metabolic programming during T cell homeostasis, differentiation, and function.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available