Journal
FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING
Volume 8, Issue 3, Pages 253-264Publisher
SPRINGER
DOI: 10.1007/s11705-014-1425-y
Keywords
theranostics; iron oxide nanoparticles; MRI; drug delivery; photothermal therapy; photodynamic therapy
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Theranostic platform, which is equipped with both diagnostic and therapeutic functions, is a promising approach in cancer treatment. From various nanotheranostics studied, iron oxide nanoparticles have advantages since IONPs have good biocompatibility and spatial imaging capability. This review is focused on the IONP-based nanotheranostics for cancer imaging and treatment. The most recent progress for applications of IONP nanotheranostics is summarized, which includes IONP-based diagnosis, magnetic resonance imaging (MRI), multimodal imaging, chemotherapy, hyperthermal therapy, photodynamic therapy, and gene delivery. Future perspectives and challenges are also outlined for the potential development of IONP based theranostics in clinical use.
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