The correlation between mental health and multiple chemical sensitivity: a survey study in Japanese workers

This study was designed to determine the correlation between mental health and multiple chemical sensitivity (MCS). The present study was conducted at two companies in 2011; both in Kyushu, Japan. The subjective symptoms subscale of the Self-diagnosis Checklist for Assessment of Workers' Accumulated Fatigue was used as a mental health subscale. To determine if multiple chemical exposure has an impact on mental health, we composed an original path model using structural equation analysis. Our final path model can be regarded as good: CMIN/DF = 1.832, CFI = 0.996, and RMSEA = 0.038, AIC = 71.158. As expected, chemical sensitivity and other chemical sensitivity scores predicted the health effects of multiple chemical exposure (beta = 0.19, 0.64). Mental health was predicted by symptom severity and life impact (beta = 0.56 and 0.12), which were both affected by multiple chemical exposure (beta = 0.38 and 0.89, respectively). As far as we are aware, this is the first study using path analysis to explore whether MCS can indicate mental health in worker populations worldwide, and we found a significant causal relationship between them. This could indicate that more focus should be placed on the impact of MCS on mental health in future investigations.