Journal
ORGANIC CHEMISTRY FRONTIERS
Volume 2, Issue 6, Pages 739-752Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5qo00016e
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- University of Maryland School of Pharmacy
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The Mitsunobu reaction was first described almost fifty years ago and has enjoyed immense popularity since its inception. The purpose of this review is to focus on the more recent advances and applications of Mitsunobu chemistry, particularly from the 1990s to the present day. In addition to a discussion of newer reagents that facilitate purification, we will describe more contemporary applications of this chemistry, especially as applied to the synthesis of pharmaceuticals and their precursors.
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