Journal
THERAPEUTIC ADVANCES IN GASTROENTEROLOGY
Volume 7, Issue 1, Pages 38-50Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/1756283X13501786
Keywords
visceral adiposity; inflammation; adipose tissue; carcinogenesis; signalling pathways
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Funding
- Irish Cancer Society research scholarship
- Irish Research Council for Science, Engineering and Technology scholarship
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There is increasing recognition of the impact of being overweight and obese on the development of cancers at diverse sites including the gastrointestinal tract. Large epidemiological studies indicate that up to 14% of tumours may be related to obesity. Pathophysiological mechanisms underpinning this association are not well understood and so are discussed in this review.
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