4.6 Article

Interactions of graphene and graphene oxide with proteins and peptides

Journal

NANOTECHNOLOGY REVIEWS
Volume 2, Issue 1, Pages 27-45

Publisher

WALTER DE GRUYTER GMBH
DOI: 10.1515/ntrev-2012-0078

Keywords

enzyme; graphene; graphene oxide; interaction; peptide; protein

Funding

  1. National Science foundation of China [91123011, 90923041, 31070742]
  2. State Key Laboratory of Bioreactor Engineering [2060204]
  3. 111 Project [B07023]
  4. Science and Technology Commission of Shanghai Municipality [11DZ2260600]
  5. National 973 Program of China [2010CB933900]

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This review selectively describes the recent progress in the interactions of proteins (enzymes) and short-chain peptides with graphene and graphene oxide (GO). Particularly, the advances of the immobilization mechanisms of enzymes on graphene and GO, the catalytic properties of the immobilized enzymes, and their applications are summarized in detail. The interfacings of the peptides with graphene and GO, the as assembled conjugates, and their potential applications are discussed briefly. The possible ongoing development for the assembly of conjugates of graphene and GO with proteins and peptides in a controlled manner is speculated upon.

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