Related references
Note: Only part of the references are listed.SPARC independent drug delivery and antitumour effects of nab-paclitaxel in genetically engineered mice
Albrecht Neesse et al.
GUT (2014)
Stromal disrupting effects of nab-paclitaxel in pancreatic cancer
R. Alvarez et al.
BRITISH JOURNAL OF CANCER (2013)
Recent progress in pancreatic cancer
Christopher L. Wolfgang et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2013)
Hypoxia Triggers Hedgehog-Mediated Tumor-Stromal Interactions in Pancreatic Cancer
Taly R. Spivak-Kroizman et al.
CANCER RESEARCH (2013)
Pirfenidone Inhibits Pancreatic Cancer Desmoplasia by Regulating Stellate Cells
Shingo Kozono et al.
CANCER RESEARCH (2013)
Current concepts and novel targets in advanced pancreatic cancer
Patrick Michl et al.
GUT (2013)
Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
Michael A. Jacobetz et al.
GUT (2013)
A multicenter phase II trial of gemcitabine and candesartan combination therapy in patients with advanced pancreatic cancer: GECA2
Yousuke Nakai et al.
INVESTIGATIONAL NEW DRUGS (2013)
Hypoxia enhances the interaction between pancreatic stellate cells and cancer cells via increased secretion of connective tissue growth factor
Daiki Eguchi et al.
JOURNAL OF SURGICAL RESEARCH (2013)
Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine
Daniel D. Von Hoff et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Tumor-stromal interactions in pancreatic cancer
Jo Tod et al.
PANCREATOLOGY (2013)
Emerging targets in pancreatic cancer: epithelial-mesenchymal transition and cancer stem cells
Jason A. Castellanos et al.
ONCOTARGETS AND THERAPY (2013)
Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels
Vikash P. Chauhan et al.
NATURE COMMUNICATIONS (2013)
Alteration of pancreatic cancer cell functions by tumor-stromal cell interaction
Shin Hamada et al.
FRONTIERS IN PHYSIOLOGY (2013)
The biological kinship of hypoxia with CSC and EMT and their relationship with deregulated expression of miRNAs and tumor aggressiveness
Bin Bao et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2012)
Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma
Paolo P. Provenzano et al.
CANCER CELL (2012)
Selective Tumor Hypoxia Targeting by Hypoxia-Activated Prodrug TH-302 Inhibits Tumor Growth in Preclinical Models of Cancer
Jessica D. Sun et al.
CLINICAL CANCER RESEARCH (2012)
The Pancreas Cancer Microenvironment
Christine Feig et al.
CLINICAL CANCER RESEARCH (2012)
StellaTUM: current consensus and discussion on pancreatic stellate cell research
Mert Erkan et al.
GUT (2012)
Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors
Triantafyllos Stylianopoulos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Why the stroma matters in breast cancer Insights into breast cancer patient outcomes through the examination of stromal biomarkers
Matthew W. Conklin et al.
CELL ADHESION & MIGRATION (2012)
The role of inflammatory cells in fostering pancreatic cancer cell growth and invasion
Anthony Evans et al.
FRONTIERS IN PHYSIOLOGY (2012)
Glucose Metabolism Gene Polymorphisms and Clinical Outcome in Pancreatic Cancer
Xiaoqun Dong et al.
CANCER (2011)
Hypoxia Predicts Aggressive Growth and Spontaneous Metastasis Formation from Orthotopically Grown Primary Xenografts of Human Pancreatic Cancer
Qing Chang et al.
CANCER RESEARCH (2011)
Stromal biology and therapy in pancreatic cancer
Albrecht Neesse et al.
GUT (2011)
Gemcitabine Plus nab-Paclitaxel Is an Active Regimen in Patients With Advanced Pancreatic Cancer: A Phase I/II Trial
Daniel D. Von Hoff et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Pancreatic cancer: understanding and overcoming chemoresistance
Zhiwei Wang et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2011)
Pancreatic Cancer: Pathobiology, Treatment Options, and Drug Delivery
Jing Li et al.
AAPS JOURNAL (2010)
Role of Pancreatic Stellate Cells in Pancreatic Cancer Metastasis
Zhihong Xu et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Pancreatic stellate cells promote epithelial-mesenchymal transition in pancreatic cancer cells
Kazuhiro Kikuta et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Inhibition of renin-angiotensin system affects prognosis of advanced pancreatic cancer receiving gemcitabine
Y. Nakai et al.
BRITISH JOURNAL OF CANCER (2010)
Contextual Synthetic Lethality and/or Loss of Heterozygosity: Tumor Hypoxia and Modification of DNA Repair
Norman Chan et al.
CLINICAL CANCER RESEARCH (2010)
Radiosensitization and Stromal Imaging Response Correlates for the HIF-1 Inhibitor PX-478 Given with or without Chemotherapy in Pancreatic Cancer
David L. Schwartz et al.
MOLECULAR CANCER THERAPEUTICS (2010)
Enzymatic Depletion of Tumor Hyaluronan Induces Antitumor Responses in Preclinical Animal Models
Curtis B. Thompson et al.
MOLECULAR CANCER THERAPEUTICS (2010)
Pancreatic Cancer
Manuel Hidalgo
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Isolation of Quiescent Human Pancreatic Stellate Cells: A Promising in vitro Tool for Studies of Human Pancreatic Stellate Cell Biology
Alain Vonlaufen et al.
PANCREATOLOGY (2010)
Pancreatic Stellate Cells Increase the Invasion of Human Pancreatic Cancer Cells through the Stromal Cell-Derived Factor-1/CXCR4 Axis
Zhenjun Gao et al.
PANCREATOLOGY (2010)
Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis
John M. L. Ebos et al.
CANCER CELL (2009)
Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis
Marta Paez-Ribes et al.
CANCER CELL (2009)
Cancer stem cell marker expression in hepatocellular carcinoma and liver metastases is not sufficient as single prognostic parameter
Alexei V. Salnikov et al.
CANCER LETTERS (2009)
Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer
Thiruvengadam Arumugam et al.
CANCER RESEARCH (2009)
Decreased Blood Flow with Increased Metabolic Activity: A Novel Sign of Pancreatic Tumor Aggressiveness
Gaber Komar et al.
CLINICAL CANCER RESEARCH (2009)
Epidemiology of pancreatic cancer: an overview
Sara Raimondi et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2009)
Pancreatic Islet and Stellate Cells Are the Main Sources of Endocrine Gland-Derived Vascular Endothelial Growth Factor/Prokineticin-1 in Pancreatic Cancer
Xiaohua Jiang et al.
PANCREATOLOGY (2009)
Oxygen Consumption Can Regulate the Growth of Tumors, a New Perspective on the Warburg Effect
Yijun Chen et al.
PLOS ONE (2009)
Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer
Kenneth P. Olive et al.
SCIENCE (2009)
Cancer-Stellate Cell Interactions Perpetuate the Hypoxia-Fibrosis Cycle in Pancreatic Ductal Adenocarcinoma
Mert M. Erkan et al.
NEOPLASIA (2009)
Hypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancer
Atsushi Masamune et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2008)
Pancreatic stellate cells and pancreatic cancer cells: An unholy alliance
Alain Vonlaufen et al.
CANCER RESEARCH (2008)
Pancreatic stellate cells: Partners in crime with pancreatic cancer cells
Alain Vonlaufen et al.
CANCER RESEARCH (2008)
Cancer-associated stroma fibroblasts promote pancreatic tumor progression
Rosa F. Hwang et al.
CANCER RESEARCH (2008)
The Activated Stroma Index Is a Novel and Independent Prognostic Marker in Pancreatic Ductal Adenocarcinoma
Mert Erkan et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2008)
Hypoxia, DNA repair and genetic instability
Robert G. Bristow et al.
NATURE REVIEWS CANCER (2008)
The hypoxic environment in tumor-stromal cells accelerates pancreatic cancer progression via the activation of paracrine hepatocyte growth factor/c-Met signaling
Takao Ide et al.
ANNALS OF SURGICAL ONCOLOGY (2007)
Pancreatic stellate cells are an important source of MMP-2 in human pancreatic cancer and accelerate tumor progression in a murine xenograft model and CAM assay
Wilhelm Schneiderhan et al.
JOURNAL OF CELL SCIENCE (2007)
The pancreatic stellate cell: a star on the rise in pancreatic diseases
M. Bishr Omary et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Hypoxia-inducible factor-1 (HIF-1)
Qingdong Ke et al.
MOLECULAR PHARMACOLOGY (2006)
Battle-scarred pancreas: Role of alcohol and pancreatic stellate cells in pancreatic fibrosis
Minoti V. Apte et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2006)
Existence of autocrine loop between interleukin-6 and transforming growth factor-β1 in activated rat pancreatic stellate cells
Hiroyoshi Aoki et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2006)
Autocrine loop between TGF-β1 and IL-1β through Smad3- and ERK-dependent pathways in rat pancreatic stellate cells
H Aoki et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
Targeting multidrug resistance in cancer
G Szakács et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Connective tissue growth factor (CCN2) in rat pancreatic stellate cell function:: Integrin ζ5β1 as a novel CCN2 receptor
RP Gao et al.
GASTROENTEROLOGY (2005)
Differential and synergistic effects of platelet-derived growth factor-BB and transforming growth factor-β1 on activated pancreatic stellate cells
C Kordes et al.
PANCREAS (2005)
Up-regulation of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor 1 (HIF-1)
AE Greijer et al.
JOURNAL OF PATHOLOGY (2005)
Loss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosis
M Erkan et al.
ONCOGENE (2005)
Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells
MG Bachem et al.
GASTROENTEROLOGY (2005)
Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and in terleukin-1β
S Müerköster et al.
CANCER RESEARCH (2004)
Desmoplastic reaction in pancreatic cancer - Role of pancreatic stellate cells
MV Apte et al.
PANCREAS (2004)
Tumor hypoxia correlates with metastatic tumor growth of pancreatic cancer in an orthotopic murine model
P Büchler et al.
JOURNAL OF SURGICAL RESEARCH (2004)
Tumor-stroma interaction of human pancreatic cancer: Acquired resistance to anticancer drugs and proliferation regulation is dependent on extracellular matrix proteins
H Miyamoto et al.
PANCREAS (2004)
Candesartan, an angiotensin II receptor antagonist, suppresses pancreatic inflammation and fibrosis in rats
T Yamada et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Activin A is an autocrine activator of rat pancreatic stellate cells: potential therapeutic role of follistatin for pancreatic fibrosis
N Ohnishi et al.
GUT (2003)
Prognostic significance of tumor oxygenation in humans
SM Evans et al.
CANCER LETTERS (2003)
Advanced pancreatic ductal cancer:: Fibrotic focus and β-catenin expression correlate with outcome
I Watanabe et al.
PANCREAS (2003)
Cell migration: a novel aspect of pancreatic stellate cell biology
PA Phillips et al.
GUT (2003)
Rat pancreatic stellate cells secrete matrix metal loproteinases: implications for extracellular matrix turnover
PA Phillips et al.
GUT (2003)
Pancreatic cancer biology and genetics
N Bardeesy et al.
NATURE REVIEWS CANCER (2002)
Expression of transforming growth factor-β1 by pancreatic stellate cells and its implications for matrix secretion and turnover in chronic pancreatitis
FWT Shek et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Pancreatic stellate cells respond to inflammatory cytokines: potential role in chronic pancreatitis
P Mews et al.
GUT (2002)
Independent function of two destruction domains in hypoxia-inducible factor-α chains activated by prolyl hydroxylation
N Masson et al.
EMBO JOURNAL (2001)
Pancreatic tumors show high levels of hypoxia
AC Koong et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2000)