4.3 Review

Magnetic responsive scaffolds and magnetic fields in bone repair and regeneration

Journal

FRONTIERS OF MATERIALS SCIENCE
Volume 8, Issue 1, Pages 20-31

Publisher

HIGHER EDUCATION PRESS
DOI: 10.1007/s11706-014-0232-1

Keywords

bone repair; magnetic scaffold; magnetic field; physical stimulation

Funding

  1. National Natural Science Foundation of China [30970710, 61127002]
  2. Beijing Municipal Natural Science Foundation [2102046]

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Increasing evidence shows that magnetic fields and magnetic responsive scaffolds can play unique roles in promoting bone repair and regeneration. This article addresses the synergistic effects of magnetic scaffolds in response to external magnetic fields on the bone regeneration in situ. Additionally, the exploration of using magnetic scaffolds as tools in the bone implant fixation, local drug delivery and mimicking microenvironment of stem cell differentiation are introduced. We also discussed possible underlying mechanisms and perspectives of magnetic responsive scaffolds in the bone repair and regeneration.

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